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In the intricate architecture of the mammalian central nervous system, neurons form populations. Axonal bundles communicate between these clusters using spike trains. However, these neuron populations' precise encoding and operations have…

神经元与认知 · 定量生物学 2024-01-02 Martin N. P. Nilsson

Coordinating multi-articulated bodies to generate purposeful movement is a formidable computational challenge. Yet the human motor system performs this task robustly in dynamic, uncertain environments, despite noisy and delayed feedback,…

神经元与认知 · 定量生物学 2026-02-24 Alessandro Salatiello

The presence of synchronized clusters in neuron networks is a hallmark of information transmission and processing. The methods commonly used to study cluster synchronization in networks of coupled oscillators ground on simplifying…

动力系统 · 数学 2020-07-09 Matteo Lodi , Fabio Della Rossa , Francesco Sorrentino , Marco Storace

Synaptic integration is a prominent aspect of neuronal information processing. The detailed mechanisms that modulate synaptic inputs determine the computational properties of any given neuron. We study a simple model for the summation of…

神经元与认知 · 定量生物学 2021-07-15 Adrian Joseph Alva , Harjinder Singh

Understanding the inner workings of neural networks is essential for enhancing model performance and interpretability. Current research predominantly focuses on examining the connection between individual neurons and the model's final…

计算机视觉与模式识别 · 计算机科学 2025-02-25 Tue M. Cao , Nhat X. Hoang , Hieu H. Pham , Phi Le Nguyen , My T. Thai

Cognition is supported by neurophysiological processes that occur both in local anatomical neighborhoods and in distributed large-scale circuits. Recent evidence from network control theory suggests that white matter pathways linking…

神经元与认知 · 定量生物学 2016-06-30 John D. Medaglia , Shi Gu , Fabio Pasqualetti , Rebecca L. Ashare , Caryn Lerman , Joseph Kable , Danielle S. Bassett

The extraordinary computational power of the brain may be related in part to the fact that each of the smaller neural networks that compose it can behave transiently in many different ways, depending on its inputs. Mathematically, input…

神经元与认知 · 定量生物学 2008-03-29 Léonard Gérard , Jean-Jacques Slotine

Cognitive control is a suite of processes that helps individuals pursue goals despite resistance or uncertainty about what to do. Although cognitive control has been extensively studied as a dynamic feedback loop of perception, valuation,…

This paper proposes a neuronal circuitry layout and synaptic plasticity principles that allow the (pyramidal) neuron to act as a "combinatorial switch". Namely, the neuron learns to be more prone to generate spikes given those combinations…

生物物理 · 物理学 2017-05-09 Marat M. Rvachev

We review how sensorimotor control is dictated by interacting neural populations, optimal feedback mechanisms, and the biomechanics of bodies. First, we outline the distributed anatomical loops that shuttle sensorimotor signals between…

神经元与认知 · 定量生物学 2025-09-19 Muhammad Noman Almani , John Lazzari , Jeff Walker , Shreya Saxena

Working memory often appears to exceed its basic span by organizing items into compact representations called chunks. Chunking can be learned over time for familiar inputs; however, it can also arise spontaneously for novel stimuli. Such…

神经元与认知 · 定量生物学 2025-09-19 Weishun Zhong , Mikhail Katkov , Misha Tsodyks

Motor control requires sensory feedback, and the nature of this feedback has implications for the tasks of the central nervous system (CNS): for an approximately linear mechanical system (e.g., a freely standing person, a rider on a…

神经元与认知 · 定量生物学 2025-04-24 Eric Maris

The principles of neural encoding and computations are inherently collective and usually involve large populations of interacting neurons with highly correlated activities. While theories of neural function have long recognized the…

神经元与认知 · 定量生物学 2019-05-14 Christophe Gardella , Olivier Marre , Thierry Mora

As a follow-up tutorial article of [29], in this paper, we will introduce the basic compositional units of the human brain, which will further illustrate the cell-level bio-structure of the brain. On average, the human brain contains about…

神经元与认知 · 定量生物学 2019-06-06 Jiawei Zhang

The problem of the transformation of microscopic information to the macroscopic level is an intriguing challenge in computational neuroscience, but also of general mathematical importance. Here, a phenomenological mathematical model is…

泛函分析 · 数学 2009-06-19 Hamid Reza Noori

It is largely believed that complex cognitive phenomena require the perfect orchestrated collaboration of many neurons. However, this is not what converging experimental evidence suggests. Single neurons, the so-called concept cells, may be…

神经元与认知 · 定量生物学 2019-12-05 Carlos Calvo Tapia , Ivan Tyukin , Valeri A. Makarov

A hallmark of biological intelligence and control is combinatorial generalization: animals are able to learn various things, then piece them together in new combinations to produce appropriate outputs for new tasks. Inspired by the ability…

神经元与认知 · 定量生物学 2022-10-07 Sunny Duan , Mikail Khona , Adrian Bertagnoli , Sarthak Chandra , Ila Fiete

Accurate and robust recording and decoding from the central nervous system (CNS) is essential for advances in human-machine interfacing. However, technologies used to directly measure CNS activity are limited by their resolution,…

神经元与认知 · 定量生物学 2025-09-19 Jaime Ibáñez , Blanka Zicher , Etienne Burdet , Stuart N. Baker , Carsten Mehring , Dario Farina

Stylized models of the neurodynamics that underpin sensory motor control in animals are proposed and studied. The voluntary motions of animals are typically initiated by high level intentions created in the primary cortex through a…

系统与控制 · 电气工程与系统科学 2021-10-12 John Baillieul , Zexin Sun

When a neuron fires and the resulting action potential travels down its axon toward other neurons' dendrites, the effect on each of those neurons is mediated by the weight of the synapse that separates it from the firing neuron. This…

神经元与认知 · 定量生物学 2010-02-19 Andre Nathan , Valmir C. Barbosa
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