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Bayesian model-averaged meta-analysis allows quantification of evidence for both treatment effectiveness $\mu$ and across-study heterogeneity $\tau$. We use the Cochrane Database of Systematic Reviews to develop discipline-wide empirical…

Drug overdose deaths, including those due to prescription opioids, represent a critical public health issue in the United States and worldwide. Artificial intelligence (AI) approaches have been developed and deployed to help prescribers…

Accurately predicting conditional average treatment effects (CATEs) is crucial in personalized medicine and digital platform analytics. Since the treatments of interest often cannot be directly randomized, observational data is leveraged to…

统计方法学 · 统计学 2024-11-05 Miruna Oprescu , Nathan Kallus

Alcohol Use Disorder (AUD) treatment presents high individual-level heterogeneity, with outcomes ranging from complete abstinence to persistent heavy drinking. This variability-driven by complex behavioral, social, and environmental…

Opioid misuse is a national epidemic and a significant drug related threat to the United States. While the scale of the problem is undeniable, estimates of the local prevalence of opioid misuse are lacking, despite their importance to…

统计方法学 · 统计学 2023-05-12 Staci A. Hepler , David Kline , Andrea Bonny , Erin McKnight , Lance A. Waller

We often seek to estimate the impact of an exposure naturally occurring or randomly assigned at the cluster-level. For example, the literature on neighborhood determinants of health continues to grow. Likewise, community randomized trials…

统计方法学 · 统计学 2021-07-08 Laura B. Balzer , Wenjing Zheng , Mark J. van der Laan , Maya L. Petersen

As an important problem in causal inference, we discuss the identification and estimation of treatment effects (TEs) under limited overlap; that is, when subjects with certain features belong to a single treatment group. We use a latent…

机器学习 · 统计学 2022-04-22 Pengzhou Wu , Kenji Fukumizu

Meta-analytic-predictive (MAP) priors have been proposed as a generic approach to deriving informative prior distributions, where external empirical data are processed to learn about certain parameter distributions. The use of MAP priors is…

统计方法学 · 统计学 2025-11-11 Christian Röver , Tim Friede

Economists are often interested in estimating averages with respect to distributions of unobservables, such as moments of individual fixed-effects, or average partial effects in discrete choice models. For such quantities, we propose and…

计量经济学 · 经济学 2021-09-07 Stéphane Bonhomme , Martin Weidner

Bayesian hierarchical models are well-suited to analyzing the often noisy data from electroencephalography experiments in cognitive neuroscience: these models provide an intuitive framework to account for structures and correlations in the…

定量方法 · 定量生物学 2022-08-17 Davide Turco , Conor Houghton

Long-term behavioral and health risk factors constitute a primary focus of research on the etiology of chronic diseases. Yet, identifying critical time-windows during which risk factors have the strongest impact on disease risk is…

统计方法学 · 统计学 2022-01-14 Maude Wagner , Francine Grodstein , Karen Leffondre , Cécilia Samieri , Cécile Proust-Lima

The cyclical and heterogeneous nature of many substance use disorders highlights the need to adapt the type or the dose of treatment to accommodate the specific and changing needs of individuals. The Adaptive Treatment for Alcohol and…

统计方法学 · 统计学 2020-05-22 William J. Artman , Ashkan Ertefaie , Kevin G. Lynch , James R. McKay , Brent A. Johnson

Joint models for a wide class of response variables and longitudinal measurements consist on a mixed-effects model to fit longitudinal trajectories whose random effects enter as covariates in a generalized linear model for the primary…

统计方法学 · 统计学 2014-07-03 Rolando De la Cruz , Cristian Meza , Ana Arribas-Gil , Raymond J. Carroll

Machine learning algorithms can sometimes exacerbate health disparities based on ethnicity, gender, and other factors. There has been limited work at exploring potential biases within algorithms deployed on a small scale, and/or within…

Automatic Pronunciation Assessment (APA) plays a vital role in Computer-assisted Pronunciation Training (CAPT) when evaluating a second language (L2) learner's speaking proficiency. However, an apparent downside of most de facto methods is…

音频与语音处理 · 电气工程与系统科学 2023-06-08 Fu-An Chao , Tien-Hong Lo , Tzu-I Wu , Yao-Ting Sung , Berlin Chen

The identification of factors associated with mental and behavioral disorders in early childhood is critical both for psychopathology research and the support of primary health care practices. Motivated by the Millennium Cohort Study, in…

统计方法学 · 统计学 2021-09-15 Luca Merlo , Lea Petrella , Nikos Tzavidis

The safe use of pharmaceuticals in food-producing animals is vital to protect animal welfare and human food safety. Adverse events (AEs) may signal unexpected pharmacokinetic or toxicokinetic effects, increasing the risk of violative…

机器学习 · 计算机科学 2025-10-03 Hossein Sholehrasa , Xuan Xu , Doina Caragea , Jim E. Riviere , Majid Jaberi-Douraki

Variational Autoencoders (VAEs) have experienced recent success as data-generating models by using simple architectures that do not require significant fine-tuning of hyperparameters. However, VAEs are known to suffer from…

机器学习 · 统计学 2020-07-22 Wei Cheng , Gregory Darnell , Sohini Ramachandran , Lorin Crawford

This study explored how lifestyle, personal background, and family history contribute to the risk of developing Alcohol Use Disorder (AUD). Survey data from the All of Us Program was utilized to extract information on AUD status, lifestyle,…

机器学习 · 计算机科学 2024-10-25 Chenlan Wang , Gaojian Huang , Yue Luo

Claims from observational studies often fail to replicate. A study was undertaken to assess the reliability of cohort studies used in a highly cited meta-analysis of the association between ambient nitrogen dioxide, NO2, and fine…