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Mitosis nuclei count is one of the important indicators for the pathological diagnosis of breast cancer. The manual annotation needs experienced pathologists, which is very time-consuming and inefficient. With the development of deep…

计算机视觉与模式识别 · 计算机科学 2022-12-29 Huadeng Wang , Zhipeng Liu , Rushi Lan , Zhenbing Liu , Xiaonan Luo , Xipeng Pan , Bingbing Li

Each woman living in the United States has about 1 in 8 chance of developing invasive breast cancer. The mitotic cell count is one of the most common tests to assess the aggressiveness or grade of breast cancer. In this prognosis,…

计算机视觉与模式识别 · 计算机科学 2022-02-18 Robin Elizabeth Yancey

Counting of mitotic figures is a fundamental step in grading and prognostication of several cancers. However, manual mitosis counting is tedious and time-consuming. In addition, variation in the appearance of mitotic figures causes a high…

计算机视觉与模式识别 · 计算机科学 2023-09-26 Mostafa Jahanifar , Adam Shephard , Neda Zamanitajeddin , Simon Graham , Shan E Ahmed Raza , Fayyaz Minhas , Nasir Rajpoot

Automated detection of mitotic figures in histopathology images has seen vast improvements, thanks to modern deep learning-based pipelines. Application of these methods, however, is in practice limited by strong variability of images…

Mitotic figure count is an important marker of tumor proliferation and has been shown to be associated with patients' prognosis. Deep learning based mitotic figure detection methods have been utilized to automatically locate the cell in…

计算机视觉与模式识别 · 计算机科学 2021-09-01 Jingtang Liang , Cheng Wang , Yujie Cheng , Zheng Wang , Fang Wang , Liyu Huang , Zhibin Yu , Yubo Wang

The difficulty of detecting mitosis and its similarity to non-mitosis objects has remained a challenge in computational pathology. The lack of publicly available data has added more complexity. Deep learning algorithms have shown potentials…

图像与视频处理 · 电气工程与系统科学 2021-10-25 Seyed H. Mirjahanmardi , Samir Mitha , Salar Razavi , Susan Done , April Khademi

Mitotic counting is a vital prognostic marker of tumor proliferation in breast cancer. Deep learning-based mitotic detection is on par with pathologists, but it requires large labeled data for training. We propose a deep classification…

计算机视觉与模式识别 · 计算机科学 2020-07-03 Pushpak Pati , Antonio Foncubierta-Rodriguez , Orcun Goksel , Maria Gabrani

This is the submission for mitosis detection in the context of the MIDOG 2021 challenge. It is based on the two-stage objection model Faster RCNN as well as DenseNet as a backbone for the neural network architecture. It achieves a F1-score…

计算机视觉与模式识别 · 计算机科学 2021-09-03 Michel Halmes , Hippolyte Heuberger , Sylvain Berlemont

Mitotic figure (MF) detection in histopathology images is challenging due to large variations in slide scanners, staining protocols, tissue types, and the presence of artifacts. This paper presents a collection of training techniques - a…

计算机视觉与模式识别 · 计算机科学 2025-08-28 Christian Marzahl , Brian Napora

Accurate detection of mitosis plays a critical role in breast cancer histopathology. Manual detection and counting of mitosis is tedious and subject to considerable inter- and intra-reader variations. Multispectral imaging is a recent…

计算机视觉与模式识别 · 计算机科学 2013-04-16 H. Irshad , A. Gouaillard , L. Roux , D. Racoceanu

Mitotic figure detection is a challenging task in digital pathology that has a direct impact on therapeutic decisions. While automated methods often achieve acceptable results under laboratory conditions, they frequently fail in the…

图像与视频处理 · 电气工程与系统科学 2022-01-21 Jakob Dexl , Michaela Benz , Volker Bruns , Petr Kuritcyn , Thomas Wittenberg

Mitotic counts are one of the key indicators of breast cancer prognosis. However, accurate mitotic cell counting is still a difficult problem and is labourious. Automated methods have been proposed for this task, but are usually dependent…

计算机视觉与模式识别 · 计算机科学 2021-09-28 Salar Razavi , Fariba Dambandkhameneh , Dimitri Androutsos , Susan Done , April Khademi

The detection of mitotic figures from different scanners/sites remains an important topic of research, owing to its potential in assisting clinicians with tumour grading. The MItosis DOmain Generalization (MIDOG) challenge aims to test the…

计算机视觉与模式识别 · 计算机科学 2021-09-30 Mostafa Jahanifar , Adam Shephard , Neda Zamani Tajeddin , R. M. Saad Bashir , Mohsin Bilal , Syed Ali Khurram , Fayyaz Minhas , Nasir Rajpoot

Domain variability is a common bottle neck in developing generalisable algorithms for various medical applications. Motivated by the observation that the domain variability of the medical images is to some extent compact, we propose to…

图像与视频处理 · 电气工程与系统科学 2021-10-01 Mustaffa Hussain , Ritesh Gangnani , Sasidhar Kadiyala

Breast cancer is the most commonly diagnosed cancer worldwide, with over two million new cases each year. During diagnostic tumour grading, pathologists manually count the number of dividing cells (mitotic figures) in biopsy or tumour…

图像与视频处理 · 电气工程与系统科学 2022-01-19 Jack Breen , Kieran Zucker , Nicolas M. Orsi , Nishant Ravikumar

The density of mitotic figures within tumor tissue is known to be highly correlated with tumor proliferation and thus is an important marker in tumor grading. Recognition of mitotic figures by pathologists is known to be subject to a strong…

The effective localization of mitosis is a critical precursory task for deciding tumor prognosis and grade. Automated mitosis detection through deep learning-oriented image analysis often fails on unseen patient data due to inherent domain…

计算机视觉与模式识别 · 计算机科学 2022-09-20 Tirupati Saketh Chandr , Sahar Almahfouz Nasser , Nikhil Cherian Kurian , Amit Sethi

The account of mitotic cells is a key feature in tumor diagnosis. However, due to the variability of mitotic cell morphology, it is a highly challenging task to detect mitotic cells in tumor tissues. At the same time, although advanced deep…

计算机视觉与模式识别 · 计算机科学 2022-08-29 Chen Yang , Wang Ziyue , Fang Zijie , Bian Hao , Zhang Yongbing

The proliferative activity of breast tumors, which is routinely estimated by counting of mitotic figures in hematoxylin and eosin stained histology sections, is considered to be one of the most important prognostic markers. However, mitosis…

Counting mitotic figures is time-intensive for pathologists and leads to inter-observer variability. Artificial intelligence (AI) promises a solution by automatically detecting mitotic figures while maintaining decision consistency.…

计算机视觉与模式识别 · 计算机科学 2025-09-08 Seungho Choe , Xiaoli Qin , Abubakr Shafique , Amanda Dy , Susan Done , Dimitrios Androutsos , April Khademi
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