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In this study, we address three important challenges related to disease transmissions such as the COVID-19 pandemic, namely, (a) providing an early warning to likely exposed individuals, (b) identifying individuals who are asymptomatic, and…

种群与进化 · 定量生物学 2021-09-13 Shashanka Ubaru , Lior Horesh , Guy Cohen

The rapid spread of the Coronavirus SARS-2 is a major challenge that led almost all governments worldwide to take drastic measures to respond to the tragedy. Chief among those measures is the massive lockdown of entire countries and cities,…

Simulation of complex dynamical systems arising in many applications is computationally challenging due to their size and complexity. Model order reduction, machine learning, and other types of surrogate modeling techniques offer cheaper…

数值分析 · 数学 2026-02-11 Steven Roberts , Andrey A Popov , Arash Sarshar , Adrian Sandu

In this work we explore surrogate models to optimize plasma enhanced atomic layer deposition (PEALD) in high aspect ratio features. In plasma-based processes such as PEALD and atomic layer etching, surface recombination can dominate the…

材料科学 · 物理学 2025-06-12 Angel Yanguas-Gil , Jeffrey W. Elam

As the COVID19 spreads across the world, prevention measures are becoming the essential weapons to combat the pandemic in the period of crisis. The lockdown measure is the most controversial one as it imposes an overwhelming impact on our…

物理与社会 · 物理学 2021-02-12 Yuting Fu , Haitao Xiang , Hanqing Jin , Ning Wang

Modeling the spatiotemporal nature of the spread of infectious diseases can provide useful intuition in understanding the time-varying aspect of the disease spread and the underlying complex spatial dependency observed in people's mobility…

Epidemic risk assessment poses inherent challenges, with traditional approaches often failing to balance health outcomes and economic constraints. This paper presents a data-driven decision support tool that models epidemiological dynamics…

应用统计 · 统计学 2025-11-24 Chang Zhai , Ping Chen , Zhuo Jin , David Pitt

Analysing and understanding the transmission and evolution of the COVID-19 pandemic is mandatory to be able to design the best social and medical policies, foresee their outcomes and deal with all the subsequent socio-economic effects. We…

种群与进化 · 定量生物学 2025-07-28 Radu D. Stochiţoiu , Marian Petrica , Traian Rebedea , Ionel Popescu , Marius Leordeanu

Recent advances in healthcare technologies have led to the availability of large amounts of biological samples across several techniques and applications. In particular, in the last few years, Raman spectroscopy analysis of biological…

定量方法 · 定量生物学 2025-06-24 Marco Piazza , Andrea Spinelli , Francesca Maggioni , Marzia Bedoni , Enza Messina

Multidisciplinary design optimization methods aim at adapting numerical optimization techniques to the design of engineering systems involving multiple disciplines. In this context, a large number of mixed continuous, integer and…

The transition of the power grid requires new technologies and methodologies, which can only be developed and tested in simulations. Especially larger simulation setups with many levels of detail can become quite slow. Therefore, the number…

信号处理 · 电气工程与系统科学 2020-06-23 Stephan Balduin , Tom Westermann , Erika Puiutta

Data assimilation is used to optimally fit a classical epidemiology model to the Johns Hopkins data of the Covid-19 pandemic. The optimisation is based on the confirmed cases and confirmed deaths. This is the only data available with…

种群与进化 · 定量生物学 2020-03-31 Jörn Lothar Sesterhenn

Agent-based models have proven to be useful tools in supporting decision-making processes in different application domains. The advent of modern computers and supercomputers has enabled these bottom-up approaches to realistically model…

The increasing use of stochastic models for describing complex phenomena warrants surrogate models that capture the reference model characteristics at a fraction of the computational cost, foregoing potentially expensive Monte Carlo…

机器学习 · 计算机科学 2024-06-10 Neil Kichler , Sher Afghan , Uwe Naumann

This work focuses on optimal controls of a class of stochastic SIS epidemic models under regime switching. By assuming that a decision maker can either influence the infectivity period or isolate infected individuals, our aim is to minimize…

最优化与控制 · 数学 2021-01-12 Ky Tran , George Yin

Background: Recent work showed that the temporal growth of the novel coronavirus disease (COVID-19) follows a sub-exponential power-law scaling whenever effective control interventions are in place. Taking this into consideration, we…

种群与进化 · 定量生物学 2021-11-24 S. Triambak , D. P. Mahapatra , N. Mallick , R. Sahoo

The topology optimization of artificial neural networks can be particularly difficult if the fitness evaluations require expensive experiments or simulations. For that reason, the optimization methods may need to be supported by surrogate…

神经与进化计算 · 计算机科学 2018-07-23 Jörg Stork , Martin Zaefferer , Thomas Bartz-Beielstein

The paper proposes and investigates an approach for surrogate-assisted performance prediction of data-driven knowledge discovery algorithms. The approach is based on the identification of surrogate models for prediction of the target…

机器学习 · 计算机科学 2022-01-25 Anastasia A. Funkner , Aleksey N. Yakovlev , Sergey V. Kovalchuk

During 2020, the infection rate of COVID-19 has been investigated by many scholars from different research fields. In this context, reliable and interpretable forecasts of disease incidents are a vital tool for policymakers to manage…

机器学习 · 计算机科学 2021-01-05 Cornelius Fritz , Emilio Dorigatti , David Rügamer

The rapidly increasing prevalence of debilitating breathing disorders, such as chronic obstructive pulmonary disease (COPD), calls for a meaningful integration of artificial intelligence (AI) into healthcare. While this promises improved…

医学物理 · 物理学 2022-10-07 Harry J. Davies , Ghena Hammour , Hongjian Xiao , Danilo P. Mandic