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Crossover designs are widely applied in medicine, agriculture, and other biological sciences, yet their analysis remains challenging due to longitudinal observations within each unit and the presence of carry-over effects. Despite their…

统计计算 · 统计学 2025-12-18 N. A. Cruz , O. O. Melo , C. A. Martinez , R. Alberich

Bayesian optimization (BO) is a common framework for optimizing black-box functions, yet most existing methods assume static query costs and rely on myopic acquisition strategies. We introduce LookaHES, a nonmyopic BO framework designed for…

Ground truth labels/outcomes are critical for advancing scientific and engineering applications, e.g., evaluating the treatment effect of an intervention or performance of a predictive model. Since randomly sampling inputs for labeling can…

机器学习 · 计算机科学 2025-02-11 Daksh Mittal , Yuanzhe Ma , Shalmali Joshi , Hongseok Namkoong

Academic Clinical Trial Units frequently face fragmented statistical workflows, leading to duplicated effort, limited collaboration, and inconsistent analytical practices. To address these challenges within an oncology Clinical Trial Unit,…

To improve the quality of programs we provide an approach to guidance in the process of program development. At the higher level the various activities and their dependencies to structure the process are identified. At the lower level,…

软件工程 · 计算机科学 2024-11-21 Harrie Passier , Lex Bijlsma , Ruurd Kuiper , Kees Huizing

Autonomous agents for Graphical User Interfaces (GUIs) face significant challenges in specialized domains such as scientific computing, where both long-horizon planning and precise execution are required. Existing approaches suffer from a…

计算机视觉与模式识别 · 计算机科学 2025-08-28 Zeyi Sun , Yuhang Cao , Jianze Liang , Qiushi Sun , Ziyu Liu , Zhixiong Zhang , Yuhang Zang , Xiaoyi Dong , Kai Chen , Dahua Lin , Jiaqi Wang

A comprehensive pharmaceutical recommendation system was designed based on the patients and drugs features extracted from Drugs.com and Druglib.com. First, data from these databases were combined, and a dataset of patients and drug…

Current approaches rely on zero-shot evaluation due to the absence of training data; while proprietary models such as GPT-4 exhibit strong reasoning capabilities, smaller open-source models remain ineffective at complex tool use. To address…

人工智能 · 计算机科学 2026-05-05 Hyunji Min , Sangwon Jung , Junyoung Sung , Dosung Lee , Leekyeung Han , Paul Hongsuck Seo

Progress towards quantum utility in chemistry requires not only algorithmic advances, but also the identification of chemically meaningful problems whose electronic structure fundamentally challenges classical methods. Here, we introduce a…

化学物理 · 物理学 2026-01-19 Srivathsan Poyyapakkam Sundar , Vibin Abraham , Bo Peng , Ayush Asthana

Generative AI technologies promise to transform the product development lifecycle. This study evaluates the efficiency gains, areas for improvement, and emerging challenges of using GitHub Copilot, an AI-powered coding assistant. We…

软件工程 · 计算机科学 2024-06-27 Ruchika Pandey , Prabhat Singh , Raymond Wei , Shaila Shankar

The rise of powerful multimodal LLMs has enhanced the viability of building web agents which can, with increasing levels of autonomy, assist users to retrieve information and complete tasks on various human-computer interfaces. It is hence…

信息检索 · 计算机科学 2024-09-26 Maria Wang , Srinivas Sunkara , Gilles Baechler , Jason Lin , Yun Zhu , Fedir Zubach , Lei Shu , Jindong Chen

In several applied fields, multimodality assessment is a crucial task as a previous exploratory tool or for determining the suitability of certain distributions. The goal of this paper is to present the utilities of the R package multimode,…

统计计算 · 统计学 2022-11-21 Jose Ameijeiras-Alonso , Rosa M. Crujeiras , Alberto Rodríguez-Casal

Quantum computing can enable a variety of breakthroughs in research and industry in the future. Although some quantum algorithms already exist that show a theoretical speedup compared to the best known classical algorithms, the…

Quantum resource analysis is crucial for designing quantum circuits as well as assessing the viability of arbitrary (error-corrected) quantum computations. To this end, we introduce QUANTIFY, which is an open-source framework for the…

量子物理 · 物理学 2020-07-22 Oumarou Oumarou , Alexandru Paler , Robert Basmadjian

We consider applying multi-armed bandits to model-assisted designs for dose-finding clinical trials. Multi-armed bandits are very simple and powerful methods to determine actions to maximize a reward in a limited number of trials. Among the…

统计方法学 · 统计学 2022-01-17 Masahiro Kojima

Online shopping gives customers boundless options to choose from, backed by extensive product details and customer reviews, all from the comfort of home; yet, no amount of detailed, online information can outweigh the instant gratification…

人机交互 · 计算机科学 2022-07-18 Bingjie Xu , Shunan Guo , Eunyee Koh , Jane Hoffswell , Ryan Rossi , Fan Du

Bayesian optimization is a sequential decision making framework for optimizing expensive-to-evaluate black-box functions. Computing a full lookahead policy amounts to solving a highly intractable stochastic dynamic program. Myopic…

机器学习 · 计算机科学 2020-06-30 Shali Jiang , Daniel R. Jiang , Maximilian Balandat , Brian Karrer , Jacob R. Gardner , Roman Garnett

Background: Clinical predictive tools quantify contributions of relevant patient characteristics to derive likelihood of diseases or predict clinical outcomes. When selecting a predictive tool, for implementation at clinical practice or for…

计算机与社会 · 计算机科学 2019-07-09 Mohamed Khalifa , Farah Magrabi , Blanca Gallego

Mobile systems are embracing heterogeneous architectures by getting more types of cores and more specialized cores, which allows applications to be faster and more efficient. We aim at exploiting the hardware heterogeneity from the browser…

其他计算机科学 · 计算机科学 2012-12-21 Zhen Wang , Felix Xiaozhu Lin , Lin Zhong , Mansoor Chishtie

We propose a flexible, co-creative framework bringing together multiple machine learning techniques to assist human users to efficiently produce effective creative designs. We demonstrate its potential with a perfume bottle design case…

人机交互 · 计算机科学 2020-01-27 Brian Quanz , Wei Sun , Ajay Deshpande , Dhruv Shah , Jae-eun Park