中文
相关论文

相关论文: Covariate adjustment in randomised trials: canonic…

200 篇论文

Randomized clinical trials typically aim to estimate a marginal treatment effect. While covariate adjustment can improve precision, it may change the estimand in nonlinear models due to noncollapsibility, leading to conditional rather than…

统计方法学 · 统计学 2026-05-25 Leticia Wuethrich , Torsten Hothorn

Linear regression is a frequently used tool in statistics, however, its validity and interpretability relies on strong model assumptions. While robust estimates of the coefficients' covariance extend the validity of hypothesis tests and…

统计方法学 · 统计学 2015-04-23 Werner Brannath , Martin Scharpenberg

We consider the problem of testing for the presence of linear relationships between large sets of random variables based on a post-selection inference approach to canonical correlation analysis. The challenge is to adjust for the selection…

统计方法学 · 统计学 2020-10-20 Ian W. McKeague , Xin Zhang

Traditional methods for covariate adjustment of treatment means in designed experiments are inherently conditional on the observed covariate values. In order to develop a coherent general methodology for analysis of covariance, we propose a…

统计方法学 · 统计学 2010-01-19 James G. Booth , Walter T. Federer , Martin T. Wells , Russell D. Wolfinger

Rerandomization enforces covariate balance across treatment groups in the design stage of experiments. Despite its intuitive appeal, its theoretical justification remains unsatisfying because its benefits of improving efficiency for…

统计理论 · 数学 2025-05-05 Xin Lu , Peng Ding

Covariance regression analysis is an approach to linking the covariance of responses to a set of explanatory variables $X$, where $X$ can be a vector, matrix, or tensor. Most of the literature on this topic focuses on the "Fixed-$X$"…

统计理论 · 数学 2025-01-08 Tao Zou , Wei Lan , Runze Li , Chih-Ling Tsai

Randomized trials are considered the gold standard for making informed decisions in medicine, yet they often lack generalizability to the patient populations in clinical practice. Observational studies, on the other hand, cover a broader…

统计方法学 · 统计学 2026-04-14 Piersilvio De Bartolomeis , Javier Abad , Konstantin Donhauser , Fanny Yang

Data analysis of files that are a result of linking records from multiple sources are often affected by linkage errors. Records may be linked incorrectly, or their links may be missed. In consequence, it is essential that such errors are…

统计方法学 · 统计学 2025-10-21 Priyanjali Bukke , Martin Slawski

The Regression Discontinuity (RD) design is a widely used non-experimental method for causal inference and program evaluation. While its canonical formulation only requires a score and an outcome variable, it is common in empirical work to…

统计方法学 · 统计学 2022-08-25 Matias D. Cattaneo , Luke Keele , Rocio Titiunik

To estimate casual treatment effects, we propose a new matching approach based on the reduced covariates obtained from sufficient dimension reduction. Compared to the original covariates and the propensity score, which are commonly used for…

统计方法学 · 统计学 2017-02-03 Wei Luo , Yeying Zhu

Randomization tests and flexible treatment-effect models offer complementary strengths for analyzing data from randomized panel experiments: the former provide valid inference under the known assignment mechanism, while the latter can…

统计方法学 · 统计学 2026-05-12 Fangnan Zheng , Yao Zhang

In this paper linear canonical correlation analysis (LCCA) is generalized by applying a structured transform to the joint probability distribution of the considered pair of random vectors, i.e., a transformation of the joint probability…

统计方法学 · 统计学 2015-06-03 Koby Todros , Alfred O. Hero

Imbalances in covariates between treatment groups are frequent in observational studies and can lead to biased comparisons. Various adjustment methods can be employed to correct these biases in the context of multi-level treatments ($>$ 2).…

应用统计 · 统计学 2021-06-04 Diop S. Arona , Duchesne Thierry , Cumming Steven , Diop Awa , Talbot Denis

Reliable uncertainty estimates are an important tool for helping autonomous agents or human decision makers understand and leverage predictive models. However, existing approaches to estimating uncertainty largely ignore the possibility of…

机器学习 · 计算机科学 2020-05-22 Sangdon Park , Osbert Bastani , James Weimer , Insup Lee

In randomized clinical trials, adjusting for baseline covariates can improve credibility and efficiency for demonstrating and quantifying treatment effects. This article studies the augmented inverse propensity weighted (AIPW) estimator,…

统计方法学 · 统计学 2024-03-27 Marlena S. Bannick , Jun Shao , Jingyi Liu , Yu Du , Yanyao Yi , Ting Ye

Identifying effects of actions (treatments) on outcome variables from observational data and causal assumptions is a fundamental problem in causal inference. This identification is made difficult by the presence of confounders which can be…

统计方法学 · 统计学 2012-03-19 Ilya Shpitser , Tyler VanderWeele , James M. Robins

Randomized experiments have been the gold standard for drawing causal inference. The conventional model-based approach has been one of the most popular ways for analyzing treatment effects from randomized experiments, which is often carried…

统计方法学 · 统计学 2024-11-19 Tianyi Qu , Jiangchuan Du , Xinran Li

We consider high-dimensional generalized linear models when the covariates are contaminated by measurement error. Estimates from errors-in-variables regression models are well-known to be biased in traditional low-dimensional settings if…

统计计算 · 统计学 2020-01-06 Michael Byrd , Monnie McGee

Balancing influential covariates is crucial for valid treatment comparisons in clinical studies. While covariate-adaptive randomization is commonly used to achieve balance, its performance can be inadequate when the number of baseline…

统计方法学 · 统计学 2024-12-30 Ziqing Guo , Yang Liu , Lucy Xia

In randomized controlled trials without interference, regression adjustment is widely used to enhance the efficiency of treatment effect estimation. This paper extends this efficiency principle to settings with network interference, where a…

统计方法学 · 统计学 2025-02-18 Xinyuan Fan , Chenlei Leng , Weichi Wu