相关论文: Hormonal Factors Moderate the Associations Between…
Objectives: To examine sex differences in the associations between vascular risk factors and 6-year changes in the volume of white matter hyperintensities (WMH), and between changes in WMH volumes and changes in cognitive performance, in a…
Blood Pressure (BP) is a biological signal related to the cardiovascular system that inevitably is affected by ageing. Moreover, it is also influenced by the presence of cardiovascular risk factors. To evaluate how the relationship be-tween…
The Women's Health Initiative randomized clinical trial of hormone therapy found no benefit of hormones in preventive cardiovascular disease, a finding in striking contrast with a large body of observational research. Understanding whether…
Longitudinal biomarker data and cross-sectional outcomes are routinely collected in modern epidemiology studies, often with the goal of informing tailored early intervention decisions. For example, hormones such as estradiol and…
The use of office measurement of Blood Pressure (BP) as well as of the mean on day-time, on night-time or on 24h does not accurately describe the changes of the BP circadian rhythm. Moreover, several risk factors affect this rhythm but…
Background: Higher endogenous testosterone levels are associated with reduced chronic disease risk and mortality. Since the mid-20th century, there have been significant changes in dietary patterns, and men's testosterone levels have…
An experimental study is reported which investigates the wall shear stress (WSS) distribution in a transparent model of the human aorta comparing a bileaflet mechanical heart valve (BMHV) with a trileaflet mechanical heart valve (TMHV) in…
Type 2 diabetes mellitus represents a prevalent and widespread global health concern, necessitating a comprehensive assessment of its risk factors. This study aimed towards learning whether there is any differential impact of age,…
Blood Pressure (BP) and Heart Rate (HR) provide information on clin-ical condition along 24h. Both signals present circadian changes due to sympa-thetic/parasympathetic control system that influence the relationship between them. Moreover,…
The relationship between cognition and white matter hyperintensities (WMH) volumes often depends on the accuracy of the lesion segmentation algorithm used. As such, accurate detection and quantification of WMH is of great interest. Here, we…
Objectives: Stress hormones have been associated with temporal discounting. Although time-discount rate is shown to be stable over a long term, no study to date examines whether individual differences in stress hormones could predict…
Hypertension is a medical condition that is well-established as a risk factor for many major diseases. For example, it can cause alterations in the cardiac structure and function over time that can lead to heart related morbidity and…
White matter hyperintensities (WMH) are a hallmark of cerebrovascular disease and multiple sclerosis. Automated WMH segmentation methods enable quantitative analysis via estimation of total lesion load, spatial distribution of lesions, and…
Hypertensive disorders of pregnancy occur in about 10% of pregnant women around the world. Though there is evidence that hypertension impacts maternal cardiac functions, the relation between hypertension and cardiac dysfunctions is only…
Objectives: The primary purpose of this study is to analyze the relationship between the first occurrence of hospitalization for cardiovascular disease (CVD) and particulate matter less than 2.5 micrometre in diameter (PM2.5) exposure,…
Sex-based differences in cardiovascular disease are well documented, yet the precise nature and extent of these discrepancies in cardiac anatomy remain incompletely understood. Traditional scaling models often fail to capture the interplay…
In this study, we delve into the intricate relationships between diabetes and a range of health indicators, with a particular focus on the newly added variable of income. Utilizing data from the 2015 Behavioral Risk Factor Surveillance…
Heart rate (HR) and its variability (HRV) has been proposed as a marker for depressive symptoms and other aspects of mental health. However, the real correlation between them is presently uncertain, as previous studies have generally been…
Hypertension is a highly prevalent condition and a major risk factor for cardiovascular disease. The landmark Systolic Blood Pressure Intervention Trial (SPRINT) showed that lowering systolic blood pressure (BP) goals from 140 mmHg to 120…
Women are at increased risk of bone loss during the menopausal transition; in fact, nearly 50\% of women's lifetime bone loss occurs during this time. The longitudinal relationships between estradiol (E2) and follicle-stimulating hormone…