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The log-det distance between two aligned DNA sequences was introduced as a tool for statistically consistent inference of a gene tree under simple non-mixture models of sequence evolution. Here we prove that the log-det distance, coupled…

种群与进化 · 定量生物学 2018-06-14 Elizabeth S. Allman , Colby Long , John A. Rhodes

We consider the problem of estimating species trees from unrooted gene tree topologies in the presence of incomplete lineage sorting, a common phenomenon that creates gene tree heterogeneity in multilocus datasets. One popular class of…

种群与进化 · 定量生物学 2018-12-21 Sebastien Roch

We consider the problem of estimating the evolutionary history of a set of species (phylogeny or species tree) from several genes. It is known that the evolutionary history of individual genes (gene trees) might be topologically distinct…

种群与进化 · 定量生物学 2016-11-18 Gautam Dasarathy , Robert Nowak , Sebastien Roch

Species networks generalize the notion of species trees to allow for hybridization or other lateral gene transfer. Under the Network Multispecies Coalescent Model, individual gene trees arising from a network can have any topology, but…

种群与进化 · 定量生物学 2019-05-20 Elizabeth Allman , Hector Banos , John Rhodes

When hybridization or other forms of lateral gene transfer have occurred, evolutionary relationships of species are better represented by phylogenetic networks than by trees. While inference of such networks remains challenging, several…

种群与进化 · 定量生物学 2024-01-15 Elizabeth S. Allman , Hector Baños , Marina Garrote-Lopez , John A. Rhodes

Inference of species networks from genomic data under the Network Multispecies Coalescent Model is currently severely limited by heavy computational demands. It also remains unclear how complicated networks can be for consistent inference…

种群与进化 · 定量生物学 2022-05-10 Elizabeth S. Allman , Hector Baños , Jonathan D. Mitchell , John A. Rhodes

The inference of phylogenetic networks, which model complex evolutionary processes including hybridization and gene flow, remains a central challenge in evolutionary biology. Until now, statistically consistent inference methods have been…

We show that many topological features of level-1 species networks are identifiable from the distribution of the gene tree quartets under the network multi-species coalescent model. In particular, every cycle of size at least 4 and every…

种群与进化 · 定量生物学 2017-11-30 Hector Baños

The reconstruction of a species phylogeny from genomic data faces two significant hurdles: 1) the trees describing the evolution of each individual gene--i.e., the gene trees--may differ from the species phylogeny and 2) the molecular…

机器学习 · 计算机科学 2017-07-17 Gautam Dasarathy , Elchanan Mossel , Robert Nowak , Sebastien Roch

The inference of the evolutionary history of a collection of organisms is a problem of fundamental importance in evolutionary biology. The abundance of DNA sequence data arising from genome sequencing projects has led to significant…

种群与进化 · 定量生物学 2015-07-07 Julia Chifman , Laura Kubatko

We consider the reconstruction of a phylogeny from multiple genes under the multispecies coalescent. We establish a connection with the sparse signal detection problem, where one seeks to distinguish between a distribution and a mixture of…

概率论 · 数学 2017-07-24 Elchanan Mossel , Sebastien Roch

One approach to estimating a species tree from a collection of gene trees is to first estimate probabilities of clades from the gene trees, and then to construct the species tree from the estimated clade probabilities. While a greedy…

种群与进化 · 定量生物学 2012-11-14 Elizabeth S. Allman , James H. Degnan , John A. Rhodes

The behavior of ecological systems mainly relies on the interactions between the species it involves. We consider the problem of inferring the species interaction network from abundance data. To be relevant, any network inference…

应用统计 · 统计学 2019-10-29 Raphaëlle Momal , Stéphane Robin , Christophe Ambroise

A wide range of applications and research has been done with genome-scale metabolic models. In this work we describe a methodology for comparing metabolic networks constructed from genome-scale metabolic models and how to apply this…

分子网络 · 定量生物学 2026-02-06 D. Gamermann , A. Montagud , J. A. Conejero , P. F. de Córdoba , J. F. Urchieguía

Phylogenetic networks extend phylogenetic trees to model non-vertical inheritance, by which a lineage inherits material from multiple parents. The computational complexity of estimating phylogenetic networks from genome-wide data with…

种群与进化 · 定量生物学 2022-06-28 Jingcheng Xu , Cécile Ané

As researchers collect increasingly large molecular data sets to reconstruct the Tree of Life, the heterogeneity of signals in the genomes of diverse organisms poses challenges for traditional phylogenetic analysis. A class of phylogenetic…

种群与进化 · 定量生物学 2015-09-11 Liang Liu , Zhenxiang Xi , Shaoyuan Wu , Charles Davis , Scott V. Edwards

Phylogenetic networks are increasingly used in evolutionary biology to represent the history of species that have undergone reticulate events such as horizontal gene transfer, hybrid speciation and recombination. One of the most fundamental…

种群与进化 · 定量生物学 2016-10-07 Philippe Gambette , Leo van Iersel , Steven Kelk , Fabio Pardi , Celine Scornavacca

Control and characterization of networks is a paramount step for the development of many quantum technologies. Even for moderate-sized networks, this amounts to explore an extremely vast parameters space in search for the couplings defining…

量子物理 · 物理学 2024-05-30 Claudia Benedetti , Ilaria Gianani

A phylogenetic network is a graph-theoretical tool that is used by biologists to represent the evolutionary history of a collection of species. One potential way of constructing such networks is via a distance-based approach, where one is…

组合数学 · 数学 2020-06-15 Leo van Iersel , Vincent Moulton , Yukihiro Murakami

Phylogenetic networks model reticulate evolutionary histories. The last two decades have seen an increased interest in establishing mathematical results and developing computational methods for inferring and analyzing these networks. A…

种群与进化 · 定量生物学 2016-06-24 Jiafan Zhu , Yun Yu , Luay Nakhleh
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