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The identification of patient subgroups with comparable event-risk dynamics plays a key role in supporting informed decision-making in clinical research. In such settings, it is important to account for the inherent dependence that arises…

统计计算 · 统计学 2026-01-13 Alessandra Ragni , Lara Cavinato , Francesca Ieva

Precision oncology aims to prescribe the optimal cancer treatment to the right patients, maximizing therapeutic benefits. However, identifying patient subgroups that may benefit more from experimental cancer treatments based on randomized…

统计方法学 · 统计学 2026-01-06 Xingyu Li , Qing Liu , Tony Jiang , Hong Amy Xia , Peng Wei , Brian P. Hobbs

Problem definition: Mining for heterogeneous responses to an intervention is a crucial step for data-driven operations, for instance to personalize treatment or pricing. We investigate how to estimate price sensitivity from…

统计方法学 · 统计学 2025-01-08 Jean Pauphilet

With the timely formation of personalized intervention plans based on high-dimensional heterogeneous time series information becoming an important challenge in the medical field today, electronic medical records, wearables, and other…

人工智能 · 计算机科学 2025-04-29 Dingxin Lu , Shurui Wu , Xinyi Huang

With an ever growing number of heterogeneous applicational services running on equally heterogeneous computational systems, the problem of resource management becomes more essential. Although current solutions consider some network and time…

分布式、并行与集群计算 · 计算机科学 2025-08-05 Rui Eduardo Lopes , Duarte Raposo , Pedro V. Teixeira , Susana Sargento

Patient length of stay (LoS) is a critical metric for evaluating the efficacy of hospital management. The primary objectives encompass to improve efficiency and reduce costs while enhancing patient outcomes and hospital capacity within the…

机器学习 · 计算机科学 2025-01-31 Tasfia Noor Chowdhury , Sanjida Afrin Mou , Kazi Naimur Rahman

Problem: How can we design patient cost prediction models that effectively address the challenges of heterogeneity in administrative claims (AC) data to ensure accurate, fair, and generalizable predictions, especially for high-need (HN)…

机器学习 · 计算机科学 2025-02-19 Mohammad Amin Morid , Olivia R. Liu Sheng

We develop a personalized real time risk scoring algorithm that provides timely and granular assessments for the clinical acuity of ward patients based on their (temporal) lab tests and vital signs. Heterogeneity of the patients population…

机器学习 · 计算机科学 2016-05-04 Ahmed M. Alaa , Jinsung Yoon , Scott Hu , Mihaela van der Schaar

Readmission prediction is a critical but challenging clinical task, as the inherent relationship between high-dimensional covariates and readmission is complex and heterogeneous. Despite this complexity, models should be interpretable to…

统计方法学 · 统计学 2025-07-10 Wei Wang , Angela Bailey , Christopher Tignanelli , Jared D. Huling

Revealing relationships between genes and disease phenotypes is a critical problem in biomedical studies. This problem has been challenged by the heterogeneity of diseases. Patients of a perceived same disease may form multiple subgroups,…

统计方法学 · 统计学 2022-11-30 Yifan Sun , Ziye Luo , Xinyan Fan

The identification of heterogeneous treatment effects (HTE) across subgroups is of significant interest in clinical trial analysis. Several state-of-the-art HTE estimation methods, including causal forests, apply recursive partitioning for…

统计方法学 · 统计学 2025-06-10 Vik Shirvaikar , Andrea Storås , Xi Lin , Chris Holmes

Chronic rhinosinusitis (CRS) is a common heterogeneous inflammatory disorder that causes substantial morbidity and healthcare costs. CRS is difficult to identify early from routine encounters, as symptom presentations overlap with common…

Personalized diagnoses have not been possible due to sear amount of data pathologists have to bear during the day-to-day routine. This lead to the current generalized standards that are being continuously updated as new findings are…

计算机视觉与模式识别 · 计算机科学 2021-10-27 Jialun Wu , Zeyu Gao , Haichuan Zhang , Ruonan Zhang , Tieliang Gong , Chunbao Wang , Chen Li

Owing to the advantages of increased accuracy and the potential to detect unseen patterns, provided by data mining techniques they have been widely incorporated for standard classification problems. They have often been used for high…

机器学习 · 计算机科学 2022-10-05 Anirudha Rayasam , Nagamma Patil

The objective of this study is to introduce methodology for studying longitudinal claims data observed at the patient level, with inference on the heterogeneity of healthcare utilization behaviors within large healthcare systems such as…

应用统计 · 统计学 2016-03-04 Ross P. Hilton , Nicoleta Serban , Richard Y. Zheng

Recent years, large scale clinical data like patient surveys and medical record data are playing an increasing role in medical data science. These large-scale clinical data, collectively referred to as "real-world data (RWD)". It is…

统计方法学 · 统计学 2024-02-23 Guanwenqing He , Ke Wan , Kazushi Maruo , Toshio Shimokawa

Mining Electronic Health Records (EHRs) becomes a promising topic because of the rich information they contain. By learning from EHRs, machine learning models can be built to help human experts to make medical decisions and thus improve…

机器学习 · 计算机科学 2021-01-19 Zheng Liu , Xiaohan Li , Hao Peng , Lifang He , Philip S. Yu

Most current recommender systems used the historical behaviour data of user to predict user' preference. However, it is difficult to recommend items to new users accurately. To alleviate this problem, existing user cold start methods either…

信息检索 · 计算机科学 2021-08-06 Ziyi Wang , Wendong Xiao , Yu Li , Zulong Chen , Zhi Jiang

The rapid development of the mobile Internet and the Internet of Things is leading to a diversification of user devices and the emergence of new mobile applications on a regular basis. Such applications include those that are…

计算工程、金融与科学 · 计算机科学 2024-08-13 Xirui Tang , Zeyu Wang , Xiaowei Cai , Honghua Su , Changsong Wei

The distribution of health care payments to insurance plans has substantial consequences for social policy. Risk adjustment formulas predict spending in health insurance markets in order to provide fair benefits and health care coverage for…

应用统计 · 统计学 2021-02-25 Anna Zink , Sherri Rose
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