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Applying a ML approach to the temporal variability of the Spike protein sequence enables us to identify, classify and track emerging virus variants. Our analysis is unbiased, in the sense that it does not require any prior knowledge of the…

Recent re-opening policies in the US, following a period of social distancing measures, introduced a significant increase in daily COVID-19 infections, calling for a roll-back or substantial revisiting of these policies in many states. The…

物理与社会 · 物理学 2020-07-30 Chaoqi Yang , Ruijie Wang , Fangwei Gao , Dachun Sun , Jiawei Tang , Tarek Abdelzaher

The investment of time and resources for better strategies and methodologies to tackle a potential pandemic is key to deal with potential outbreaks of new variants or other viruses in the future. In this work, we recreated the scene of a…

机器学习 · 计算机科学 2021-04-22 Andrés L. Suárez-Cetrulo , Ankit Kumar , Luis Miralles-Pechuán

We introduce a theoretical framework that highlights the impact of physical distancing variables such as human mobility and physical proximity on the evolution of epidemics and, crucially, on the reproduction number. In particular, in…

物理与社会 · 物理学 2022-01-31 Fabio Vanni , David Lambert , Luigi Palatella

The current global health emergency triggered by the pandemic COVID-19 is one of the greatest challenges mankind face in this generation. Computational simulations have played an important role to predict the development of the current…

种群与进化 · 定量生物学 2020-06-11 Kok Yew Ng , Meei Mei Gui

During the COVID-19 pandemic, a major driver of new surges has been the emergence of new variants. When a new variant emerges in one or more countries, other nations monitor its spread in preparation for its potential arrival. The impact of…

种群与进化 · 定量生物学 2024-12-30 Majd Al Aawar , Srikar Mutnuri , Mansooreh Montazerin , Ajitesh Srivastava

In the present article we introduce an epidemiological model for the investigation of the spread of epidemics caused by viruses. The model is applied specifically to COVID-19, the disease caused by the SARS-Cov-2 virus (aka "novel…

种群与进化 · 定量生物学 2020-04-10 Rodrigo A. Schulz , Carlos H. Coimbra-Araújo , Samuel W. S. Costiche

The COVID-19 pandemic due to the SARS-CoV-2 coronavirus has directly impacted the public health and economy worldwide. To overcome this problem, countries have adopted different policies and non-pharmaceutical interventions for controlling…

We demonstrate an approach to replicate and forecast the spread of the SARS-CoV-2 (COVID-19) pandemic using the toolkit of probabilistic programming languages (PPLs). Our goal is to study the impact of various modeling assumptions and…

机器学习 · 统计学 2022-03-08 Swapneel Mehta , Noah Kasmanoff

Despite the progress in medical care, combined population-wide interventions (such as physical distancing, testing and contact tracing) are still crucial to manage the SARS-CoV-2 pandemic, aggravated by the emergence of new highly…

The evolution of many microbes and pathogens, including circulating viruses such as seasonal influenza, is driven by immune pressure from the host population. In turn, the immune systems of infected populations get updated, chasing viruses…

种群与进化 · 定量生物学 2022-06-01 Jacopo Marchi , Michael Lässig , Aleksandra M. Walczak , Thierry Mora

COVID-19 has affected the world tremendously. It is critical that biological experiments and clinical designs are informed by computational approaches for time- and cost-effective solutions. Comparative analyses particularly can play a key…

生物大分子 · 定量生物学 2020-04-10 Goksel Misirli

Given multiple new COVID-19 variants are continuously emerging, non-pharmaceutical interventions are still primary control strategies to curb the further spread of coronavirus. However, implementing strict interventions over extended…

种群与进化 · 定量生物学 2022-03-01 Xiao Zhou , Xiaohu Zhang , Paolo Santi , Carlo Ratti

Over a year after the start of the COVID-19 epidemics, we are still facing the virus and it is hard to correctly predict its future spread over weeks to come, as well as the impacts of potential political interventions. Current epidemic…

多智能体系统 · 计算机科学 2021-12-03 Benoit Doussin , Carole Adam , Didier Georges

The large-scale evolution of the SARS-CoV-2 virus has been marked by rapid turnover of genetic clades. New variants show intrinsic changes, notably increased transmissibility, as well as antigenic changes that reduce the cross-immunity…

种群与进化 · 定量生物学 2022-07-20 Matthijs Meijers , Denis Ruchnewitz , Marta Łuksza , Michael Lässig

A new coronavirus disease, called COVID-19, appeared in the Chinese region of Wuhan at the end of last year; since then the virus spread to other countries, including most of Europe. We propose a differential equation governing the…

种群与进化 · 定量生物学 2020-09-15 Giorgio Sonnino , Pasquale Nardone

The outbreak of mutant strains and vaccination behaviors have been the focus of recent epidemiological research, but most existing epidemic models failed to simultaneously capture viral mutation and consider the complexity and behavioral…

种群与进化 · 定量生物学 2026-01-16 Wenjie Zhang , Yusheng Li , Qin Li , Guojun Huang , Minyu Feng

In December 2019, a newly discovered SARS-CoV-2 virus was emerged from China and propagated worldwide as a pandemic. In the absence of preventive medicine or a ready to use vaccine, mathematical models can provide useful scientific insights…

种群与进化 · 定量生物学 2020-06-30 Indrajit Ghosh

The world has seen in 2020 an unprecedented global outbreak of SARS-CoV-2, a new strain of coronavirus, causing the COVID-19 pandemic, and radically changing our lives and work conditions. Many scientists are working tirelessly to find a…

信息检索 · 计算机科学 2020-05-18 Pierre Le Bras , Azimeh Gharavi , David A. Robb , Ana F. Vidal , Stefano Padilla , Mike J. Chantler