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相关论文: Clustering Schemes on the Torus with Application t…

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RNA structure determination is essential for understanding its biological functions. However, the reconstruction process often faces challenges, such as atomic clashes, which can lead to inaccurate models. To address these challenges, we…

生物大分子 · 定量生物学 2026-03-04 Menghao Wu , Zhigang Yao

There are several cutting edge applications needing PCA methods for data on tori and we propose a novel torus-PCA method with important properties that can be generally applied. There are two existing general methods: tangent space PCA and…

统计方法学 · 统计学 2015-11-17 Benjamin Eltzner , Stephan Huckemann , Kanti V. Mardia

We study clustering on graphs with multiple edge types. Our main motivation is that similarities between objects can be measured in many different metrics. For instance similarity between two papers can be based on common authors, where…

社会与信息网络 · 计算机科学 2011-09-09 Matthew Rocklin , Ali Pinar

Unsupervised clustering algorithms for vectors has been widely used in the area of machine learning. Many applications, including the biological data we studied in this paper, contain some boundary datapoints which show combination…

机器学习 · 计算机科学 2022-05-23 Yingcong Li , Chandra Sekhar Mukherjee , Jiapeng Zhang

The paper concerns clustering with respect to the shape and size of 2D contours that are boundaries of cross-sections of 3D objects of revolution. We propose a number of similarity measures based on combined disparate Procrustes analysis…

计算机视觉与模式识别 · 计算机科学 2021-11-15 Agnieszka Kaliszewska , Monika Syga

Spectral clustering is a fundamental technique in the field of data mining and information processing. Most existing spectral clustering algorithms integrate dimensionality reduction into the clustering process assisted by manifold learning…

机器学习 · 计算机科学 2014-11-25 Xiaojun Chang , Feiping Nie , Zhigang Ma , Yi Yang , Xiaofang Zhou

We consider a generalized version of the correlation clustering problem, defined as follows. Given a complete graph $G$ whose edges are labeled with $+$ or $-$, we wish to partition the graph into clusters while trying to avoid errors: $+$…

数据结构与算法 · 计算机科学 2016-05-25 Gregory J. Puleo , Olgica Milenkovic

There is a growing interest in characterizing circular data found in biological systems. Such data are wide ranging and varied, from signal phase in neural recordings to nucleotide sequences in round genomes. Traditional clustering…

机器学习 · 计算机科学 2023-09-19 Xiaoxiao Sun , Paul Sajda

Clustering of proteins is of interest in cancer cell biology. This article proposes a hierarchical Bayesian model for protein (variable) clustering hinging on correlation structure. Starting from a multivariate normal likelihood, we enforce…

统计计算 · 统计学 2022-02-09 Riddhi Pratim Ghosh , Arnab Kumar Maity , Mohsen Pourahmadi , Bani K. Mallick

Cancer is a number of related yet highly heterogeneous diseases. Correct identification of cancer subtypes is critical for clinical decisions. The advance in sequencing technologies has made it possible to study cancer based on abundant…

应用统计 · 统计学 2018-11-27 Xiaochun Chen , Honggang Wang , Donghui Yan

This paper presents a clustering approach that allows for rigorous statistical error control similar to a statistical test. We develop estimators for both the unknown number of clusters and the clusters themselves. The estimators depend on…

统计理论 · 数学 2017-07-13 Michael Vogt , Matthias Schmid

Mixed data comprises both numeric and categorical features, and mixed datasets occur frequently in many domains, such as health, finance, and marketing. Clustering is often applied to mixed datasets to find structures and to group similar…

机器学习 · 计算机科学 2019-03-20 Amir Ahmad , Shehroz S. Khan

Unsupervised clustering of curves according to their shapes is an important problem with broad scientific applications. The existing model-based clustering techniques either rely on simple probability models (e.g., Gaussian) that are not…

机器学习 · 统计学 2015-04-03 Zhengwu Zhang , Debdeep Pati , Anuj Srivastava

Cluster analysis has proved to be an invaluable tool for the exploratory and unsupervised analysis of high dimensional datasets. Among methods for clustering, hierarchical approaches have enjoyed substantial popularity in genomics and other…

统计方法学 · 统计学 2014-11-20 Patrick K. Kimes , Yufeng Liu , D. Neil Hayes , J. S. Marron

RNA folding prediction remains challenging, but can be also studied using a topological mathematical approach. In the present paper, the mathematical method to compute the topological classification of RNA structures and based on matrix…

生物大分子 · 定量生物学 2025-08-11 Nicolò Cangiotti , Stefano Grasso

Time series data, spanning applications ranging from climatology to finance to healthcare, presents significant challenges in data mining due to its size and complexity. One open issue lies in time series clustering, which is crucial for…

机器学习 · 计算机科学 2023-07-07 Jorge Marco-Blanco , Rubén Cuevas

In cancer research, clustering techniques are widely used for exploratory analyses and dimensionality reduction, playing a critical role in the identification of novel cancer subtypes, often with direct implications for patient management.…

统计方法学 · 统计学 2023-05-11 Lorenzo Masoero , Emma Thomas , Giovanni Parmigiani , Svitlana Tyekucheva , Lorenzo Trippa

Clustering of molecules on biological membranes is a widely observed phenomenon. In some cases, such as the clustering of Ras proteins on the membranes of mammalian cells, proper cell signaling is critically dependent on the maintenance of…

分子网络 · 定量生物学 2019-08-28 Martijn Wehrens , Pieter Rein ten Wolde , Andrew Mugler

Generative approaches to clustering provide information on geometric properties of clusters, whereas discriminative approaches provide boundaries between clusters. Ideas from both approaches are incorporated to present a fully unsupervised,…

机器学习 · 统计学 2026-04-28 Mackenzie R. Neal , Paul D. McNicholas , Arthur White

In many applications of shape analysis, lengths between some landmarks are constrained. For instance, biomolecules often have some bond lengths and some bond angles constrained, and variation occurs only along unconstrained bonds and…

统计方法学 · 统计学 2025-02-25 Kanti V. Mardia , Benjamin Eltzner , Stephan F. Huckemann
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