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Cancer screening, leading to early detection, saves lives. Unfortunately, existing screening techniques require expensive and intrusive medical procedures, not globally available, resulting in too many lost would-be-saved lives. We present…

机器学习 · 计算机科学 2025-09-29 Liwen Sun , Hao-Ren Yao , Gary Gao , Ophir Frieder , Chenyan Xiong

Rapidly dividing tissues, like intestinal crypts, are frequently chosen to investigate the process of tumor initiation, because of their high rate of mutations. To study the interplay between normal and mutant as well as immortal cells in…

组织与器官 · 定量生物学 2016-11-09 Ali Mahdipour Shirayeh , Leili Shahriyari

Heart failure (HF) is a leading cause of morbidity, mortality, and health care costs. Prolonged conduction through the myocardium can occur with HF, and a device-driven approach, termed cardiac resynchronization therapy (CRT), can improve…

机器学习 · 计算机科学 2021-09-14 Brendan E. Odigwe , Francis G. Spinale , Homayoun Valafar

Nuclear detection, segmentation and morphometric profiling are essential in helping us further understand the relationship between histology and patient outcome. To drive innovation in this area, we setup a community-wide challenge using…

Most early-stage colorectal cancer (CRC) patients can be cured by surgery alone, and only certain high-risk early-stage CRC patients benefit from adjuvant chemotherapies. However, very few validated biomarkers are available to accurately…

机器学习 · 计算机科学 2021-11-08 Xingyu Li , Jitendra Jonnagaddala , Shuhua Yang , Hong Zhang , Xu Steven Xu

Brain tumor is a life-threatening problem and hampers the normal functioning of the human body. The average five-year relative survival rate for malignant brain tumors is 35.6 percent. For proper diagnosis and efficient treatment planning,…

图像与视频处理 · 电气工程与系统科学 2024-07-16 Vidhyapriya Ranganathan , Celshiya Udaiyar , Jaisree Jayanth , Meghaa P , Srija B , Uthra S

Colorectal cancer, largely arising from precursor lesions called polyps, remains one of the leading causes of cancer-related death worldwide. Current clinical standards require the resection and histopathological analysis of polyps due to…

图像与视频处理 · 电气工程与系统科学 2020-01-13 Rodney LaLonde , Pujan Kandel , Concetto Spampinato , Michael B. Wallace , Ulas Bagci

Background: Effective allocation of limited donor lungs in cystic fibrosis (CF) requires accurate survival predictions, so that high-risk patients may be prioritized for transplantation. In practice, decisions about allocation are made…

Colonoscopy is currently one of the most sensitive screening methods for colorectal cancer. This study investigates the frontiers of intelligent colonoscopy techniques and their prospective implications for multimodal medical applications.…

图像与视频处理 · 电气工程与系统科学 2025-09-25 Ge-Peng Ji , Jingyi Liu , Peng Xu , Nick Barnes , Fahad Shahbaz Khan , Salman Khan , Deng-Ping Fan

Pancreatic cancer is one of the global leading causes of cancer-related deaths. Despite the success of Deep Learning in computer-aided diagnosis and detection (CAD) methods, little attention has been paid to the detection of Pancreatic…

计算机视觉与模式识别 · 计算机科学 2022-08-09 Christiaan G. A. Viviers , Mark Ramaekers , Peter H. N. de With , Dimitrios Mavroeidis , Joost Nederend , Misha Luyer , Fons van der Sommen

With nearly one million new cases diagnosed worldwide in 2020, head \& neck cancer is a deadly and common malignity. There are challenges to decision making and treatment of such cancer, due to lesions in multiple locations and outcome…

图像与视频处理 · 电气工程与系统科学 2023-05-17 Angel Victor Juanco Muller , Joao F. C. Mota , Keith A. Goatman , Corne Hoogendoorn

Treatment approaches for colorectal cancer (CRC) are highly dependent on the molecular subtype, as immunotherapy has shown efficacy in cases with microsatellite instability (MSI) but is ineffective for the microsatellite stable (MSS)…

计算机视觉与模式识别 · 计算机科学 2024-11-13 Hadar Hezi , Matan Gelber , Alexander Balabanov , Yosef E. Maruvka , Moti Freiman

Bladder cancer is one of the most prevalent malignancies worldwide, with a recurrence rate of up to 78%, necessitating accurate post-operative monitoring for effective patient management. Multi-sequence contrast-enhanced MRI is commonly…

计算机视觉与模式识别 · 计算机科学 2025-11-20 Xueyang Li , Zongren Wang , Yuliang Zhang , Zixuan Pan , Yu-Jen Chen , Nishchal Sapkota , Gelei Xu , Danny Z. Chen , Yiyu Shi

The uncontrolled and unstructured growth of brain cells is known as brain tumor, which has one of the highest mortality rates among diseases from all types of cancers. Due to limited diagnostic and treatment capabilities, they pose…

机器学习 · 计算机科学 2024-04-02 PoTsang B. Huang , Muhammad Rizwan , Mehboob Ali

Multimodal prehabilitation for colorectal cancer (CRC) surgery aims to optimize patient fitness and reduce postoperative complications. While telemonitoring's clinical value in supporting decision-making is recognized, patient perspectives…

Colorectal cancer (CRC) poses a major public health challenge due to its increasing prevalence, particularly among younger populations. Microsatellite instability-high (MSI-H) CRC and deficient mismatch repair (dMMR) CRC constitute 15% of…

细胞行为 · 定量生物学 2026-05-19 Georgio Hawi , Peter S. Kim , Peter P. Lee

Photon-counting computed tomography (PCCT) marks a significant advancement over conventional energy-integrating detector (EID) CT systems. This review highlights PCCT's superior spatial and contrast resolution, reduced radiation dose, and…

Objectives To develop and validate a deep learning-based diagnostic model incorporating uncertainty estimation so as to facilitate radiologists in the preoperative differentiation of the pathological subtypes of renal cell carcinoma (RCC)…

图像与视频处理 · 电气工程与系统科学 2023-11-14 Ni Yao , Hang Hu , Kaicong Chen , Chen Zhao , Yuan Guo , Boya Li , Jiaofen Nan , Yanting Li , Chuang Han , Fubao Zhu , Weihua Zhou , Li Tian

Pancreatic cancer will soon be the second leading cause of cancer-related death in Western society. Imaging techniques such as CT, MRI and ultrasound typically help providing the initial diagnosis, but histopathological assessment is still…

图像与视频处理 · 电气工程与系统科学 2022-01-26 Pierpaolo Vendittelli , Esther M. M. Smeets , Geert Litjens

Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers, and early detection remains a major clinical challenge due to the absence of specific symptoms and reliable biomarkers. In this work, we propose a new multimodal…