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相关论文: Quantum harmonic free energies for biomolecules an…

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Free energy sampling methods allow studying the full dynamics of activated processes. Unfortunately, the affordable accuracy of the potential describing the energy and forces of the system is usually rather low. Here we introduce a new…

化学物理 · 物理学 2019-04-04 GiovanniMaria Piccini , Michele Parrinello

Estimating vibrational entropy is a significant challenge in thermodynamics and statistical mechanics due to its reliance on quantum mechanical properties. This paper introduces a quantum algorithm designed to estimate vibrational entropy…

量子物理 · 物理学 2025-11-25 Shangjie Guo , Corneliu Buda , Nathan Wiebe

For complex molecules, nuclear degrees of freedom can act as an environment for the electronic `system' variables, allowing the theory and concepts of open quantum systems to be applied. However, when molecular system-environment…

量子物理 · 物理学 2021-01-05 Angus J. Dunnett , Alex W. Chin

Binding free energies are a key element in understanding and predicting the strength of protein--drug interactions. While classical free energy simulations yield good results for many purely organic ligands, drugs including transition metal…

We present a history-dependent Monte Carlo scheme for the efficient calculation of the free-energy of quantum systems, inspired by the Wang-Landau sampling and metadynamics method. When embedded in a path integral formulation, it is of…

统计力学 · 物理学 2009-04-08 Yanier Crespo , Alessandro Laio , Giuseppe E. Santoro , Erio Tosatti

We argue that macroscopic electrodynamics is unsuited to describe the process of radiative thermalization between a levitated nanoparticle in high vacuum and the thermal electromagnetic field. Based on physical arguments, we propose a model…

量子物理 · 物理学 2018-10-10 Adrian E. Rubio Lopez , Carlos Gonzalez-Ballestero , Oriol Romero-Isart

Analytic expressions for the energy eigenvalues and eigenfunctions of a one-dimensional harmonic crystal are obtained. The average energy and density profiles are obtained numerically as a function of temperature. A surprisingly large…

量子物理 · 物理学 2021-08-30 Phil Attard

Our understanding of the physics of biological molecules, such as proteins and DNA, is limited because the approximations we usually apply to model inert materials are not in general applicable to soft, chemically inhomogeneous systems. The…

量子物理 · 物理学 2010-07-13 Sarah Harris , Vivien M. Kendon

From the onset of fundamental statistical mechanical constructs formulated in the late 19th century, alchemical free-energy methods slowly emerged and transitioned to become operational tools of biomolecular simulation applicable to a wide…

计算物理 · 物理学 2025-10-31 Daniele Macuglia , Giovanni Ciccotti , Benoît Roux

We describe a method to compute thermodynamic quantities in the harmonic approximation for identical bosons and fermions in an external confining field. We use the canonical partition function where only energies and their degeneracies…

量子物理 · 物理学 2012-02-16 J. R. Armstrong , N. T. Zinner , D. V. Fedorov , A. S. Jensen

Ensuring a satisfactory statistical convergence of anharmonic thermodynamic properties requires sampling of many atomic configurations, however the methods to obtain those necessarily produce correlated samples, thereby reducing the…

统计力学 · 物理学 2022-06-07 Erki Metsanurk

Quantum measurements are basic operations that play a critical role in the study and application of quantum information. We study how the use of quantum, coherent, and classical thermal states of light in a circuit quantum electrodynamics…

Recent evidence suggests that quantum effects may have functional importance in biological light-harvesting systems. Along with delocalized electronic excitations, it is now suspected that quantum coherent interactions with certain…

化学物理 · 物理学 2015-10-22 Nathan Killoran , Susana F. Huelga , Martin B. Plenio

Understanding how the effectiveness of natural photosynthetic energy harvesting systems arises from the interplay between quantum coherence and environmental noise represents a significant challenge for quantum theory. Recently it has begun…

生物物理 · 物理学 2015-06-16 E. K. Irish , R. Gómez-Bombarelli , B. W. Lovett

Solving non-Hermitian quantum many-body systems on a quantum computer by minimizing the variational energy is challenging as the energy can be complex. Here, based on energy variance, we propose a variational method for solving the…

量子物理 · 物理学 2024-02-21 Xu-Dan Xie , Zheng-Yuan Xue , Dan-Bo Zhang

We develop a quantum algorithm for estimating the free energy as well as the total Gibbs state of interacting quantum Coulomb gases and molecular systems in dimensions $d \in \{2,3\}$ at finite temperature. These systems lie beyond the…

量子物理 · 物理学 2026-04-17 Simon Becker , Cambyse Rouzé , Robert Salzmann

We devise automated workflows for the calculation of Helmholtz and Gibbs free energies and their temperature and pressure dependence and provide the corresponding computational tools. We employ non-equilibrium thermodynamics for evaluating…

材料科学 · 物理学 2021-10-13 Sarath Menon , Yury Lysogorskiy , Jutta Rogal , Ralf Drautz

Focus of the chapter is on the theoretical approaches aimed to analyze thermoelectric properties at the nanoscale. We discuss several relevant theoretical approaches for different set-ups of nano-devices providing estimations of the…

介观与纳米尺度物理 · 物理学 2020-07-06 Carmine Antonio Perroni , Giuliano Benenti

We review studies of vibrational energy transfer in a molecular junction geometry, consisting of a molecule bridging two heat reservoirs, solids or large chemical compounds. This setup is of interest for applications in molecular…

介观与纳米尺度物理 · 物理学 2016-06-22 Dvira Segal , Bijay Kumar Agarwalla

Variational quantum algorithms on bosonic quantum processors are an emerging paradigm for quantum chemistry calculations, exploiting the natural alignment between molecular structure and harmonic oscillator-based hardware. We introduce the…

量子物理 · 物理学 2026-04-21 Marlon F. Jost , Sijia S. Dong