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Relative survival methodology deals with a competing risks survival model where the cause of death is unknown. This lack of information occurs regularly in population-based cancer studies. Non-parametric estimation of the net survival is…

统计理论 · 数学 2025-02-14 Oskar Laverny , Nathalie Grafféo , Roch Giorgi

A survival dataset describes a set of instances (e.g. patients) and provides, for each, either the time until an event (e.g. death), or the censoring time (e.g. when lost to follow-up - which is a lower bound on the time until the event).…

机器学习 · 计算机科学 2023-06-22 Ali Hossein Gharari Foomani , Michael Cooper , Russell Greiner , Rahul G. Krishnan

Cardiovascular diseases are major causes of mortality globally. They often co-occur and are interrelated, leading to partial-order relationships among their onset times. However, these onset times are subject to informative censoring due to…

统计方法学 · 统计学 2026-04-07 Tonghui Yu , Liming Xiang

The study of survival data often requires taking proper care of the censoring mechanism that prohibits complete observation of the data. Under right censoring, only the first occurring event is observed: either the event of interest, or a…

统计理论 · 数学 2025-03-25 Myrthe D'Haen , Ingrid Van Keilegom , Anneleen Verhasselt

One of the most common ways researchers compare survival outcomes across treatments when confounding is present is using Cox regression. This model is limited by its underlying assumption of proportional hazards; in some cases, substantial…

应用统计 · 统计学 2021-02-02 Elizabeth A. Handorf , Marc Smaldone , Sujana Movva , Nandita Mitra

Estimating the cure fraction in a diseased population, especially in the presence of competing mortality causes, is crucial for both patients and clinicians. It offers a valuable measure for monitoring and interpreting trends in disease…

统计方法学 · 统计学 2025-04-08 Fabrizio Di Mari , Roberto Rocci , Silvia Rossi , Giovanna Tagliabue , Roberta De Angelis

In observational studies, the observed association between an exposure and outcome of interest may be distorted by unobserved confounding. Causal sensitivity analysis can be used to assess the robustness of observed associations to…

统计方法学 · 统计学 2025-11-04 Rui Hu , Ted Westling

Although the independent censoring assumption is commonly used in survival analysis, it can be violated when the censoring time is related to the survival time, which often happens in many practical applications. To address this issue, we…

统计方法学 · 统计学 2024-08-28 Huazhen Yu , Lixin Zhang

In this article, we develop nonparametric inference methods for comparing survival data across two samples, which are beneficial for clinical trials of novel cancer therapies where long-term survival is a critical outcome. These therapies,…

统计方法学 · 统计学 2024-09-05 Yi-Cheng Tai , Weijing Wang , Martin T. Wells

Breast cancer remains a significant global health challenge, with prognosis and treatment decisions largely dependent on clinical characteristics. Accurate prediction of patient outcomes is crucial for personalized treatment strategies.…

Variable selection is an important problem in statistics and machine learning. Copula Entropy (CE) is a mathematical concept for measuring statistical independence and has been applied to variable selection recently. In this paper we…

统计方法学 · 统计学 2022-09-07 Jian Ma

Survival outcomes are common in comparative effectiveness studies and require unique handling because they are usually incompletely observed due to right-censoring. A ``once for all'' approach for causal inference with survival outcomes…

统计方法学 · 统计学 2021-12-21 Shuxi Zeng , Fan Li , Liangyuan Hu , Fan Li

Censoring is the central problem in survival analysis where either the time-to-event (for instance, death), or the time-tocensoring (such as loss of follow-up) is observed for each sample. The majority of existing machine learning-based…

机器学习 · 统计学 2024-07-22 Weijia Zhang , Chun Kai Ling , Xuanhui Zhang

In cancer epidemiology using population-based data, regression models for the excess mortality hazard is a useful method to estimate cancer survival and to describe the association between prognosis factors and excess mortality. This method…

统计方法学 · 统计学 2019-04-19 Francisco J. Rubio , Bernard Rachet , Roch Giorgi , Camille Maringe , Aurelien Belot

Conventional survival metrics, such as Harrell's concordance index (CI) and the Brier Score, rely on the independent censoring assumption for valid inference with right-censored data. However, in the presence of so-called dependent…

机器学习 · 统计学 2025-05-20 Christian Marius Lillelund , Shi-ang Qi , Russell Greiner

In survival analysis, subjects often face competing risks; for example, individuals with cancer may also suffer from heart disease or other illnesses, which can jointly influence the prognosis of risks and censoring. Traditional survival…

机器学习 · 统计学 2025-03-12 Xin Liu , Weijia Zhang , Min-Ling Zhang

An accurate model of a patient's individual survival distribution can help determine the appropriate treatment for terminal patients. Unfortunately, risk scores (e.g., from Cox Proportional Hazard models) do not provide survival…

机器学习 · 计算机科学 2020-07-08 Humza Haider , Bret Hoehn , Sarah Davis , Russell Greiner

Multi-state models provide an extension of the usual survival/event-history analysis setting. In the medical domain, multi-state models give the possibility of further investigating intermediate events such as relapse and remission. In this…

统计方法学 · 统计学 2021-06-24 D. Manevski , H. Putter , M. Pohar Perme , E. F. Bonneville , J. Schetelig , L. C. de Wreede

Probabilistic survival analysis models seek to estimate the distribution of the future occurrence (time) of an event given a set of covariates. In recent years, these models have preferred nonparametric specifications that avoid directly…

机器学习 · 计算机科学 2025-05-08 Deming Sheng , Ricardo Henao

The conventional nonparametric tests in survival analysis, such as the log-rank test, assess the null hypothesis that the hazards are equal at all times. However, hazards are hard to interpret causally, and other null hypotheses are more…

统计方法学 · 统计学 2019-01-29 Mats Julius Stensrud , Kjetil Røysland , Pål Christie Ryalen
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