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Propensity score (PS) methods are widely used to estimate treatment effects in non-randomized studies. Variance is typically estimated using sandwich or bootstrap methods, which can either treat the PS as estimated or fixed. The latter is…

统计方法学 · 统计学 2025-11-17 Baoshan Zhang , Sean M. O'Brien , Yuan Wu , Laine E. Thomas

Clustering and dependence are common in trials. For example, in some cluster randomized trials (CRTs), pre-existing clusters are enrolled, randomized, and serve as the basis of intervention delivery. Such CRTs are "fully clustered":…

Covariate adjustment aims to improve the statistical efficiency of randomized trials by incorporating information from baseline covariates. Popular methods for covariate adjustment include analysis of covariance for continuous endpoints and…

统计方法学 · 统计学 2025-05-09 Zhiwei Zhang , Ya Wang , Dong Xi

Win statistics have become increasingly popular for analyzing hierarchical composite endpoints in clinical trials, because they summarize treatment benefit through pairwise comparisons that respect the clinical importance order among…

统计方法学 · 统计学 2026-04-21 Xi Fang , Guangyu Tong , Yuan Huang , F. Perry Wilson , Patrick J. Heagerty , Fan Li

We consider the problem of conditional independence testing: given a response Y and covariates (X,Z), we test the null hypothesis that Y is independent of X given Z. The conditional randomization test (CRT) was recently proposed as a way to…

统计方法学 · 统计学 2021-06-07 Molei Liu , Eugene Katsevich , Lucas Janson , Aaditya Ramdas

Shape-restricted inferences have exhibited empirical success in various applications with survival data. However, certain works fall short in providing a rigorous theoretical justification and an easy-to-use variance estimator with…

统计理论 · 数学 2024-07-10 Junjun Lang , Yukun Liu , Jing Qin

Randomized controlled trials (RCTs) face inherent limitations, such as ethical or resource constraints, which lead to a limited number of study participants. To address these limitations, recent research endeavors have sought to incorporate…

统计方法学 · 统计学 2025-02-20 Peijin Wang , Hwanhee Hong , Kyungeun Jeon , Laine Elliott Thomas

We describe how to calculate standard errors for A/B tests that include clustered data, ratio metrics, and/or covariate adjustment. We may do this for power analysis/sample size calculations prior to running an experiment using historical…

统计方法学 · 统计学 2024-06-12 Tim Hesterberg , Ben Knight

Microbial communities analysis is drawing growing attention due to the rapid development of high-throughput sequencing techniques nowadays. The observed data has the following typical characteristics: it is high-dimensional, compositional…

统计方法学 · 统计学 2020-04-30 Yong He , Pengfei Liu , Xinsheng Zhang , Wang Zhou

The instability in the selection of models is a major concern with data sets containing a large number of covariates. This paper deals with variable selection methodology in the case of high-dimensional problems where the response variable…

应用统计 · 统计学 2012-03-23 Marie Walschaerts , Eve Leconte , Philippe Besse

Minimum Bayes-risk (MBR) decoding has recently gained renewed attention in text generation. MBR decoding considers texts sampled from a model as pseudo-references and selects the text with the highest similarity to the others. Therefore,…

计算与语言 · 计算机科学 2024-04-02 Atsumoto Ohashi , Ukyo Honda , Tetsuro Morimura , Yuu Jinnai

We study inference for linear quantile regression with two-way clustered data. Using a separately exchangeable array framework and a projection decomposition of the quantile score, we characterize regime-dependent convergence rates and…

计量经济学 · 经济学 2026-05-26 Ulrich Hounyo , Jiahao Lin

The restricted mean survival time (RMST) is the mean survival time in the study population followed up to a specific time point, and is simply the area under the survival curve up to the specific time point. The difference between two RMSTs…

统计方法学 · 统计学 2025-09-18 Peter Zhang , Brent Logan , Michael Martens

In randomized experiments, covariates are often used to reduce variance and improve the precision of treatment effect estimates. However, in many real-world settings, interference between units, where one unit's treatment affects another's…

统计方法学 · 统计学 2026-04-10 Xinyi Wang , Shuangning Li

There are multiple cluster randomised trial designs that vary in when the clusters cross between control and intervention states, when observations are made within clusters, and how many observations are made at that time point. Identifying…

统计方法学 · 统计学 2023-07-20 Samuel I. Watson , Alan Girling , Karla Hemming

Variance reduction for causal inference in the presence of network interference is often achieved through either outcome modeling, typically analyzed under unit-randomized Bernoulli designs, or clustered experimental designs, typically…

统计方法学 · 统计学 2026-01-19 Matthew Eichhorn , Samir Khan , Johan Ugander , Christina Lee Yu

Survey instruments and assessments are frequently used in many domains of social science. When the constructs that these assessments try to measure become multifaceted, multidimensional item response theory (MIRT) provides a unified…

统计方法学 · 统计学 2025-01-08 Chenchen Ma , Jing Ouyang , Chun Wang , Gongjun Xu

Clustered sampling is prevalent in empirical regression discontinuity (RD) designs, but it has not received much attention in the theoretical literature. In this paper, we introduce a general model-based framework for such settings and…

计量经济学 · 经济学 2026-03-20 Claudia Noack , Tomasz Olma , Christoph Rothe

Reliable uncertainty quantification is essential for deploying machine learning systems in high-stakes domains. Conformal prediction provides distribution-free coverage guarantees but often produces overly large prediction sets, limiting…

机器学习 · 计算机科学 2026-04-28 Yunpeng Xu , Wenge Guo , Zhi Wei

The micro-randomized trial (MRT) is a sequential randomized experimental design to empirically evaluate the effectiveness of mobile health (mHealth) intervention components that may be delivered at hundreds or thousands of decision points.…

统计方法学 · 统计学 2021-12-14 Jieru Shi , Zhenke Wu , Walter Dempsey