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Aggressive behavior in autistic inpatient youth often arises in temporally clustered bursts complicating efforts to distinguish external triggers from internal escalation. The sample population branching factor-the expected number of new…

The health effects of environmental exposures have been studied for decades, typically using standard regression models to assess exposure-outcome associations found in observational non-experimental data. We propose and illustrate a…

应用统计 · 统计学 2017-09-20 Marie-Abele C. Bind , Donald B. Rubin

Causal inference analyses often use existing observational data, which in many cases has some clustering of individuals. In this paper we discuss propensity score weighting methods in a multilevel setting where within clusters individuals…

应用统计 · 统计学 2020-12-24 Youjin Lee , Trang Q. Nguyen , Elizabeth A. Stuart

Causal inference in observational studies is notoriously difficult, due to the fact that the experimenter is not in charge of the treatment assignment mechanism. Many potential con- founding factors (PCFs) exist in such a scenario, and if…

应用统计 · 统计学 2015-09-15 Vadim von Brzeski , Matt Taddy , David Draper

In multi-condition EEG experiments, brain activity is recorded as subjects perform various tasks or are exposed to different stimuli. The recorded signals are commonly transformed into time-frequency representations, which often display…

统计方法学 · 统计学 2025-07-29 Xiaomeng Ju , Thaddeus Tarpey , Hyung G Park

Peer effects, in which the behavior of an individual is affected by the behavior of their peers, are posited by multiple theories in the social sciences. Other processes can also produce behaviors that are correlated in networks and groups,…

统计方法学 · 统计学 2021-02-16 Dean Eckles , Eytan Bakshy

Adverse childhood experiences (ACEs) have been linked to a wide range of negative health outcomes in adulthood. However, few studies have investigated what specific combinations of ACEs most substantially impact mental health. In this…

应用统计 · 统计学 2025-11-25 Ruizhe Zhang , Jooyoung Kong , Dylan S. Small , William Bekerman

Objective. We establish a principled method for inferring mental health related psychometric variables from neural and behavioral data using the Implicit Association Test (IAT) as the data generation engine, aiming to overcome the limited…

An important task in drug development is to identify patients, which respond better or worse to an experimental treatment. Identifying predictive covariates, which influence the treatment effect and can be used to define subgroups of…

统计方法学 · 统计学 2018-11-27 Marius Thomas , Björn Bornkamp , Katja Ickstadt

Opioid overdose rates have increased in the United States over the past decade and reflect a major public health crisis. Modeling and prediction of drug and opioid hotspots, where a high percentage of events fall in a small percentage of…

机器学习 · 统计学 2023-02-14 Xueying Liu , Jeremy Carter , Brad Ray , George Mohler

Multi-level normal hierarchical models, also interpreted as mixed effects models, play an important role in developing statistical theory in multi-parameter estimation for a wide range of applications. In this article, we propose a novel…

统计理论 · 数学 2025-11-18 Aditi Sen , Masayo Y. Hirose , Partha Lahiri

Electroencephalography (EEG)-based emotion recognition suffers from severe performance degradation when models are transferred across heterogeneous datasets due to physiological variability, experimental paradigm differences, and device…

机器学习 · 计算机科学 2026-03-31 Guangli Li , Canbiao Wu , Na Tian , Li Zhang , Zhen Liang

In recent years, the US has experienced an opioid epidemic with an unprecedented number of drugs overdose deaths. Research finds such overdose deaths are linked to neighborhood-level traits, thus providing opportunity to identify effective…

机器学习 · 计算机科学 2021-12-07 Sachin Gavali , Chuming Chen , Julie Cowart , Xi Peng , Shanshan Ding , Cathy Wu , Tammy Anderson

Estimating the conditional average treatment effect (CATE) from observational data is relevant for many applications such as personalized medicine. Here, we focus on the widespread setting where the observational data come from multiple…

机器学习 · 计算机科学 2024-06-05 Jonas Schweisthal , Dennis Frauen , Mihaela van der Schaar , Stefan Feuerriegel

Meta-analysis is a systematic approach for understanding a phenomenon by analyzing the results of many previously published experimental studies. It is central to deriving conclusions about the summary effect of treatments and interventions…

计算机与社会 · 计算机科学 2021-04-13 Lu Cheng , Dmitriy A. Katz-Rogozhnikov , Kush R. Varshney , Ioana Baldini

Introduction: Healthcare AI models often inherit biases from their training data. While efforts have primarily targeted bias in structured data, mental health heavily depends on unstructured data. This study aims to detect and mitigate…

Previous likelihood-based linear modeling of nutritional data has been limited by the availability of software that allows flexible error structures in the data. We demonstrate the use of a Bayesian modeling approach to the analysis of such…

统计理论 · 数学 2007-06-13 Andrew Lawson , Daniela Nitcheva

The opioid epidemic remains a major public health challenge in the United States, requiring a multi-pronged intervention approach to mitigate harms to communities. Given the heterogeneity of the epidemic across the country, it is crucial…

应用统计 · 统计学 2026-04-13 Abdulrahman A. Ahmed , M. Amin Rahimian , Qiushi Chen , Praveen Kumar

Motivation: Externalizing behaviors in children, such as aggression, hyperactivity, and defiance, are influenced by complex interplays between genetic predispositions and environmental factors, particularly parental behaviors. Unraveling…

定量方法 · 定量生物学 2025-12-25 Mengman Wei , Qian Peng

Diet plays a crucial role in health, and understanding the causal effects of dietary patterns is essential for informing public health policy and personalized nutrition strategies. However, causal inference in nutritional epidemiology faces…

统计方法学 · 统计学 2026-01-26 Dafne Zorzetto , Zizhao Xie , Julian Stamp , Arman Oganisian , Roberta De Vito