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At the end of 2020, policy responses to the SARS-CoV-2 outbreak have been shaken by the emergence of virus variants, impacting public health and policy measures worldwide. The emergence of these strains suspected to be more contagious, more…

神经与进化计算 · 计算机科学 2021-02-25 Aymeric Vie

In light of the continuing emergence of new SARS-CoV-2 variants and vaccines, we create a simulation framework for exploring possible infection trajectories under various scenarios. The situations of primary interest involve the interaction…

种群与进化 · 定量生物学 2022-01-10 Kory D. Johnson , Annemarie Grass , Daniel Toneian , Mathias Beiglböck , Jitka Polechová

The crisis caused by the COVID-19 outbreak around the globe raised an increasing concern about the ongoing emergence of variants of SARS-CoV-2 that may evade the immune response provided by vaccines. New variants appear due to mutation, and…

种群与进化 · 定量生物学 2022-12-14 M. Ahumada , A. Ledesma-Araujo , Leonardo Gordillo , Juan F. Marín

Accurate and reliable forecasting of emerging dominant severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants enables policymakers and vaccine makers to get prepared for future waves of infections. The last three waves of…

种群与进化 · 定量生物学 2022-10-19 Jiahui Chen , Rui Wang , Yuta Hozumi , Gengzhuo Liu , Yuchi Qiu , Xiaoqi Wei , Guo-Wei Wei

After more than 6 million deaths worldwide, the ongoing vaccination to conquer the COVID-19 disease is now competing with the emergence of increasingly contagious mutations, repeatedly supplanting earlier strains. Following the near-absence…

种群与进化 · 定量生物学 2022-05-09 Fabian Jan Schwarzendahl , Jens Grauer , Benno Liebchen , Hartmut Löwen

How will the novel coronavirus evolve? I study a simple epidemiological model, in which mutations may change the properties of the virus and its associated disease stochastically and antigenic drifts allow new variants to partially evade…

综合经济学 · 经济学 2022-04-27 Patrick Mellacher

A novel coronavirus disease has emerged (later named COVID-19) and caused the world to enter a new reality, with many direct and indirect factors influencing it. Some are human-controllable (e.g. interventional policies, mobility and the…

机器学习 · 计算机科学 2021-01-12 Haonan Wu , Rajarshi Banerjee , Indhumathi Venkatachalam , Daniel Percy-Hughes , Praveen Chougale

The COVID-19 pandemic has severely impacted health systems and economies worldwide. Significant global efforts are therefore ongoing to improve vaccine efficacies, optimize vaccine deployment, and develop new antiviral therapies to combat…

种群与进化 · 定量生物学 2021-12-21 Rajat Desikan , Pranesh Padmanabhan , Andrzej M. Kierzek , Piet H. van der Graaf

CoV2019 has evolved to be much more dangerous than CoV2003. Experiments suggest that structural rearrangements dramatically enhance CoV2019 activity. We identify a new first stage of infection that precedes structural rearrangements by…

分子网络 · 定量生物学 2021-03-16 J. C. Phillips

The rapid spread of the Coronavirus SARS-2 is a major challenge that led almost all governments worldwide to take drastic measures to respond to the tragedy. Chief among those measures is the massive lockdown of entire countries and cities,…

In this work, we aim to study that the dynamics behavior for cumulative number of SARS-CoV-2 pandemic can provide information on the overall behavior of the spread over daily time.The cumulative data can be synthesized in an empirical form…

种群与进化 · 定量生物学 2020-11-16 Hamieh Mohamad , Doumit Mary , Toufaily Joumana , Hamieh Tayssir

The outbreak of the novel coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been continuously affecting human lives and communities around the world in many ways, from cities…

机器学习 · 计算机科学 2020-07-24 Ashkan Ebadi , Pengcheng Xi , Stéphane Tremblay , Bruce Spencer , Raman Pall , Alexander Wong

Mutating variants of COVID-19 have been reported across many US states since 2021. In the fight against COVID-19, it has become imperative to study the heterogeneity in the time-varying transmission rates for each variant in the presence of…

种群与进化 · 定量生物学 2022-05-17 K. D. Olumoyin , A. Q. M. Khaliq , K. M. Furati

We consider the dynamics of a virus spreading through a population that produces a mutant strain with the ability to infect individuals that were infected with the established strain. Temporary cross-immunity is included using a time delay,…

种群与进化 · 定量生物学 2023-02-16 Bruce Pell , Samantha Brozak , Tin Phan , Fuqing Wu , Yang Kuang

Genomic surveillance of SARS-CoV-2 has been instrumental in tracking the spread and evolution of the virus during the pandemic. The availability of SARS-CoV-2 molecular sequences isolated from infected individuals, coupled with phylodynamic…

应用统计 · 统计学 2021-08-31 Lorenzo Cappello , Jaehee Kim , Sifan Liu , Julia A. Palacios

In late 2019, COVID-19, a severe respiratory disease, emerged, and since then, the world has been facing a deadly pandemic caused by it. This ongoing pandemic has had a significant effect on different aspects of societies. The uncertainty…

神经与进化计算 · 计算机科学 2021-09-28 Mahdi Rahbar , Samaneh Yazdani

Motivated by epidemics such as COVID-19, we study the spread of a contagious disease when behavior responds to the disease's prevalence. We extend the SIR epidemiological model to include endogenous meeting rates. Individuals benefit from…

种群与进化 · 定量生物学 2023-09-25 Krishna Dasaratha

More than any other infectious disease epidemic, the COVID-19 pandemic has been characterized by the generation of large volumes of viral genomic data at an incredible pace due to recent advances in high-throughput sequencing technologies,…

Since the first wave of the COVID-19 pandemic, governments have applied restrictions in order to slow down its spreading. However, creating such policies is hard, especially because the government needs to trade-off the spreading of the…

机器学习 · 计算机科学 2022-05-03 Leonardo Lucio Custode , Giovanni Iacca

Coronavirus disease (COVID-19) which is caused by SARS-COV2 has become a pandemic. This disease is highly infectious and potentially fatal, causing a global public health concern. To contain the spread of COVID-19, governments are adopting…

物理与社会 · 物理学 2020-06-22 Sayantari Ghosh , Saumik Bhattacharya
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