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False discovery rate (FDR) has been widely used as an error measure in large scale multiple testing problems, but most research in the area has been focused on procedures for controlling the FDR based on independent test statistics or the…

统计方法学 · 统计学 2009-09-29 Weihua Tang , Cun-Hui Zhang

Results on the false discovery rate (FDR) and the false nondiscovery rate (FNR) are developed for single-step multiple testing procedures. In addition to verifying desirable properties of FDR and FNR as measures of error rates, these…

统计理论 · 数学 2007-06-13 Sanat K. Sarkar

This paper outlines a unified framework for high dimensional variable selection for classification problems. Traditional approaches to finding interesting variables mostly utilize only partial information through moments (like mean…

统计方法学 · 统计学 2016-11-25 S. Mukhopadhyay , Emanuel Parzen , S. N. Lahiri

In a context of multiple hypothesis testing, we provide several new exact calculations related to the false discovery proportion (FDP) of step-up and step-down procedures. For step-up procedures, we show that the number of erroneous…

统计理论 · 数学 2011-06-29 Etienne Roquain , Fanny Villers

Consider the multiple testing problem of testing null hypotheses $H_1,...,H_s$. A classical approach to dealing with the multiplicity problem is to restrict attention to procedures that control the familywise error rate ($\mathit{FWER}$),…

统计理论 · 数学 2007-06-13 Joseph P. Romano , Azeem M. Shaikh

While traditional multiple testing procedures prohibit adaptive analysis choices made by users, Goeman and Solari (2011) proposed a simultaneous inference framework that allows users such flexibility while preserving high-probability bounds…

统计理论 · 数学 2021-01-05 Eugene Katsevich , Aaditya Ramdas

Multiple testing problems arising in modern scientific applications can involve simultaneously testing thousands or even millions of hypotheses, with relatively few true signals. In this paper, we consider the multiple testing problem where…

统计方法学 · 统计学 2016-06-28 Ang Li , Rina Foygel Barber

In this article, we propose a generalized weighted version of the well-known Benjamini-Hochberg (BH) procedure. The rigorous weighting scheme used by our method enables it to encode structural information from simultaneous multi-way…

统计方法学 · 统计学 2021-05-25 Shinjini Nandi , Sanat K. Sarkar

Benjamini and Hochberg (1995) proposed the false discovery rate (FDR) as an alternative to the family-wise error rate in multiple testing problems, and proposed a procedure to control the FDR. For discrete data this procedure may be highly…

统计方法学 · 统计学 2014-01-28 Ruth Heller , Hadas Gur

Recent discoveries suggest that our gut microbiome plays an important role in our health and wellbeing. However, the gut microbiome data are intricate; for example, the microbial diversity in the gut makes the data high-dimensional. While…

统计方法学 · 统计学 2021-03-02 Fang Xie , Johannes Lederer

In high-dimensional data analysis, such as financial index tracking or biomedical applications, it is crucial to select the few relevant variables while maintaining control over the false discovery rate (FDR). In these applications, strong…

投资组合管理 · 定量金融 2024-01-31 Jasin Machkour , Daniel P. Palomar , Michael Muma

Conventional multiple testing procedures often assume hypotheses for different features are exchangeable. However, in many scientific applications, additional covariate information regarding the patterns of signals and nulls are available.…

统计方法学 · 统计学 2020-06-12 Xianyang Zhang , Jun Chen

This paper proposes a reliable neural network pruning algorithm by setting up a scientific control. Existing pruning methods have developed various hypotheses to approximate the importance of filters to the network and then execute filter…

计算机视觉与模式识别 · 计算机科学 2021-01-12 Yehui Tang , Yunhe Wang , Yixing Xu , Dacheng Tao , Chunjing Xu , Chao Xu , Chang Xu

In many modern applications, large-scale sensor networks are used to perform statistical inference tasks. In this paper, we propose Bayesian methods for multiple change-point detection using a sensor network in which a fusion center (FC)…

信息论 · 计算机科学 2023-07-19 Eyal Nitzan , Topi Halme , Visa Koivunen

Identifying variants that carry substantial information on the trait of interest remains a core topic in genetic studies. In analyzing the EADB-UKBB dataset to identify genetic variants associated with Alzheimer's disease (AD), however, we…

应用统计 · 统计学 2025-12-04 Jiaqi Gu , Zhaomeng Chen , Zihuai He

Multiple hypothesis testing with false discovery rate (FDR) control is a fundamental problem in statistical inference, with broad applications in genomics, drug screening, and outlier detection. In many such settings, researchers may have…

统计方法学 · 统计学 2026-02-19 Yonghoon Lee , Meshi Bashari , Edgar Dobriban , Yaniv Romano

Differential privacy provides a rigorous framework for privacy-preserving data analysis. This paper proposes the first differentially private procedure for controlling the false discovery rate (FDR) in multiple hypothesis testing. Inspired…

统计理论 · 数学 2021-07-06 Cynthia Dwork , Weijie J. Su , Li Zhang

Feature selection prepares the AI-readiness of data by eliminating redundant features. Prior research falls into two primary categories: i) Supervised Feature Selection, which identifies the optimal feature subset based on their relevance…

机器学习 · 计算机科学 2024-03-08 Xinyuan Wang , Dongjie Wang , Wangyang Ying , Rui Xie , Haifeng Chen , Yanjie Fu

Multiple hypothesis testing often involves composite nulls, i.e., nulls that are associated with two or more distributions. In many cases, it is reasonable to assume that there is a prior distribution on the distributions despite it is…

统计理论 · 数学 2008-07-31 Zhiyi Chi

In the context of multiple hypotheses testing, the proportion $\pi_0$ of true null hypotheses in the pool of hypotheses to test often plays a crucial role, although it is generally unknown a priori. A testing procedure using an implicit or…

统计理论 · 数学 2009-02-17 Gilles Blanchard , Etienne Roquain
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