相关论文: Parameter estimation and model reduction for retin…
We consider the inverse problem of fitting atmospheric dispersion parameters based on time-resolved back-scattered differential absorption Lidar (DIAL) measurements. The obvious advantage of light-based remote sensing modalities is their…
Among the most impactful diabetic complications are diabetic retinopathy, the leading cause of blindness among working class adults, and cardiovascular disease, the leading cause of death worldwide. This study describes the development of…
This paper proposes a method to regulate the tissue temperature during laser surgery by robotically controlling the laser focus. Laser-tissue interactions are generally considered hard to control due to the inherent inhomogeneity of…
Diabetic retinopathy is a leading cause of vision loss among adults and a major global health challenge, particularly in underserved regions. This study presents PerceptronCARE, a deep learning-based teleophthalmology application designed…
In the past few years, there are several researches on Parkinson's disease (PD) recognition using single-photon emission computed tomography (SPECT) images with deep learning (DL) approach. However, the DL model's complexity usually results…
We present a data-driven model predictive control (MPC) framework for systems with high state-space dimensionalities. This work is motivated by the need to exploit sensor data that appears in the form of images (e.g., 2D or 3D spatial…
Collisional absorption of laser light in a homogeneous, under-dense plasma is studied by a new particle-in-cell (PIC) simulation code considering one-dimensional slab-plasma geometry. Coulomb collisions between charge particles in plasma…
Adoptive Cell Transfer therapy of cancer is currently in full development and mathematical modeling is playing a critical role in this area. We study a stochastic model developed by Baar et al. in 2015 for modeling immunotherapy against…
Resin Transfer Molding (RTM), which has attracted much attention in the last years for lightweight manufacturing, represents an important challenge in terms of control technology. During the process, a resin fills the cavity where a…
Progress in automatic control of thermal processes and real-time estimation of heat penetration into live tissue has long been limited by the difficulty of obtaining high-fidelity thermodynamic models. Traditionally, in complex…
The light-based minimum-time circadian entrainment problem for mammals, Neurospora, and Drosophila is studied based on the mathematical models of their circadian gene regulation. These models contain high order nonlinear differential…
High irradiance lasers incident on metal surfaces create a complex, dynamic process through which the metal can rapidly change from highly reflective to strongly absorbing. Absolute knowledge of this process underpins important industrial…
A well-known approach to the optical measure of oxygen is based on the quenching of luminescence by molecular oxygen. The main challenge for this measuring method is the development of an accurate mathematical model. Typically, this is…
Model predictive control (MPC) provides a useful means for controlling systems with constraints, but suffers from the computational burden of repeatedly solving an optimization problem in real time. Offline (explicit) solutions for MPC…
Retinal vascular diseases affect the well-being of human body and sometimes provide vital signs of otherwise undetected bodily damage. Recently, deep learning techniques have been successfully applied for detection of diabetic retinopathy…
The suppression of high-$p_\perp$ particles is one of the main signatures of parton energy loss during its passing through the QGP medium, and is reasonably reproduced by different theoretical models. However, a decisive test of the…
Heat-based cancer treatment, so-called hyperthermia, can be used to destroy tumour cells directly or to make them more susceptible to chemotherapy or radiation therapy. To apply heat locally, iron oxide nanoparticles are injected into the…
Mathematical modelling of the microcirculatory hemodynamics in the retina is an essential tool for understanding various diseases of the retina, yet remains challenging due to the multiscale nature of the retinal vasculature and its…
Electropermeabilization is a clinical technique in cancer treatment to locally stimulate the cell metabolism. It is based on electrical fields that change the properties of the cell membrane. With that, cancer treatment can reach the cell…
Heat transfer in the human eyeball, a complex organ, is significantly influenced by various pathophysiological and external parameters. Particularly, heat transfer critically affects fluid behavior within the eye and ocular drug delivery…