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Statistical and probabilistic reasoning enlightens our judgments about uncertainty and the chance or beliefs on the occurrence of random events in everyday life. Therefore, there are scientists working with Probability and Statistics in…

Identifying patient subgroups with different treatment responses is an important task to inform medical recommendations, guidelines, and the design of future clinical trials. Existing approaches for treatment effect estimation primarily…

统计方法学 · 统计学 2025-12-10 Vincent Jeanselme , Chang Ho Yoon , Fabian Falck , Brian Tom , Jessica Barrett

This paper uses predictive densities obtained via mixed causal-noncausal autoregressive models to evaluate the statistical sustainability of Brazilian inflation targeting system with the tolerance bounds. The probabilities give an…

计量经济学 · 经济学 2022-07-26 Alain Hecq , Joao Issler , Elisa Voisin

Background: Variables in epidemiological observational studies are commonly subject to measurement error and misclassification, but the impact of such errors is frequently not appreciated or ignored. As part of the STRengthening Analytical…

In this paper we study the impact of exposure misclassification when cluster size is potentially informative (i.e., related to outcomes) and when misclassification is differential by cluster size. First, we show that misclassification in an…

We investigate the rates of drug resistance acquisition in a natural population using molecular epidemiological data from Bolivia. First, we study the rate of direct acquisition of double resistance from the double sensitive state within…

定量方法 · 定量生物学 2017-04-17 Guilherme S. Rodrigues , Andrew R. Francis , Scott A. Sisson , Mark M. Tanaka

We introduce a novel profile-based patient clustering model designed for clinical data in healthcare. By utilizing a method grounded on constrained low-rank approximation, our model takes advantage of patients' clinical data and digital…

机器学习 · 计算机科学 2023-08-24 Dongjin Choi , Andy Xiang , Ozgur Ozturk , Deep Shrestha , Barry Drake , Hamid Haidarian , Faizan Javed , Haesun Park

Clustering is an essential data mining tool that aims to discover inherent cluster structure in data. For most applications, applying clustering is only appropriate when cluster structure is present. As such, the study of clusterability,…

机器学习 · 统计学 2018-10-30 A. Adolfsson , M. Ackerman , N. C. Brownstein

Vaccination remains a cornerstone of global public health, yet the COVID-19 pandemic exposed how online misinformation, political polarization, and declining institutional trust can undermine immunization efforts. Most of the prior…

计算机与社会 · 计算机科学 2026-04-22 Geovana S. de Oliveira , Ana P. C. Silva , Fabricio Murai , Carlos H. G. Ferreira

Although co/multi-morbidities are associated with significant increase in mortality, the lack of appropriate quantitative exploratory techniques often impede their analysis. In the current study, we study the clustering of multimorbid…

定量方法 · 定量生物学 2018-07-13 Shatrunjai P. Singh , Swagata Karkare , Sudhir M. Baswan , Vijendra P. Singh

One difficulty for real-time tracking of epidemics is related to reporting delay. The reporting delay may be due to laboratory confirmation, logistic problems, infrastructure difficulties and so on. The ability to correct the available…

Measurement error in observational datasets can lead to systematic bias in inferences based on these datasets. As studies based on observational data are increasingly used to inform decisions with real-world impact, it is critical that we…

机器学习 · 统计学 2019-01-29 Roy Adams , Yuelong Ji , Xiaobin Wang , Suchi Saria

The Network scale-up method is commonly used to overcome difficulties in estimating the size of hard-to-reach populations. The method uses indirect information based on social network of each participant taken from the general population,…

统计计算 · 统计学 2018-04-16 Leonardo S Bastos , Natalia S Paiva , Francisco I Bastos , Daniel A M Villela

The possibility of unmeasured confounding is one of the main limitations for causal inference from observational studies. There are different methods for (partially) empirically assessing the plausibility of unconfoundedness. However, most…

统计方法学 · 统计学 2025-10-28 Fernando Pires Hartwig , Kate Tilling , George Davey Smith

Rare populations, such as endangered animals and plants, drug users and individuals with rare diseases, tend to cluster in regions. Adaptive cluster sampling is generally applied to obtain information from clustered and sparse populations…

An aggregate data meta-analysis is a statistical method that pools the summary statistics of several selected studies to estimate the outcome of interest. When considering a continuous outcome, typically each study must report the same…

统计方法学 · 统计学 2022-06-22 Sean McGrath , XiaoFei Zhao , Zhi Zhen Qin , Russell Steele , Andrea Benedetti

Clustering multimorbidity has been a global research priority in recent years. Existing studies usually identify these clusters using one of several popular clustering methods and then explore various characteristics of these clusters,…

应用统计 · 统计学 2025-05-06 Sohan Seth , Nazir Lone , Niels Peek , Bruce Guthrie

We study the large sample behavior of a convex clustering framework, which minimizes the sample within cluster sum of squares under an~$\ell_1$ fusion constraint on the cluster centroids. This recently proposed approach has been gaining in…

统计方法学 · 统计学 2016-12-30 Peter Radchenko , Gourab Mukherjee

Chest X-rays are the most commonly performed diagnostic examination to detect cardiopulmonary abnormalities. However, the presence of bony structures such as ribs and clavicles can obscure subtle abnormalities, resulting in diagnostic…

图像与视频处理 · 电气工程与系统科学 2021-05-10 Sivaramakrishnan Rajaraman , Ghada Zamzmi , Les Folio , Philip Alderson , Sameer Antani

In many situations it is desirable to identify clusters that differ with respect to only a subset of features. Such clusters may represent homogeneous subgroups of patients with a disease, such as cancer or chronic pain. We define a…

统计方法学 · 统计学 2014-07-14 Qian Liu , Guanhua Chen , Michael R. Kosorok , Eric Bair