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Epidemiological models with constant parameters may not capture satisfactory infection patterns in the presence of pharmaceutical and non-pharmaceutical mitigation measures during a pandemic, since infectiousness is a function of time. In…

种群与进化 · 定量生物学 2022-05-16 K. D. Olumoyin , A. Q. M. Khaliq , K. M. Furati

The need to forecast COVID-19 related variables continues to be pressing as the epidemic unfolds. Different efforts have been made, with compartmental models in epidemiology and statistical models such as AutoRegressive Integrated Moving…

应用统计 · 统计学 2020-10-07 Bahman Rostami-Tabar , Juan F. Rendon-Sanchez

This Overview, Design Concepts, and Details (ODD) Protocol is an ODD extension to an agent-based model (ABM) framework built for the North Carolina Modeling Infectious Diseases Program (NC MInD). The model, NC MInD ABM, can be used as a…

We study how international flights can facilitate the spread of an epidemic to a worldwide scale. We combine an infrastructure network of flight connections with a population density dataset to derive the mobility network, and then we…

物理与社会 · 物理学 2021-07-26 Hugo Dolan , Riccardo Rastelli

Studying the dynamics of COVID-19 is of paramount importance to understanding the efficiency of restrictive measures and develop strategies to defend against upcoming contagion waves. In this work, we study the spread of COVID-19 using a…

Parametric reduced-order modelling often serves as a surrogate method for hemodynamics simulations to improve the computational efficiency in many-query scenarios or to perform real-time simulations. However, the snapshots of the method…

计算工程、金融与科学 · 计算机科学 2023-10-24 Dongwei Ye , Valeria Krzhizhanovskaya , Alfons G. Hoekstra

We present "interoperability" as a guiding framework for statistical modelling to assist policy makers asking multiple questions using diverse datasets in the face of an evolving pandemic response. Interoperability provides an important set…

Mathematical models are widely recognized as an important tool for analyzing and understanding the dynamics of infectious disease outbreaks, predict their future trends, and evaluate public health intervention measures for disease control…

信号处理 · 电气工程与系统科学 2021-06-16 Yukun Tan , Durward Cator , Martial Ndeffo-Mbah , Ulisses Braga-Neto

Surrogate-assisted search-based testing (SA-SBT) aims to reduce the computational time for testing compute-intensive systems. Surrogates enhance testing techniques by improving test case generation focusing the testing budget on the most…

软件工程 · 计算机科学 2023-05-02 Shiva Nejati , Lev Sorokin , Damir Safin , Federico Formica , Mohammad Mahdi Mahboob , Claudio Menghi

Adaptive designs are increasingly used in clinical trials and online experiments to improve participant outcomes by dynamically updating treatment allocation as data accumulate. In practice, experimenters often consider multiple candidate…

统计方法学 · 统计学 2026-04-08 Wenxin Zhang , Aaron Hudson , Maya Petersen , Mark van der Laan

In this paper, a mathematical model is proposed to analyze the dynamic behavior of COVID-19. Based on inter-city networked coupling effects, a fractional-order SEIHDR system with the real-data from 23 January to 18 March, 2020 of COVID-19…

物理与社会 · 物理学 2020-05-01 Zhenzhen Lu , Yongguang Yu , YangQuan Chen , Guojian Ren , Conghui Xu , Shuhui Wang , Zhe Yin

The onset of the COVID-19 pandemic drove a widespread, often uncoordinated effort by research groups to develop mathematical models of SARS-CoV-2 to study its spread and inform control efforts. The urgent demand for insight at the outset of…

Parameter identification for marine ecosystem models is important for the assessment and validation of marine ecosystem models against observational data. The surrogate-based optimization (SBO) is a computationally efficient method to…

大气与海洋物理 · 物理学 2021-12-01 Markus Pfeil , Thomas Slawig

We introduce a Bayesian sequential data assimilation method for COVID-19 forecasting. It is assumed that suitable transmission, epidemic and observation models are available and previously validated and the transmission and epidemic models…

We demonstrate the ability of statistical data assimilation to identify the measurements required for accurate state and parameter estimation in an epidemiological model for the novel coronavirus disease COVID-19. Our context is an effort…

种群与进化 · 定量生物学 2020-08-04 Eve Armstrong , Manuela Runge , Jaline Gerardin

This paper is concerned with the well-posedness and optimal control problem of a reaction-diffusion system for an epidemic Susceptible-Infected-Recovered-Susceptible (SIRS) mathematical model in which the dynamics develops in a spatially…

最优化与控制 · 数学 2023-04-24 Pierluigi Colli , Gianni Gilardi , Gabriela Marinoschi , Elisabetta Rocca

We propose a new approach for building recommender systems by adapting surrogate-assisted interactive genetic algorithms. A pool of user-evaluated items is used to construct an approximative model which serves as a surrogate fitness…

神经与进化计算 · 计算机科学 2019-08-09 Thomas Gabor , Philipp Altmann

Viral outbreaks, such as the current COVID-19 pandemic, are commonly described by compartmental models by means of ordinary differential equation (ODE) systems. The parameter values of these ODE models are typically unknown and need to be…

种群与进化 · 定量生物学 2021-11-19 Jacques Hermes , Marcus Rosenblatt , Christian Tönsing , Jens Timmer

The SARS-CoV-2 infectious outbreak has rapidly spread across the globe and precipitated varying policies to effectuate physical distancing to ameliorate its impact. In this study, we propose a new hybrid machine learning model, SIRNet, for…

Severe acute respiratory disease SARS-CoV-2 has had a found impact on public health systems and healthcare emergency response especially with respect to making decisions on the most effective measures to be taken at any given time. As…

机器学习 · 计算机科学 2023-09-19 Charithea Stylianides , Kleanthis Malialis , Panayiotis Kolios