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相关论文: Gene expression noise accelerates the evolution of…

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Previous studies in quantum information have recognized that specific types of noise can encode information in certain applications. However, the role of noise in Quantum Hypothesis Testing (QHT), traditionally assumed to undermine…

量子物理 · 物理学 2024-08-06 Qing Li , Lingna Wang , Min Jiang , Ze Wu , Haidong Yuan , Xinhua Peng

This paper augments the existing macroscopic circuit noise model for phase noise in relaxation oscillators by showing the microscopic origins of the noise and explains temperature dependency. The noise arises from fluctuation of the energy…

统计力学 · 物理学 2018-08-16 Y. Ng , B. Leung , M. Kononenko , S. Safavi-Naeini

When biological populations expand into new territory, the evolutionary outcomes can be strongly influenced by genetic drift, the random fluctuations in allele frequencies. Meanwhile, spatial variability in the environment can also…

种群与进化 · 定量生物学 2024-06-27 Jimmy Gonzalez Nuñez , Jayson Paulose , Wolfram Möbius , Daniel A. Beller

We introduce a biologically detailed, stochastic model of gene expression describing the multiple rate-limiting steps of transcription, nuclear pre-mRNA processing, nuclear mRNA export, cytoplasmic mRNA degradation and translation of mRNA…

分子网络 · 定量生物学 2024-01-24 Muhan Ma , Juraj Szavits-Nossan , Abhyudai Singh , Ramon Grima

Regulation of gene expression is the consequence of interactions between the promoter of the gene and the transcription factors (TFs). In this paper, we explore the features of a genetic network where the TFs (activators and repressors)…

分子网络 · 定量生物学 2025-06-05 Amit Kumar Das , Debabrata Biswas

We demonstrate how noise can be turned into an advantage for optical sensing using a nonlinear cavity. The cavity is driven by a continuous wave laser into the regime of optical bistability. Due to the influence of fluctuations, the cavity…

光学 · 物理学 2020-02-19 Said R. K. Rodriguez

We study the long time behaviour of a nonlinear oscillator subject to a random multiplicative noise with a spectral density (or power-spectrum) that decays as a power law at high frequencies. When the dissipation is negligible, physical…

混沌动力学 · 物理学 2009-11-13 Kirone Mallick

The dynamics of adaptation is difficult to predict because it is highly stochastic even in large populations. The uncertainty emerges from number fluctuations, called genetic drift, arising in the small number of particularly fit…

种群与进化 · 定量生物学 2015-06-30 Oskar Hallatschek , Lukas Geyrhofer

Delay is an inherent feature of genetic regulatory networks. It represents the time required for the assembly of functional regulator proteins. The protein production process is complex, as it includes transcription, translocation,…

亚细胞过程 · 定量生物学 2025-12-29 Sean Campbell , Courtney C. White , Amanda M. Alexander , William Ott

After being considered as a nuisance to be filtered out, it became recently clear that biochemical noise plays a complex role, often fully functional, for a genetic network. The influence of intrinsic and extrinsic noises on genetic…

分子网络 · 定量生物学 2015-06-05 Giulio Caravagna , Giancarlo Mauri , Alberto d'Onofrio

Genetically identical cells in the same population can take on phenotypically variable states, leading to differentiated responses to external signals, such as nutrients and drug-induced stress. Many models and experiments have focused on a…

分子网络 · 定量生物学 2015-04-28 Thierry Mora , Aleksandra M. Walczak

We study the effects of the sequence on the propagation of nonlinear excitations in simple models of DNA, and how those effects are modified by noise. Starting from previous results on soliton dynamics on lattices defined by aperiodic…

生物大分子 · 定量生物学 2009-11-10 Sara Cuenda , Angel Sanchez

Noise, through its interaction with the nonlinearity of the living systems, can give rise to counter-intuitive phenomena such as stochastic resonance, noise-delayed extinction, temporal oscillations, and spatial patterns. In this paper we…

种群与进化 · 定量生物学 2007-05-23 B. Spagnolo , D. Valenti , A. Fiasconaro

Predator-prey models have been shown to exhibit resonance-like behaviour, in which random fluctuations in the number of organisms (demographic noise) are amplified when their frequency is close to the natural oscillatory frequency of the…

统计力学 · 物理学 2023-02-01 Marios Giannakou , Bartlomiej Waclaw

Stochasticity (or noise) at cellular and molecular levels has been observed extensively as a universal feature for living systems. However, how living systems deal with noise while performing desirable biological functions remains a major…

分子网络 · 定量生物学 2020-01-22 Qing Nie , Lingxia Qiao , Yuchi Qiu , Lei Zhang , Wei Zhao

Stochastic resonance is a non-linear phenomenon, in which the sensitivity of signal detectors can be enhanced by adding random noise to the detector input. Here, we demonstrate that noise can also improve the information flux in recurrent…

神经元与认知 · 定量生物学 2018-11-30 Patrick Krauss , Karin Prebeck , Achim Schilling , Claus Metzner

The effects of carrying capacity of environment $K$ for degradation (the $K$ effect for short) on the constitutive gene expression and a simple genetic regulation system, are investigated by employing a stochastic Langevin equation combined…

生物物理 · 物理学 2020-05-20 Yan-Ling Feng , Jing Sun , Yi-Fan Liu , Jian-Gong Ren , Jian-Min Dong

We examine the effect of noise on societies of agents using an agent-based model of evolutionary norm emergence. Generally, we see that noisy societies are more selfish, smaller and discontent, and are caught in rounds of perpetual…

多智能体系统 · 计算机科学 2024-11-28 Stavros Anagnou , Daniel Polani , Christoph Salge

Gene expression is inherently noisy, posing a challenge to understanding how precise and reproducible patterns of gene expression emerge in mammals. We investigate this phenomenon using gastruloids, an in vitro model for early mammalian…

细胞行为 · 定量生物学 2025-11-19 Melody Merle , Leah Friedman , Corinne Chureau , Armin Shoushtarizadeh , Thomas Gregor

Evolution of genetic code is studied as the change in the choice of enzymes that are used to synthesize amino acids from the genetic information of nucleic acids. We propose the following theory: the differentiation of physiological states…

适应与自组织系统 · 物理学 2007-05-23 H. Takagi , K. Kaneko , T. Yomo
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