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The conditional randomization test (CRT) was recently proposed to test whether two random variables X and Y are conditionally independent given random variables Z. The CRT assumes that the conditional distribution of X given Z is known…

机器学习 · 计算机科学 2023-04-11 Shuai Li , Ziqi Chen , Hongtu Zhu , Christina Dan Wang , Wang Wen

Adaptive sample size re-estimation, early stopping, and trial re-design at interim analyses can reduce expected sample sizes in randomised trials. Cluster randomised trials, in which groups of participants are randomly allocated to…

统计方法学 · 统计学 2026-03-09 Samuel I. Watson , James Martin

The manuscript discusses how to incorporate random effects for quantile regression models for clustered data with focus on settings with many but small clusters. The paper has three contributions: (i) documenting that existing methods may…

统计方法学 · 统计学 2022-02-24 Maria Laura Battagliola , Helle Sørensen , Anders Tolver , Ana-Maria Staicu

Randomized benchmarking (RB) is an efficient and robust method to characterize gate errors in quantum circuits. Averaging over random sequences of gates leads to estimates of gate errors in terms of the average fidelity. These estimates are…

量子物理 · 物理学 2019-09-11 Jonas Helsen , Joel J. Wallman , Steven T. Flammia , Stephanie Wehner

The most popular approach for analyzing survival data is the Cox regression model. The Cox model may, however, be misspecified, and its proportionality assumption may not always be fulfilled. An alternative approach for survival prediction…

机器学习 · 统计学 2018-05-17 Marvin N. Wright , Theresa Dankowski , Andreas Ziegler

We consider applying stochastic approximation (SA) methods to solve nonsmooth variational inclusion problems. Existing studies have shown that the averaged iterates of SA methods exhibit asymptotic normality, with an optimal limiting…

Machine-learning systems used in survey-based social measurement require uncertainty estimates that are reliable across population subgroups, not merely valid in aggregate. We study ordinal conformal prediction for five-level AI-attitude…

统计方法学 · 统计学 2026-05-08 Amir Rafe , Subasish Das

Relative Validity Indices (RVIs) such as the Silhouette Width Criterion and Davies Bouldin indices are the most widely used tools for evaluating and optimising clustering outcomes. Traditionally, their ability to rank collections of…

Clustered standard errors and approximate randomization tests are popular inference methods that allow for dependence within observations. However, they require researchers to know the cluster structure ex ante. We propose a procedure to…

计量经济学 · 经济学 2022-01-14 Yong Cai

Sequence-to-Sequence (seq2seq) tasks transcribe the input sequence to a target sequence. The Connectionist Temporal Classification (CTC) criterion is widely used in multiple seq2seq tasks. Besides predicting the target sequence, a side…

计算与语言 · 计算机科学 2023-02-01 Jinchuan Tian , Brian Yan , Jianwei Yu , Chao Weng , Dong Yu , Shinji Watanabe

It is often of interest to study the association between covariates and the cumulative incidence of a right-censored time-to-event outcome. When time-varying covariates are measured on a fixed discrete time scale, it is desirable to account…

统计方法学 · 统计学 2026-04-28 Hongxiang Qiu , Marco Carone , Alex Luedtke , Peter B. Gilbert

Although there is much excitement surrounding the use of mobile and wearable technology for the purposes of delivering interventions as people go through their day-to-day lives, data analysis methods for constructing and optimizing digital…

Cox proportional hazard regression model is a popular tool to analyze the relationship between a censored lifetime variable with other relevant factors. The semi-parametric Cox model is widely used to study different types of data arising…

统计方法学 · 统计学 2018-10-09 Abhik Ghosh , Ayanendranath Basu

A/B testing is a standard approach for evaluating the effect of online experiments; the goal is to estimate the `average treatment effect' of a new feature or condition by exposing a sample of the overall population to it. A drawback with…

社会与信息网络 · 计算机科学 2013-05-31 Johan Ugander , Brian Karrer , Lars Backstrom , Jon Kleinberg

Objectives: This study aims to characterize the dose-performance relationship for opportunistic CT and disentangle the contributions of segmentation failure and dose-dependent HU bias to performance degradation. Methods: Simulated low-dose…

Background: In settings where proof-of-principle trials have succeeded but the effectiveness of different forms of implementation remains uncertain, trials that not only generate information about intervention effects but also provide…

定量方法 · 定量生物学 2017-05-16 Guy Harling , Rui Wang , Jukka-Pekka Onnela , Victor De Gruttola

Recent observations, especially in cancer immunotherapy clinical trials with time-to-event outcomes, show that the commonly used proportial hazard assumption is often not justifiable, hampering an appropriate analyse of the data by hazard…

统计方法学 · 统计学 2021-02-23 Marc Ditzhaus , Menggang Yu , Jin Xu

Semiparametric estimators admitting a von Mises expansion often reduce inference to the influence-function variance. This reduction is justified when the second-order remainder is negligible in variance, a condition that is stronger than…

统计方法学 · 统计学 2026-05-26 Lin Li , Pengcheng Wu

For toxicology studies, the validation of the concurrent control group by historical control data (HCD) has become requirements. This validation is usually done by historical control limits (HCL), which should cover the observations of the…

应用统计 · 统计学 2025-07-18 Max Menssen , Jonathan Rathjens

Cluster randomized trials (CRTs) with multiple unstructured mediators present significant methodological challenges for causal inference due to within-cluster correlation, interference among units, and the complexity introduced by multiple…

统计方法学 · 统计学 2025-04-21 Yuki Ohnishi , Fan Li
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