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In genome wide association studies (GWAS), researchers are often dealing with non-normally distributed traits or a mixture of discrete-continuous traits. However, most of the current region-based methods rely on multivariate linear mixed…

统计方法学 · 统计学 2021-09-30 Julien St-Pierre , Karim Oualkacha

Use of copula for the purpose of modeling dependence has been receiving considerable attention in recent times. On the other hand, search for multivariate copulas with desirable dependence properties also is an important area of research.…

统计方法学 · 统计学 2025-02-18 Subhajit Chattopadhyay

Uplift modeling estimates the causal effect of an intervention as the difference between potential outcomes under treatment and control, whereas counterfactual identification aims to recover the joint distribution of these potential…

机器学习 · 计算机科学 2025-12-10 Théo Verhelst , Gianluca Bontempi

Our article addresses the problem of flexibly estimating a multivariate density while also attempting to estimate its marginals correctly. We do so by proposing two new estimators that try to capture the best features of mixture of normals…

统计方法学 · 统计学 2009-01-05 Paolo Giordani , Xiuyan Mun , Robert Kohn

The Cox regression, a semi-parametric method of survival analysis, is extremely popular in biomedical applications. The proportional hazards assumption is a key requirement in the Cox model. To accommodate non-proportional hazards, we…

统计方法学 · 统计学 2022-06-13 Alexander Begun , Elena Kulinskaya

Survival models incorporating cure fractions, commonly known as cure fraction models or long-term survival models, are widely employed in epidemiological studies to account for both immune and susceptible patients in relation to the failure…

统计方法学 · 统计学 2023-11-14 Agatha Rodrigues , Patrick Borges

In competing risks models, the joint distribution of the event times is not identifiable even when the margins are fully known, which has been referred to as the "identifiability crisis in competing risks analysis" (Crowder, 1991). We model…

统计理论 · 数学 2013-05-14 Maik Schwarz , Geurt Jongbloed , Ingrid Van Keilegom

Copulas are a powerful tool for modeling multivariate distributions as they allow to separately estimate the univariate marginal distributions and the joint dependency structure. However, known parametric copulas offer limited flexibility…

机器学习 · 统计学 2021-11-11 Tim Janke , Mohamed Ghanmi , Florian Steinke

This article presents factor copula approaches to model temporal dependency of non-Gaussian (continuous/discrete) longitudinal data. Factor copula models are canonical vine copulas which explain the underlying dependence structure of a…

统计方法学 · 统计学 2025-02-18 Subhajit Chattopadhyay

We introduce a copula mixture model to perform dependency-seeking clustering when co-occurring samples from different data sources are available. The model takes advantage of the great flexibility offered by the copulas framework to extend…

统计方法学 · 统计学 2012-07-03 Melanie Rey , Volker Roth

Graphical models are commonly used tools for modeling multivariate random variables. While there exist many convenient multivariate distributions such as Gaussian distribution for continuous data, mixed data with the presence of discrete…

机器学习 · 统计学 2014-04-30 Jianqing Fan , Han Liu , Yang Ning , Hui Zou

In dependently censored survival data, the usual assumption of independent censoring or an incorrect specification of the correlation between the event and censoring times can bias marginal survival inference. Likelihood-based estimation of…

统计方法学 · 统计学 2026-04-07 Hyun-Soo Zhang , Inkyung Jung , Chung Mo Nam

This paper proposes a unified version of survival models that accounts for both zero-adjustment and cure proportions in various latent competing causes, useful in data where survival times may be zero or cure proportions are present. These…

We propose a comprehensive Bayesian joint modeling framework for zero-inflated longitudinal count data and time-to-event outcomes, explicitly incorporating a cure fraction to account for subjects who never experience the event. The…

统计方法学 · 统计学 2025-08-27 Taban Baghfalaki , Mojtaba Ganjali

Use copula to model dependency of variable extends multivariate gaussian assumption. In this paper we first empirically studied copula regression model with continous response. Both simulation study and real data study are given. Secondly…

统计方法学 · 统计学 2021-01-05 Weijian Luo , Mai Wo

Recently, Serfling and Xiao (2007) extended the L-moment theory (Hosking, 1990) to the multivariate setting. In the present paper, we focus on the two-dimension random vectors to establish a link between the bivariate L-moments (BLM) and…

统计方法学 · 统计学 2011-06-20 Brahim Brahimi , Fateh Chebana , Abdelhakim Necir

We introduce a nonparametric estimator of the conditional survival function in the mixture cure model for right censored data when cure status is partially known. The estimator is developed for the setting of a single continuous covariate…

统计方法学 · 统计学 2024-02-13 Wende C. Safari , Ignacio López-de-Ullibarri , M. Amalia Jácome

Measuring a strength of dependence of random variables is an important problem in statistical practice. In this paper, we propose a new function valued measure of dependence of two random variables. It allows one to study and visualize…

统计方法学 · 统计学 2014-05-12 Teresa Ledwina

This paper presents a new copula to model dependencies between insurance entities, by considering how insurance entities are affected by both macro and micro factors. The model used to build the copula assumes that the insurance losses of…

统计理论 · 数学 2014-11-03 Samiha Ismail , Gao Yu , Gesine Reinert , Trevor Maynard

The goals in clinical and cohort studies often include evaluation of the association of a time-dependent binary treatment or exposure with a survival outcome. Recently, several impactful studies targeted the association between…

应用统计 · 统计学 2019-01-24 Daniel Nevo , Tsuyoshi Hamada , Shuji Ogino , Molin Wang