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Unraveling the complexities of Gene Regulatory Networks (GRNs) is crucial for understanding cellular processes and disease mechanisms. Traditional computational methods often struggle with the dynamic nature of these networks. This study…

机器学习 · 计算机科学 2025-03-04 Hakan T. Otal , Abdulhamit Subasi , Furkan Kurt , M. Abdullah Canbaz , Yasin Uzun

Graphs may be used to represent many different problem domains -- a concrete example is that of detecting communities in social networks, which are represented as graphs. With big data and more sophisticated applications becoming widespread…

分布式、并行与集群计算 · 计算机科学 2017-04-03 Miguel E. Coimbra , Alexandre P. Francisco , Luis Veiga

Graphs are widely used in various fields of computer science. They have also found application in unrelated areas, leading to a diverse range of problems. These problems can be modeled as relationships between entities in various contexts,…

数据结构与算法 · 计算机科学 2024-05-20 Davide Rucci

Graph neural networks (GNNs) are powerful graph-based deep-learning models that have gained significant attention and demonstrated remarkable performance in various domains, including natural language processing, drug discovery, and…

机器学习 · 计算机科学 2023-06-06 Jaykumar Kakkad , Jaspal Jannu , Kartik Sharma , Charu Aggarwal , Sourav Medya

We propose a new multi-network-based strategy to integrate different layers of genomic information and use them in a coordinate way to identify driving cancer genes. The multi-networks that we consider combine transcription factor…

分子网络 · 定量生物学 2015-12-10 Laura Cantini , Enzo Medico , Santo Fortunato , Michele Caselle

Expression quantitative trait loci (eQTL) mapping aims to determine genomic regions that regulate gene transcription. Expression QTL is used to study the regulatory structure of normal tissues and to search for genetic factors in complex…

基因组学 · 定量生物学 2011-05-31 Andrey A. Shabalin

Predicting genetic perturbations enables the identification of potentially crucial genes prior to wet-lab experiments, significantly improving overall experimental efficiency. Since genes are the foundation of cellular life, building gene…

定量方法 · 定量生物学 2025-05-09 Changxi Chi , Jun Xia , Jingbo Zhou , Jiabei Cheng , Chang Yu , Stan Z. Li

This paper focuses on two fundamental tasks of graph analysis: community detection and node representation learning, which capture the global and local structures of graphs, respectively. In the current literature, these two tasks are…

社会与信息网络 · 计算机科学 2019-09-18 Fan-Yun Sun , Meng Qu , Jordan Hoffmann , Chin-Wei Huang , Jian Tang

Traditionally, community detection in graphs can be solved using spectral methods or posterior inference under probabilistic graphical models. Focusing on random graph families such as the stochastic block model, recent research has unified…

机器学习 · 统计学 2020-08-11 Zhengdao Chen , Xiang Li , Joan Bruna

Graph neural networks (GNNs) are able to achieve promising performance on multiple graph downstream tasks such as node classification and link prediction. Comparatively lesser work has been done to design GNNs which can operate directly for…

社会与信息网络 · 计算机科学 2021-10-20 Sambaran Bandyopadhyay , Vishal Peter

Graph Neural Networks (GNNs) have gained traction in the complex domain of drug discovery because of their ability to process graph-structured data such as drug molecule models. This approach has resulted in a myriad of methods and models…

机器学习 · 计算机科学 2025-09-10 Katherine Berry , Liang Cheng

Graph Neural Networks (GNNs) are powerful models that can manage complex data sources and their interconnection links. One of GNNs' main drawbacks is their lack of interpretability, which limits their application in sensitive fields. In…

机器学习 · 计算机科学 2026-03-24 Salvatore Calderaro , Domenico Amato , Giosuè Lo Bosco , Riccardo Rizzo , Filippo Vella

Graph neural networks (GNNs) have witnessed an unprecedented proliferation in tackling several problems in computer vision, computer-aided diagnosis, and related fields. While prior studies have focused on boosting the model accuracy,…

机器学习 · 计算机科学 2021-09-07 Mohammed Amine Gharsallaoui , Islem Rekik

Community detection is a fundamental problem in machine learning. While deep learning has shown great promise in many graphrelated tasks, developing neural models for community detection has received surprisingly little attention. The few…

机器学习 · 计算机科学 2019-09-27 Oleksandr Shchur , Stephan Günnemann

In recent years, Graph Neural Networks (GNNs), which can naturally integrate node information and topological structure, have been demonstrated to be powerful in learning on graph data. These advantages of GNNs provide great potential to…

信息检索 · 计算机科学 2019-11-26 Wenqi Fan , Yao Ma , Qing Li , Yuan He , Eric Zhao , Jiliang Tang , Dawei Yin

Graphs can model complex relationships between objects, enabling a myriad of Web applications such as online page/article classification and social recommendation. While graph neural networks(GNNs) have emerged as a powerful tool for graph…

机器学习 · 计算机科学 2023-02-28 Zemin Liu , Xingtong Yu , Yuan Fang , Xinming Zhang

Graph Machine Learning (GML) is receiving growing interest within the pharmaceutical and biotechnology industries for its ability to model biomolecular structures, the functional relationships between them, and integrate multi-omic datasets…

Community detection can reveal the underlying structure and patterns of complex networks, identify sets of nodes with specific functions or similar characteristics, and study the evolution process and development trends of networks. Despite…

社会与信息网络 · 计算机科学 2024-12-05 Jiaqi Yao , Lewis Mitchell

The integration of knowledge graphs and graph machine learning (GML) in genomic data analysis offers several opportunities for understanding complex genetic relationships, especially at the RNA level. We present a comprehensive approach for…

人工智能 · 计算机科学 2024-08-06 Shivika Prasanna , Ajay Kumar , Deepthi Rao , Eduardo Simoes , Praveen Rao

Graph Neural Networks (GNNs) have demonstrated remarkable efficacy in handling graph-structured data; however, they exhibit failures after deployment, which can cause severe consequences. Hence, conducting thorough testing before deployment…

软件工程 · 计算机科学 2025-12-23 Lichen Yang , Qiang Wang , Zhonghao Yang , Daojing He , Yu Li
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