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We analyze an approach to managing the COVID-19 pandemic without shutting down the economy while staying within the capacity of the healthcare system. We base our analysis on a detailed heterogeneous epidemiological model, which takes into…

种群与进化 · 定量生物学 2020-05-12 David Gershon , Alexander Lipton , Hagai Levine

Epidemics of infectious diseases have accompanied humans for a long time and, depending on the scale, cause various undesirable social and economic consequences. During the ongoing COVID-19 pandemic, governments of many countries impose…

物理与社会 · 物理学 2020-05-07 Andrzej Szymkowiak , Piotr Kulawik , Kishokanth Jeganathan , Paulina Guzik

During the ongoing COVID-19 pandemic, mathematical models of epidemic spreading have emerged as powerful tools to produce valuable predictions of the evolution of the pandemic, helping public health authorities decide which intervention…

动力系统 · 数学 2021-11-18 Lorenzo Zino , Ming Cao

Epidemic spread in a population is traditionally modeled via compartmentalized models which represent the free evolution of disease in absence of any intervention policies. In addition, these models assume full observability of disease…

种群与进化 · 定量生物学 2021-06-16 Nitin Kamra , Yizhou Zhang , Sirisha Rambhatla , Chuizheng Meng , Yan Liu

We present a local spread model of disease transmission on a regular network and compare different control options ranging from treating the whole population to local control in a well-defined neighborhood of an infectious individual.…

生物物理 · 物理学 2015-05-30 Katarzyna Oles , Ewa Gudowska-Nowak , Adam Kleczkowski

When considering airborne epidemic spreading in social systems, a natural connection arises between mobility and epidemic contacts. As individuals travel, possibilities to encounter new people either at the final destination or during the…

物理与社会 · 物理学 2024-05-10 Jesús A. Moreno López , Sandro Meloni , Jose J. Ramasco

While many efforts are currently devoted to vaccines development and administration, social distancing measures, including severe restrictions such as lockdowns, remain fundamental tools to contain the spread of COVID-19. A crucial point…

系统与控制 · 电气工程与系统科学 2021-09-03 Mauro Bisiacco , Gianluigi Pillonetto

Almost every country in the world is battling to limit the spread of COVID-19. As the world strives to get an effective medication to control the disease, appropriate intervention measures, for now, remains one of the effective methods to…

种群与进化 · 定量生物学 2022-05-13 Samuel Okyere , Joseph Ackora-Prah , Ebenezer Bonyah , Kwaku Forkuoh Darkwah

Pandemic influenza has the epidemic potential to kill millions of people. While various preventive measures exist (i.a., vaccination and school closures), deciding on strategies that lead to their most effective and efficient use remains…

In the context of the ongoing Covid-19 pandemic, several reports and studies have attempted to model and predict the spread of the disease. There is also intense debate about policies for limiting the damage, both to health and to the…

物理与社会 · 物理学 2020-05-04 Harshad Khadilkar , Tanuja Ganu , Deva P Seetharam

The detection and management of diseases become quite complicated when pathogens contain asymptomatic phenotypes amongst their ranks, as evident during the recent COVID-19 pandemic. Spreading of diseases has been studied extensively under…

物理与社会 · 物理学 2021-10-27 Saptarshi Sinha , Deep Nath , Soumen Roy

This study explores the application of Pontryagin's Maximum Principle to derive optimal strategies for controlling the spread of COVID-19, leveraging a novel compartmental model to capture the disease dynamics. We prioritize three key…

Despite extensive work on the interplay between traffic dynamics and epidemic spreading, the control of epidemic spreading by routing strategies has not received adequate attention. In this paper, we study the impact of efficient routing…

物理与社会 · 物理学 2016-11-23 Han-Xin Yang , Zhi-Xi Wu

We devise a theoretical model for the optimal dynamical control of an infectious disease whose diffusion is described by the SVIR compartmental model. The control is realized through implementing social rules to reduce the disease's spread,…

最优化与控制 · 数学 2022-08-10 Alessandro Ramponi , Maria Elisabetta Tessitore

The main focus of this chapter is on public health control strategies which are currently the main way to mitigate COVID-19 pandemic. We introduce and compare compartmental models of increasing complexity for COVID-19 transmission to…

种群与进化 · 定量生物学 2020-12-14 Redouane Qesmi , Aayah Hammoumi

We study variants of the SEIR model for interpreting some qualitative features of the statistics of the Covid-19 epidemic in France. Standard SEIR models distinguish essentially two regimes: either the disease is controlled and the number…

种群与进化 · 定量生物学 2020-06-25 Jean Dolbeault , Gabriel Turinici

The death toll for Covid-19 may be reduced by dividing the population into two classes, the vulnerable and the fit, with different lockdown regimes. Instead of one reproduction number there now are four parameters. These make it possible to…

种群与进化 · 定量生物学 2020-10-05 Guus Balkema

The design of an efficient curing policy, able to stem an epidemic process at an affordable cost, has to account for the structure of the population contact network supporting the contagious process. Thus, we tackle the problem of…

最优化与控制 · 数学 2017-12-04 Stefania Ottaviano , Francesco De Pellegrini , Stefano Bonaccorsi , Piet Van Mieghem

The process of contagiousness spread modelling is well-known in epidemiology. However, the application of spread modelling to banking market is quite recent. In this work, we present a system of ordinary differential equations, simulating…

最优化与控制 · 数学 2018-02-19 Olena Kostylenko , Helena Sofia Rodrigues , Delfim F. M. Torres

Ever since the outbreak of the COVID-19 epidemic, various public health control strategies have been proposed and tested against the coronavirus SARS-CoV-2. We study three specific COVID-19 epidemic control models: the susceptible, exposed,…

系统与控制 · 电气工程与系统科学 2021-06-09 Zhe Xu , Bo Wu , Ufuk Topcu