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In this paper, based on geometric singular perturbation analysis of a quasi-one dimensional Poisson-Nernst-Planck model for ionic flows, we study the problem of zero current condition for ionic flows through membrane channels with a simple…

动力系统 · 数学 2020-09-22 Hamid Mofidi , Weishi Liu

In this work, the dependence of reversal potentials and zero-current fluxes on diffusion coefficients are examined for ionic flows through membrane channels. The study is conducted for the setup of a simple structure defined by the profile…

软凝聚态物质 · 物理学 2019-12-17 Bob Eisenberg , Weishi Liu , Hamid Mofidi

In this research, we explore how permanent charges affect the movement of ionic currents through ion channels. We use a quasi-one-dimensional classical Poisson-Nernst-Planck (PNP) model to study two types of ions, one positively charged and…

动力系统 · 数学 2023-12-29 Hamid Mofidi

The main goal of this work is to examine the qualitative effect of ion sizes via a steady-state boundary value problem. We study a one-dimensional version of a Poisson-Nernst-Planck system with a local hard-sphere potential model for ionic…

数学物理 · 物理学 2022-03-18 Weishi Liu , Hamid Mofidi

In this paper, we study effects of permanent charges on ion flows through membrane channels via a quasi-one-dimensional classical Poisson-Nernst-Planck system. This system includes three ion species, two cations with different valences and…

软凝聚态物质 · 物理学 2023-12-07 Ning Sun , Weishi Liu

A modified Poisson-Nernst-Planck system in a bounded domain with mixed Dirichlet-Neumann boundary conditions is analyzed. It describes the concentrations of ions immersed in a polar solvent and the correlated electric potential due to the…

偏微分方程分析 · 数学 2023-05-25 Ansgar Jüngel , Annamaria Massimini

The flow of ions through permeable channels causes voltage drop in physiological nanodomains such as synapses, dendrites and dendritic spines, and other protrusions. How the voltage changes around channels in these nanodomains has remained…

软凝聚态物质 · 物理学 2025-01-10 Frédéric Paquin-Lefebvre , David Holcman

We present a finite volume scheme for modeling the diffusion of charged particles, specifically ions, in constrained geometries using a degenerate Poisson-Nernst-Planck system with size exclusion yielding cross-diffusion. Our method…

数值分析 · 数学 2026-03-04 Clément Cancès , Maxime Herda , Annamaria Massimini

Ionic flow carries electrical signals for cells to communicate with each other. The permanent charge of an ion channel is a crucial protein structure for flow properties while boundary conditions play a role of the driving force. Their…

数值分析 · 数学 2021-06-09 Weizhang Huang , Weishi Liu , Yufei Yu

In this work, we examine effects of large permanent charges on ionic flow through ion channels based on a quasi-one dimensional Poisson-Nernst-Planck model. It turns out large positive permanent charges inhibit the flux of cation as…

定量方法 · 定量生物学 2017-12-20 Liwei Zhang , Bob Eisenberg , Weishi Liu

We have directly observed reversal of the polarity of charged surfaces in water upon the addition of tri- and quadrivalent ions using atomic force microscopy. The bulk concentration of multivalent ions at which charge inversion reversibly…

统计力学 · 物理学 2009-11-10 K. Besteman , M. A. G. Zevenbergen , H. A. Heering , S. G. Lemay

The problem of the one dimensional electro-diffusion of ions in a strong binary electrolyte is considered. In such a system the solute dissociates completely into two species of ions with unlike charges. The mathematical description…

化学物理 · 物理学 2012-03-28 Sandip Ghosal , Zhen Chen

We apply general variational techniques to the problem of the counterion distribution around highly charged objects where strong condensation of counterions takes place. Within a field-theoretic formulation using a fluctuating electrostatic…

软凝聚态物质 · 物理学 2009-11-07 Roland R. Netz , Henri Orland

We report here new electrical laws, derived from nonlinear electro-diffusion theory, about the effect of the local geometrical structure, such as curvature, on the electrical properties of a cell. We adopt the Poisson-Nernst-Planck (PNP)…

亚细胞过程 · 定量生物学 2017-11-22 Jerome Cartailler , Zeev Schuss , David Holcman

A parallel plate capacitor containing an electrolytic solution is the simplest model of a supercapacitor, or electric double layer capacitor. Using both analytical and numerical techniques, we solve the Poisson-Nernst-Planck equations for…

软凝聚态物质 · 物理学 2025-10-02 Ivan Palaia , Adelchi J. Asta , Megh Dutta , Patrick B. Warren , Benjamin Rotenberg , Emmanuel Trizac

We study a classical system of identically charged counter-ions near a planar wall carrying a uniform surface charge density. The equilibrium statistical mechanics of the system depends on a single dimensionless coupling parameter. A new…

软凝聚态物质 · 物理学 2019-01-21 I. Palaia , M. Trulsson , L. Samaj , E. Trizac

This work is concerned with the stationary Poisson--Nernst--Planck equation with a large parameter which describes a huge number of ions occupying an electrolytic region. Firstly, we focus on the model with a single specie of positive…

偏微分方程分析 · 数学 2023-11-20 Jhih-Hong Lyu , Chiun-Chang Lee , Tai-Chia Lin

We consider a nonlinear drift-diffusion system for multiple charged species in a porous medium in 2D and 3D with periodic microstructure. The system consists of a transport equation for the concentration of the species and Poisson's…

偏微分方程分析 · 数学 2022-06-16 Apratim Bhattacharya , Markus Gahn , Maria Neuss-Radu

Surface sensitive synchrotron x-ray scattering studies were performed to obtain the distribution of monovalent ions next to a highly charged interface. A lipid phosphate (dihexadecyl hydrogen-phosphate) was spread as a monolayer at the…

软凝聚态物质 · 物理学 2007-05-23 Wei Bu , David Vaknin , Alex Travesset

The transport and dispersion of multiple species of charged ions are central to many biological and physical processes, including electrokinetic ion separation. However, most theoretical studies of dispersion in channels have focused on…

软凝聚态物质 · 物理学 2026-05-04 Thakurdas Mahata , Anirban Chatterjee , Ameeya Kumar Nayak
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