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Modeling sequential patterns from data is at the core of various time series forecasting tasks. Deep learning models have greatly outperformed many traditional models, but these black-box models generally lack explainability in prediction…

机器学习 · 计算机科学 2023-05-23 Yingtao Luo , Chang Xu , Yang Liu , Weiqing Liu , Shun Zheng , Jiang Bian

Partial differential equations (PDEs) are central to describing and modelling complex physical systems that arise in many disciplines across science and engineering. However, in many realistic applications PDE modelling provides an…

机器学习 · 计算机科学 2023-04-04 Nacime Bouziani , David A. Ham

In this paper, we investigate the stochastic evolution equations (SEEs) driven by $\log$-Whittle-Mat$\acute{{\mathrm{e}}}$rn (W-M) random diffusion coefficient field and $Q$-Wiener multiplicative force noise. First, the well-posedness of…

数值分析 · 数学 2022-07-05 X. Qi , M. Azaiez , C. Huang , C. Xu

Partial Differential Equations (PDEs) with high dimensionality are commonly encountered in computational physics and engineering. However, finding solutions for these PDEs can be computationally expensive, making model-order reduction…

This review examines the current state of research on microscale cellular changes during the drying of plant-based food materials (PBFM), with particular emphasis on computational modelling approaches. The review addresses the critical need…

机器学习 · 计算机科学 2025-01-17 C. P. Batuwatta-Gamage , H. Jeong , HCP Karunasena , M. A. Karim , C. M. Rathnayaka , Y. T. Gu

Single-particle traces of the diffusive motion of molecules, cells, or animals are by-now routinely measured, similar to stochastic records of stock prices or weather data. Deciphering the stochastic mechanism behind the recorded dynamics…

统计力学 · 物理学 2023-09-14 Henrik Seckler , Janusz Szwabinski , Ralf Metzler

We provide a review of recent advancements in nonlocal continuous models for migration, mainly from the perspective of its involvement in embryonal development and cancer invasion. Particular emphasis is placed on spatial nonlocality…

偏微分方程分析 · 数学 2019-11-14 Li Chen , Kevin Painter , Christina Surulescu , Anna Zhigun

Density functional theory (DFT) has become a standard tool for the study of point defects in materials. However, finding the most stable defective structures remains a very challenging task as it involves the solution of a multimodal…

材料科学 · 物理学 2020-11-16 Marco Arrigoni , Georg K. H. Madsen

Enzyme is the major workhorse to carry out the diverse cellular functions. It catalyzes the biological reactions with a high specificity, with its topology playing a crucial role. For ecologically safe production of numerous bioproducts…

生物大分子 · 定量生物学 2021-06-04 Prabha Sankara Narayanan , Ashish Runthala

Partial Differential Equations (PDEs) describe phenomena ranging from turbulence and epidemics to quantum mechanics and financial markets. Despite recent advances in computational science, solving such PDEs for real-world applications…

Mathematical models describing the spatial spreading and invasion of populations of biological cells are often developed in a continuum modelling framework using reaction-diffusion equations. While continuum models based on linear diffusion…

元胞自动机与格子气 · 物理学 2024-01-23 Matthew J Simpson , Keeley M Murphy , Scott W McCue , Pascal R Buenzli

Causal discovery is a data-driven paradigm for analyzing complex systems, while physics-based models, such as ordinary differential equations (ODEs), provide mechanistic structure for real-world dynamical processes. Integrating these…

机器学习 · 计算机科学 2026-05-21 Jianhong Chen , Naichen Shi , Xubo Yue

Many physical processes can be expressed through partial differential equations (PDEs). Real-world measurements of such processes are often collected at irregularly distributed points in space, which can be effectively represented as…

机器学习 · 计算机科学 2025-07-16 Jost Arndt , Utku Isil , Michael Detzel , Wojciech Samek , Jackie Ma

Discovering hidden partial differential equations (PDEs) and operators from data is an important topic at the frontier between machine learning and numerical analysis. This doctoral thesis introduces theoretical results and deep learning…

数值分析 · 数学 2022-10-31 Nicolas Boullé

Organisms use specialized sensors to measure their environments, but the fundamental principles that determine their accuracy remain largely unknown. In Escherichia coli chemotaxis, we previously found that gradient-climbing speed is…

We propose a model of chemostat where the bacterial population is individually-based, each bacterium is explicitly represented and has a mass evolving continuously over time. The substrate concentration is represented as a conventional…

概率论 · 数学 2013-11-08 Fabien Campillo , Coralie Fritsch

The advancement of human healthspan and bioengineering relies heavily on predicting the behavior of complex biological systems. While high-throughput multiomics data is becoming increasingly abundant, converting this data into actionable…

机器学习 · 计算机科学 2025-12-10 Udesh Habaraduwa , Andrei Lixandru

We study the movement of the living organism in a band form towards the presence of chemical substrate based on a system of partial differential evolution equations. We incorporate the Einstein's method of Brownian motion to deduce the…

动力系统 · 数学 2022-02-01 Rahnuma Islam , Akif Ibragimov

We present a discrete model of chemotaxis whereby cells responding to a chemoattractant are seen as individual agents whose movement is described through a set of rules that result in a biased random walk. In order to take into account…

偏微分方程分析 · 数学 2020-03-27 Federica Bubba , Tommaso Lorenzi , Fiona R Macfarlane

Immune cells have evolved to recognize and eliminate pathogens, and the efficiency of this process can be measured in a Petri dish. Yet, even if the cells are time-lapse recorded and tracked with high resolution, it is difficult to judge…

定量方法 · 定量生物学 2019-06-21 Claus Metzner
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