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Chronic upper extremity (UE) impairment is common after stroke. This study evaluated Boost, a novel wheelchair-mounted rehabilitation device designed to assist individuals in UE motor recovery during inpatient rehabilitation. Thirty-five…

This study investigates the sleep characteristics and brain activity of individuals in the gray zone of insomnia, a population that experiences sleep disturbances yet does not fully meet the clinical criteria for chronic insomnia. Thirteen…

人机交互 · 计算机科学 2024-11-18 Ha-Na Jo , Young-Seok Kweon , Seo-Hyun Lee

Electroencephalogram (EEG) monitoring and objective seizure identification is an essential clinical investigation for some patients with epilepsy. Accurate annotation is done through a time-consuming process by EEG specialists.…

医学物理 · 物理学 2021-04-22 Yikai Yang , Nhan Duy Truong , Christina Maher , Armin Nikpour , Omid Kavehei

Identifying abnormal electroencephalographic activity is crucial in diagnosis and treatment of epilepsy. Recent studies showed that decomposing brain activity into periodic (oscillatory) and aperiodic (trend across all frequencies)…

Background: Recent systematic reviews of randomised controlled trials (RCTs) in relapsing multiple sclerosis (RMS) revealed a decrease in placebo annualized relapse rates (ARR) over the past two decades. Furthermore, regression to the mean…

应用统计 · 统计学 2015-09-03 Christian Röver , Richard Nicholas , Sebastian Straube , Tim Friede

Mental disorders present challenges in diagnosis and treatment due to their complex and heterogeneous nature. Electroencephalogram (EEG) has shown promise as a potential biomarker for these disorders. However, existing methods for analyzing…

统计方法学 · 统计学 2024-01-30 Xingche Guo , Bin Yang , Ji Meng Loh , Qinxia Wang , Yuanjia Wang

We present SeizureFormer, a Transformer-based model for long-term seizure risk forecasting using interictal epileptiform activity (IEA) surrogate biomarkers and long episode (LE) biomarkers from responsive neurostimulation (RNS) systems.…

信号处理 · 电气工程与系统科学 2025-05-12 Tianning Feng , Juntong Ni , Ezequiel Gleichgerrcht , Wei Jin

Background: Dementia, marked by cognitive decline, is a global health challenge. Alzheimer's disease (AD), the leading type, accounts for ~70% of cases. Electroencephalography (EEG) measures show promise in identifying AD risk, but…

信号处理 · 电气工程与系统科学 2024-11-28 Veronica Henao Isaza , David Aguillon , Carlos Andres Tobon Quintero , Francisco Lopera , John Fredy Ochoa Gomez

Epilepsy represents the most prevalent neurological disease in the world. One-third of people suffering from mesial temporal lobe epilepsy (MTLE) exhibit drug resistance, urging the need to develop new treatments. A key part in anti-seizure…

Epilepsy is the second most common brain disorder after migraine. Automatic detection of epileptic seizures can considerably improve the patients' quality of life. Current Electroencephalogram (EEG)-based seizure detection systems encounter…

信号处理 · 电气工程与系统科学 2018-03-28 Ramy Hussein , Hamid Palangi , Rabab Ward , Z. Jane Wang

We consider the problem of individual-specific medication level recommendation (initiation, removal, increase, or decrease) for asthma sufferers. Asthma is one of the most common chronic diseases in both adults and children, affecting 8% of…

应用统计 · 统计学 2017-05-22 Curtis B Storlie , Megan E Branda , Michael R Gionfriddo , Nilay D Shah , Matthew A Rank

Neocortical epilepsy surgery fails to achieve post-operative seizure freedom in 30-40% of cases. It is not fully understood why surgery in some patients is unsuccessful. Comparing interictal MEG bandpower from patients to normative maps,…

Amyotrophic lateral sclerosis is a fatal disease that not only affects movement, speech, and breath but also cognition. Recent studies have focused on the use of language analysis techniques to detect ALS and infer scales for monitoring…

计算与语言 · 计算机科学 2023-09-14 Carla Agurto , Guillermo Cecchi , Bo Wen , Ernest Fraenkel , James Berry , Indu Navar , Raquel Norel

Epilepsy is a chronic neurological disorder that affects a significant portion of the human population and imposes serious risks in the daily life of patients. Despite advances in machine learning and IoT, small, nonstigmatizing wearable…

机器学习 · 计算机科学 2023-02-22 Una Pale , Tomas Teijeiro , David Atienza

Neurological disorders, including stroke, spinal cord injuries, multiple sclerosis, and Parkinson's disease, generally lead to diminished upper extremity (UE) function, impacting individuals' independence and quality of life. Traditional…

信号处理 · 电气工程与系统科学 2024-08-02 Tommaso Proietti , Andrea Bandini

Background: Anti-seizure medications (ASMs) can reduce seizure duration, but their precise modes of action are unclear. Specifically, it is unknown whether ASMs shorten seizures by simply compressing existing seizure activity into a shorter…

Brain parenchymal fraction (BPF) has been used as a surrogate measure of global brain atrophy, and as a biomarker of brain reserve in studies evaluating clinical outcomes after brain injury. Total brain volume at the time of injury has…

神经元与认知 · 定量生物学 2024-03-20 Kenda Alhadid , Robert W. Regenhardt , Natalia S. Rost , Markus D. Schirmer

Background: Investigation of the functioning of the brain in living systems has been a major effort amongst scientists and medical practitioners. Amongst the various disorder of the brain, epilepsy has drawn the most attention because this…

医学物理 · 物理学 2009-08-03 Md. Nurujjaman , Ramesh Naryanan , A. N. Sekar Iyengar

Epilepsy is one of the most prevalent brain disorders that disrupts the lives of millions worldwide. For patients with drug-resistant seizures, there exist implantable devices capable of monitoring neural activity, promptly triggering…

信号处理 · 电气工程与系统科学 2023-10-31 Arman Zarei , Bingzhao Zhu , Mahsa Shoaran

This study assessed the safety, feasibility, and acceptability of a novel device to monitor ischaemic stroke patients. The device captured electroencephalography (EEG) and electrocardiography (ECG) data to compute an ECG-based metric termed…