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In this paper we describe the dynamics of a vector-borne relapsing disease, such as tick-borne relapsing fever, using the methods of compartmental models. After some motivation, model description, and a brief overview of the theory of…

动力系统 · 数学 2016-08-24 Cody Palmer , Erin Landguth , Emily Stone , Tammi Johnson

Optimization of vaccine allocations among different segments of a heterogeneous population is important for enhancing the effectiveness of vaccination campaigns in reducing the burden of epidemics. Intuitively, it would seem that…

定量方法 · 定量生物学 2022-12-01 Nir Gavish , Guy Katriel

We consider the problem of estimating the reproduction number $R_t$ of an epidemic for populations where the probability of detection of cases depends on a known covariate. We argue that in such cases the normal empirical estimator can fail…

应用统计 · 统计学 2020-12-04 Guido Sanguinetti

In this paper, we derive and analyse a model for the control of arboviral diseases which takes into account an imperfect vaccine combined with some other mechanisms of control already studied in the literature. We begin by analyse the basic…

动力系统 · 数学 2016-01-12 Hamadjam Abboubakar , Jean-Claude Kamgang , Daniel Tieudjo

Optimization is at the core of control theory and appears in several areas of this field, such as optimal control, distributed control, system identification, robust control, state estimation, model predictive control and dynamic…

最优化与控制 · 数学 2019-03-14 Richard Y. Zhang , Cédric Josz , Somayeh Sojoudi

A great issue of discussion of an infectious disease is its basic reproduction number R0, which provides an estimation of the contagiousness of the disease. When R0 > 1, the disease spread will potentially lead to an outbreak, such that of…

种群与进化 · 定量生物学 2021-01-18 Dimitrios G. Patsatzis

Compartmental models have long served as important tools in mathematical epidemiology, with their usefulness highlighted by the recent COVID-19 pandemic. However, most of the classical models fail to account for certain features of this…

动力系统 · 数学 2023-08-21 Monique Chyba , Taylor Klotz , Yuriy Mileyko , Corey Shanbrom

Infectious disease transmission in human populations has a complex two-way interaction with changes in host behaviour. It is increasingly recognised that incorporating adaptive behavioural change into epidemic models is important for…

种群与进化 · 定量生物学 2026-04-14 Michael J. Plank , Matt Ryan , Lloyd Chapman , Roslyn I. Hickson , Thomas House , Emma McBryde , James M. McCaw

The basic reproduction ratio is a crucial threshold parameter in infectious disease models. In nonlocal dispersal systems, its variational characterization is challenging due to the possible absence of a principal eigenvalue caused by…

偏微分方程分析 · 数学 2026-05-27 Xiandong Lin , Jiazhuo Cheng , Qiru Wang

Many studies have proposed a relationship between COVID-19 transmissibility and ambient pollution levels. However, a major limitation in establishing such associations is to adequately account for complex disease dynamics, influenced by…

We show that the basic reproduction number of an SIS patch model with standard incidence is either strictly decreasing and strictly convex with respect to the diffusion coefficient of infected subpopulation if the patch reproduction numbers…

种群与进化 · 定量生物学 2020-01-03 Daozhou Gao , Chao-Ping Dong

Recent research indicates that many convex optimization problems with random constraints exhibit a phase transition as the number of constraints increases. For example, this phenomenon emerges in the $\ell_1$ minimization method for…

信息论 · 计算机科学 2014-04-29 Dennis Amelunxen , Martin Lotz , Michael B. McCoy , Joel A. Tropp

There are few adapted SIR models in the literature that combine vaccination and logistic growth. In this article, we study bifurcations of a SIR model where the class of Susceptible individuals grows logistically and has been subject to…

动力系统 · 数学 2023-04-26 João P. S. Maurício de Carvalho , Alexandre A. Rodrigues

The time-dependent reproduction number Rt can be used to track pathogen transmission and to assess the efficacy of interventions. This quantity can be estimated by fitting renewal equation models to time series of infectious disease case…

种群与进化 · 定量生物学 2025-01-30 Ioana Bouros , Robin Thompson , David Gavaghan , Ben Lambert

This present results lay the foundations for the study of the optimal allocation of vaccine in the simple epidemiological SIS model where one consider a very general heterogeneous population. In the present setting each individual has a…

种群与进化 · 定量生物学 2025-04-02 Jean-François Delmas , Dylan Dronnier , Pierre-André Zitt

Predictive contagion models are ubiquitous in epidemiology, social sciences, engineering, and management. This paper formulates a prescriptive contagion analytics model where a decision-maker allocates shared resources across multiple…

最优化与控制 · 数学 2023-10-24 Alexandre Jacquillat , Michael Lingzhi Li , Martin Ramé , Kai Wang

A wide range of infectious diseases are both vertically and horizontally transmitted. Such diseases are spatially transmitted via multiple species in heterogeneous environments, typically described by complex meta-population models. The…

种群与进化 · 定量生物学 2013-03-05 Ling Xue , Caterina Scoglio

We define data analyses to monitor a change in R, the average number of secondary cases caused by a typical infected individual. The input dataset consists of incident cases partitioned into outbreaks, each initiated from a single index…

种群与进化 · 定量生物学 2016-04-27 Pavel Polyakov , Romulus Breban

Prior knowledge on properties of a target model often come as discrete or combinatorial descriptions. This work provides a unified computational framework for defining norms that promote such structures. More specifically, we develop…

机器学习 · 统计学 2019-04-11 Amin Jalali , Adel Javanmard , Maryam Fazel

Recently, there has been an increasing interest in designing distributed convex optimization algorithms under the setting where the data matrix is partitioned on features. Algorithms under this setting sometimes have many advantages over…

机器学习 · 计算机科学 2016-12-05 Zihao Chen , Luo Luo , Zhihua Zhang