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A key parameter in models for the spread of infectious diseases is the basic reproduction number $R_0$, which is the expected number of secondary cases a typical infected primary case infects during its infectious period in a large mostly…

种群与进化 · 定量生物学 2017-09-05 Kristoffer Spricer , Pieter Trapman

The basic reproductive number -- $R_0$ -- is one of the most common and most commonly misapplied numbers in public health. Although often used to compare outbreaks and forecast pandemic risk, this single number belies the complexity that…

种群与进化 · 定量生物学 2020-04-15 Laurent Hébert-Dufresne , Benjamin M. Althouse , Samuel V. Scarpino , Antoine Allard

The basic reproduction number, $R_0$, is a well-known quantifier of epidemic spread. However, a class of existing methods for estimating $R_0$ from incidence data early in the epidemic can lead to an over-estimation of this quantity. In…

种群与进化 · 定量生物学 2024-03-27 Wajid Ali , Christopher E. Overton , Robert R. Wilkinson , Kieran J. Sharkey

Stochastic discrete-time SIS and SIR models of endemic diseases are introduced and analyzed. For the deterministic, mean-field model, the basic reproductive number $R_0$ determines their global dynamics. If $R_0\le 1$, then the frequency of…

种群与进化 · 定量生物学 2020-05-19 Sebastian J. Schreiber , Shuo Huang , Jifa Jiang , Hao Wang

Multiple-type branching processes that model the spread of infectious diseases are investigated. In these stochastic processes, the disease goes through multiple stages before it eventually disappears. We mostly focus on the critical…

种群与进化 · 定量生物学 2015-06-04 Tibor Antal , P. L. Krapivsky

We define and study an open stochastic SIR (Susceptible -- Infected -- Removed) model on a graph in order to describe the spread of an epidemic on a cattle trade network with epidemiological and demographic dynamics occurring over the same…

概率论 · 数学 2019-03-28 Pierre Montagnon

Early estimates of the transmission potential of emerging and re-emerging infections are increasingly used to inform public health authorities on the level of risk posed by outbreaks. Existing methods to estimate the reproduction number…

定量方法 · 定量生物学 2016-10-10 Gerardo Chowell , Cécile Viboud , Lone Simonsen , Seyed Moghadas

We consider a stochastic model of infection spread on the complete graph on $N$ vertices incorporating dynamic partnerships, which we assume to be monogamous. This can be seen as a variation on the contact process in which some form of edge…

概率论 · 数学 2016-06-23 Eric Foxall , Roderick Edwards , P. van den Driessche

Studies about epidemic modelling have been conducted since before 19th century. Both deterministic and stochastiic model were used to capture the dynamic of infection in the population. The purpose of this project is to investigate the…

种群与进化 · 定量生物学 2018-03-06 Kurnia Susvitasari

When controlling an emerging outbreak of an infectious disease it is essential to know the key epidemiological parameters, such as the basic reproduction number $R_0$ and the control effort required to prevent a large outbreak. These…

种群与进化 · 定量生物学 2016-04-18 Pieter Trapman , Frank Ball , Jean-Stéphane Dhersin , Viet Chi Tran , Jacco Wallinga , Tom Britton

The current survey paper concerns stochastic mathematical models for the spread of infectious diseases. It starts with the simplest setting of a homogeneous population in which a transmittable disease spreads during a short outbreak.…

应用统计 · 统计学 2018-01-30 Tom Britton

Consider a large uniformly mixing dynamic population, which has constant birth rate and exponentially distributed lifetimes, with mean population size $n$. A Markovian SIR (susceptible $\to$ infective $\to$ recovered) infectious disease,…

概率论 · 数学 2015-06-09 Frank Ball , Tom Britton , Pieter Trapman

Using a probability of novel encounter derived from a physical model, we augment the SIR compartmental model for disease spread. Scenarios with the same initial trajectories and identical $R_0$ values can diverge greatly depending on the…

种群与进化 · 定量生物学 2020-06-15 Peter Cotton

The dynamics of epidemic spreading is often reduced to the single control parameter $R_0$, whose value, above or below unity, determines the state of the contagion. If, however, the pathogen evolves as it spreads, $R_0$ may change over…

种群与进化 · 定量生物学 2022-11-07 Xiyun Zhang , Zhongyuan Ruan , Muhua Zheng , Jie Zhou , Stefano Boccaletti , Baruch Barzel

This paper is concerned with a nonlocal dispersal susceptible-infected-susceptible (SIS) epidemic model with Dirichlet boundary condition, where the rates of disease transmission and recovery are assumed to be spatially heterogeneous. We…

偏微分方程分析 · 数学 2016-01-21 Fei-Ying Yang , Wan-Tong Li

An important issue in theoretical epidemiology is the epidemic threshold phenomenon, which specify the conditions for an epidemic to grow or die out. In standard (mean-field-like) compartmental models the concept of the basic reproductive…

生物物理 · 物理学 2007-05-23 D. Alves , V. J. Haas , A. Caliri

The main aim of the work is to present a general class of two time scales discrete-time epidemic models. In the proposed framework the disease dynamics is considered to act on a slower time scale than a second different process that could…

动力系统 · 数学 2024-02-07 Luis Sanz-Lorenzo , Rafael Bravo de la Parra

The expected number of secondary infections arising from each index case, referred to as the reproduction or $R$ number, is a vital summary statistic for understanding and managing epidemic diseases. There are many methods for estimating…

应用统计 · 统计学 2022-02-22 Joe Meagher , Nial Friel

In this work, we review the figures used to characterize an epidemic outbreak most. Particular attention is drawn to epidemic spreading at time-varying transition rates. A time-varying SIR-like model is used to describe the epidemic…

We introduce an epidemic model with varying infectivity and general exposed and infectious periods, where the infectivity of each individual is a random function of the elapsed time since infection, those function being i.i.d. for the…

概率论 · 数学 2021-06-01 Raphael Forien , Guodong Pang , Etienne Pardoux
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