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Community detection is considered as a fundamental task in analyzing social networks. Even though many techniques have been proposed for community detection, most of them are based exclusively on the connectivity structures. However, there…

社会与信息网络 · 计算机科学 2019-12-25 Hadi Zare , Mahdi Hajiabadi , Mahdi Jalili

The identification of cancer genes is a critical yet challenging problem in cancer genomics research. Existing computational methods, including deep graph neural networks, fail to exploit the multilayered gene-gene interactions or provide…

机器学习 · 计算机科学 2023-05-04 Michail Chatzianastasis , Michalis Vazirgiannis , Zijun Zhang

Inferring gene regulatory networks (GRNs) from single-cell RNA sequencing (scRNA-seq) data is a complex challenge that requires capturing the intricate relationships between genes and their regulatory interactions. In this study, we tackle…

机器学习 · 计算机科学 2024-07-26 Sindhura Kommu , Yizhi Wang , Yue Wang , Xuan Wang

Biomedical networks (or graphs) are universal descriptors for systems of interacting elements, from molecular interactions and disease co-morbidity to healthcare systems and scientific knowledge. Advances in artificial intelligence,…

机器学习 · 计算机科学 2025-02-07 Michelle M. Li , Kexin Huang , Marinka Zitnik

Personalized community detection aims to generate communities associated with user need on graphs, which benefits many downstream tasks such as node recommendation and link prediction for users, etc. It is of great importance but lack of…

信息检索 · 计算机科学 2020-09-08 Zheng Gao , Chun Guo , Xiaozhong Liu

This paper proposes a novel scalable community-based neural framework for graph learning. The framework learns the graph topology through the task of community detection and link prediction by optimizing with our proposed joint SBM loss…

社会与信息网络 · 计算机科学 2020-05-19 Zheng Chen , Xinli Yu , Yuan Ling , Xiaohua Hu

Understanding how small molecules perturb gene expression is essential for uncovering drug mechanisms, predicting off-target effects, and identifying repurposing opportunities. While prior deep learning frameworks have integrated multimodal…

机器学习 · 计算机科学 2026-01-01 Pascal Passigan , Kevin Zhu , Angelina Ning

Graph neural networks (GNNs) have attracted tremendous attention from the graph learning community in recent years. It has been widely adopted in various real-world applications from diverse domains, such as social networks and biological…

Graphs are fundamental data structures for modeling complex interactions in domains such as social networks, molecular structures, and biological systems. Graph-level tasks, which involve predicting properties or labels for entire graphs,…

机器学习 · 计算机科学 2026-04-10 Haoyang Li , Yuming Xu , Alexander Zhou , Yongqi Zhang , Jason Chen Zhang , Lei Chen , Qing Li

In genome-scale constraint-based metabolic models, gene deletion strategies are essential for achieving growth-coupled production, where cell growth and target metabolite synthesis occur simultaneously. Despite the inherently networked…

定量方法 · 定量生物学 2026-04-10 Ziwei Yang , Takeyuki Tamura

The integration of multi-omic data is pivotal for understanding complex diseases, but its high dimensionality and noise present significant challenges. Graph Neural Networks (GNNs) offer a robust framework for analyzing large-scale…

定量方法 · 定量生物学 2024-12-23 Heming Zhang , Di Huang , Yixin Chen , Fuhai Li

Graph Neural Networks (GNNs) have achieved remarkable success in various graph-based learning tasks. While their performance is often attributed to the powerful neighborhood aggregation mechanism, recent studies suggest that other…

机器学习 · 计算机科学 2024-12-11 Yushun Dong , Patrick Soga , Yinhan He , Song Wang , Jundong Li

Graph Neural Networks (GNNs) have recently shown to be powerful tools for representing and analyzing graph data. So far GNNs is becoming an increasingly critical role in software engineering including program analysis, type inference, and…

人工智能 · 计算机科学 2021-02-17 Jintang Li , Kun Xu , Liang Chen , Zibin Zheng , Xiao Liu

Discovery gene-disease links is important in biology and medicine areas, enabling disease identification and drug repurposing. Machine learning approaches accelerate this process by leveraging biological knowledge represented in ontologies…

机器学习 · 计算机科学 2025-04-14 Catarina Canastra , Cátia Pesquita

Community detection is a central problem in graph analysis, with applications ranging from network science to graph signal processing. In recent years, Graph Neural Networks (GNNs) have emerged as effective tools for learning…

数值分析 · 数学 2026-05-20 Roberto Cavoretto , Alessandra De Rossi , Enrico Montini

As a fundamental structure in real-world networks, in addition to graph topology, communities can also be reflected by abundant node attributes. In attributed community detection, probabilistic generative models (PGMs) have become the…

社会与信息网络 · 计算机科学 2022-05-31 Ren Ren , Jinliang Shao , Adrian N. Bishop , Wei Xing Zheng

The dramatic increase of complex, multi-step, and rapidly evolving attacks in dynamic networks involves advanced cyber-threat detectors. The GPML (Graph Processing for Machine Learning) library addresses this need by transforming raw…

机器学习 · 计算机科学 2025-05-15 Majed Jaber , Julien Michel , Nicolas Boutry , Pierre Parrend

Predicting drug-gene associations is crucial for drug development and disease treatment. While graph neural networks (GNN) have shown effectiveness in this task, they face challenges with data sparsity and efficient contrastive learning…

机器学习 · 计算机科学 2025-02-14 Jiayang Wu , Wensheng Gan , Philip S. Yu

Gene expression datasets offer insights into gene regulation mechanisms, biochemical pathways, and cellular functions. Additionally, comparing gene expression profiles between disease and control patients can deepen the understanding of…

机器学习 · 计算机科学 2025-03-27 Rita T. Sousa , Heiko Paulheim

Graph learning has rapidly evolved into a critical subfield of machine learning and artificial intelligence (AI). Its development began with early graph-theoretic methods, gaining significant momentum with the advent of graph neural…

机器学习 · 计算机科学 2025-11-10 Feng Xia , Ciyuan Peng , Jing Ren , Falih Gozi Febrinanto , Renqiang Luo , Vidya Saikrishna , Shuo Yu , Xiangjie Kong