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Eukaryote cells have a flexible shape, which dynamically changes according to the function performed by the cell. One mechanism for deforming the cell membrane into the desired shape is through the expression of curved membrane proteins.…

生物物理 · 物理学 2018-12-05 Miha Fošnarič , Samo Penič , Aleš Iglič , Veronika Kralj-Iglič , Mitja Drab , Nir Gov

Soft and frangible materials that remodel under flow can give rise to branched patterns shaped by material properties, boundary conditions, and the time scales of forcing. We present a general theoretical framework for emergent branching in…

软凝聚态物质 · 物理学 2025-10-01 P. L. B. Fischer , J. Tauber , T. Koch , L. Mahadevan

Microswimmers and active colloids often move in confined systems, including those involving interfaces. Such interfaces, especially at the microscale, may deform in response to the stresses of the flow created by the active particle. We…

软凝聚态物质 · 物理学 2026-01-14 Adam Hitin Bialus , Bhargav Rallabandi , Naomi Oppenheimer

In quasi-two-dimensional experiments with photoelastic particles confined to an annular region, an intruder constrained to move in a circular path halfway between the annular walls experiences stick-slip dynamics. We discuss the response of…

软凝聚态物质 · 物理学 2025-07-30 R. Basak , R. Kozlowski , L. A. Pugnaloni , M. Kramar , E. S. Socolar , C. M. Carlevaro , L. Kondic

Twisted two-dimensional (2D) layered materials exhibit many novel and unique phenomena, such as insulation and superconductivity transition, and superlubricity. However, the effect of twisting on these phenomena remains unclear. A key…

介观与纳米尺度物理 · 物理学 2019-11-26 Ze Liu

We investigate the folding and forced-unbinding transitions of adsorbed semiflexible polymer chains using theory and simulations. These processes describe biologically relevant phenomena that include adhesive interactions between proteins…

软凝聚态物质 · 物理学 2007-05-23 V. Barsegov , D. Thirumalai

Myosin II isoforms with varying mechanochemistry and filament size interact with filamentous actin (F-actin) networks to generate contractile forces in cells. How their properties control force production in environments with varying…

亚细胞过程 · 定量生物学 2014-07-09 Samantha Stam , Jon Alberts , Margaret L. Gardel , Edwin Munro

Although realizing wetting transitions of droplets spontaneously on solid rough surfaces is quite challenging, it is becoming a key research topic in many practical applications which require highly efficient removal of liquid. We report…

软凝聚态物质 · 物理学 2015-06-30 Cunjing Lv , Pengfei Hao , Xiwen Zhang , Feng He

The chemical step is an elementary pattern in chemically heterogeneous substrates, featuring two regions of different wettability separated by a sharp border. Within the framework of lubrication theory, we investigate droplet motion and the…

流体动力学 · 物理学 2026-04-24 Zhuo Long , Peng Gao

The plasma-material interactions present in multiple fusion and propulsion concepts between the flow of plasma through a channel and a material wall drive the emission of secondary electrons. This emission is capable of altering the…

等离子体物理 · 物理学 2024-03-15 Kolter Bradshaw , Bhuvana Srinivasan

An intrinsic feature of nearly all internal interfaces in crystalline systems (homo- and hetero-phase) is the presence of disconnections (topological line defects constrained to the interface that have both step and dislocation character).…

材料科学 · 物理学 2023-05-12 Caihao Qiu , Marco Salvalaglio , David J. Srolovitz , Jian Han

Stochastic simulation has been a powerful tool for studying the dynamics of gene regulatory networks, particularly in terms of understanding how cell-phenotype stability and fate-transitions are impacted by noisy gene expression. However,…

分子网络 · 定量生物学 2018-09-05 Margaret J. Tse , Brian K. Chu , Elizabeth L. Read

Plastic deformation of metals involves the complex evolution of dislocations forming strongly connected dislocation networks. These dislocation networks are based on dislocation reactions, which can form junctions during the interactions of…

材料科学 · 物理学 2022-08-22 Balduin Katzer , Kolja Zoller , Daniel Weygand , Katrin Schulz

In living cells, protein-rich condensates can wet the cell membrane and surfaces of membrane-bound organelles. Interestingly, many phase-separating proteins also bind to membranes leading to a molecular layer of bound molecules. Here we…

生物物理 · 物理学 2022-03-22 Xueping Zhao , Giacomo Bartolucci , Alf Honigmann , Frank Jülicher , Christoph A. Weber

We examined theory for force-induced unbinding on a two-dimensional free energy surface where the internal dynamics of biomolecules is coupled with the rupture process under constant tension f. We show that only if the transition state…

软凝聚态物质 · 物理学 2017-01-24 Changbong Hyeon

The mechanosensitivity of cells, which determines how they are able to respond to mechanical signals received from their environment, is crucial for the functioning of all biological systems. In experiments, cells placed on cyclically…

生物物理 · 物理学 2019-01-17 John J. Molina , Ryoichi Yamamoto

We simulate a two dimensional model of self-propelled particles confined by a deformable boundary. The particles tend to accumulate near the boundary and the shape of the boundary deforms upon the collisions. We find that there are two…

软凝聚态物质 · 物理学 2018-05-18 Wen-de Tian , Yong-kun Guo , Kang Chen , Yu-qiang Ma

How DNA is mapped to functional proteins is a basic question of living matter. We introduce and study a physical model of protein evolution which suggests a mechanical basis for this map. Many proteins rely on large-scale motion to…

生物物理 · 物理学 2017-08-18 Tsvi Tlusty , Albert Libchaber , Jean-Pierre Eckmann

Cell crawling crucially depends on the collective dynamics of the acto-myosin cytoskeleton. However, it remains an open question to what extent cell polarization and persistent motion depend on continuous regulatory mechanisms and…

生物物理 · 物理学 2023-08-11 Fenna Stegemerten , Karin John , Uwe Thiele

Substrate defects crucially influence the onset of sliding drop motion under lateral driving. A finite force is necessary to overcome the pinning influence even of microscale heterogeneities. The depinning dynamics of three-dimensional…

流体动力学 · 物理学 2013-03-25 Ph. Beltrame , P. Hänggi , U. Thiele