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In the past decade, deep learning (DL) has achieved unprecedented success in numerous fields including computer vision, natural language processing, and healthcare. In particular, DL is experiencing an increasing development in applications…

计算机视觉与模式识别 · 计算机科学 2020-07-15 Liang Zhang , Johann Li , Ping Li , Xiaoyuan Lu , Peiyi Shen , Guangming Zhu , Syed Afaq Shah , Mohammed Bennarmoun , Kun Qian , Björn W. Schuller

Peptide therapeutics are widely regarded as the "third generation" of drugs, yet progress in peptide Machine Learning (ML) are hindered by the absence of standardized benchmarks. Here we present PepBenchmark, which unifies datasets,…

机器学习 · 计算机科学 2026-04-14 Jiahui Zhang , Rouyi Wang , Kuangqi Zhou , Tianshu Xiao , Lingyan Zhu , Yaosen Min , Yang Wang

Deep learning's rise since the early 2010s has transformed fields like computer vision and natural language processing and strongly influenced biomedical research. For drug discovery specifically, a key inflection - akin to vision's…

Machine learning (ML) approaches have demonstrated promising results in a wide range of healthcare applications. Data plays a crucial role in developing ML-based healthcare systems that directly affect people's lives. Many of the ethical…

Cognitive diagnosis has been developed for decades as an effective measurement tool to evaluate human cognitive status such as ability level and knowledge mastery. It has been applied to a wide range of fields including education, sport,…

人工智能 · 计算机科学 2024-07-09 Fei Wang , Weibo Gao , Qi Liu , Jiatong Li , Guanhao Zhao , Zheng Zhang , Zhenya Huang , Mengxiao Zhu , Shijin Wang , Wei Tong , Enhong Chen

In modern dynamic constantly developing society, more and more people suffer from chronic and serious diseases and doctors and patients need special and sophisticated medical and health support. Accordingly, prominent health stakeholders…

计算机与社会 · 计算机科学 2022-08-10 Mirjana Ivanovic , Serge Autexier , Miltiadis Kokkonidis

Clinical and biomedical research in low-resource settings often faces significant challenges due to the need for high-quality data with sufficient sample sizes to construct effective models. These constraints hinder robust model training…

Novel digital data sources and tools like machine learning (ML) and artificial intelligence (AI) have the potential to revolutionize data about development and can contribute to monitoring and mitigating humanitarian problems. The potential…

Digital Twin (DT) technology has emerged as a transformative approach in healthcare, but its application in personalized patient care remains limited. This paper aims to present a practical implementation of DT in the management of chronic…

定量方法 · 定量生物学 2025-07-17 Javad M Alizadeh , Mukesh K Patel , Huanmei Wu

The emergence and rapid development of the Internet of Medical Things (IoMT), an application of the Internet of Things into the medical and healthcare systems, have brought many changes and challenges to modern medical and healthcare…

密码学与安全 · 计算机科学 2019-02-11 Zhitao Guan , Zefang Lv , Xiaojiang Du , Longfei Wu , Mohsen Guizani

Background and Objectives: Reproducibility is a major challenge in developing machine learning (ML)-based solutions in computational pathology (CompPath). The NCI Imaging Data Commons (IDC) provides >120 cancer image collections according…

The astounding success made by artificial intelligence (AI) in healthcare and other fields proves that AI can achieve human-like performance. However, success always comes with challenges. Deep learning algorithms are data-dependent and…

图像与视频处理 · 电气工程与系统科学 2021-06-25 Johann Li , Guangming Zhu , Cong Hua , Mingtao Feng , BasheerBennamoun , Ping Li , Xiaoyuan Lu , Juan Song , Peiyi Shen , Xu Xu , Lin Mei , Liang Zhang , Syed Afaq Ali Shah , Mohammed Bennamoun

Drug addiction is a complex and pervasive global challenge that continues to pose significant public health concerns. Traditional approaches to anti-addiction drug discovery have struggled to deliver effective therapeutics, facing high…

生物大分子 · 定量生物学 2025-02-11 Dong Chen , Jian Jiang , Zhe Su , Guo-Wei Wei

As the amount of scientific data continues to grow at ever faster rates, the research community is increasingly in need of flexible computational infrastructure that can support the entirety of the data science lifecycle, including…

计算机与社会 · 计算机科学 2016-04-12 Robert L. Grossman , Allison Heath , Mark Murphy , Maria Patterson , Walt Wells

This study explores the application and performance of Transformational Machine Learning (TML) in drug discovery. TML, a meta learning algorithm, excels in exploiting common attributes across various domains, thus developing composite…

生物大分子 · 定量生物学 2023-10-02 Adnan Mahmud , Oghenejokpeme Orhobor , Ross D. King

Accurate and robust drug response prediction is of utmost importance in precision medicine. Although many models have been developed to utilize the representations of drugs and cancer cell lines for predicting cancer drug responses (CDR),…

定量方法 · 定量生物学 2023-11-22 Xiaoqiong Xia , Chaoyu Zhu , Yuqi Shan , Fan Zhong , Lei Liu

Recent advancements in Earth system science have been marked by the exponential increase in the availability of diverse, multivariate datasets characterised by moderate to high spatio-temporal resolutions. Earth System Data Cubes (ESDCs)…

While the field of medical image analysis has undergone a transformative shift with the integration of machine learning techniques, the main challenge of these techniques is often the scarcity of large, diverse, and well-annotated datasets.…

计算机视觉与模式识别 · 计算机科学 2025-11-18 Stefano Woerner , Arthur Jaques , Christian F. Baumgartner

Biomedical research centers can empower basic discovery and novel therapeutic strategies by leveraging their large-scale datasets from experiments and patients. This data, together with new technologies to create and analyze it, has ushered…

With recent advancements in AI and computation tools, intelligent paradigms emerged to empower different fields such as healthcare robots with new capabilities. Advanced AI robotic algorithms (e.g., reinforcement learning) can be trained…

机器人学 · 计算机科学 2024-07-25 Reza Abiri , Ali Rabiee , Sima Ghafoori , Anna Cetera