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相关论文: Optimal Scheduling of Anticipated COVID-19 Vaccina…

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In this study, we formulate a mathematical model incorporating age specific transmission dynamics of COVID-19 to evaluate the role of vaccination and treatment strategies in reducing the size of COVID-19 burden. Initially, we establish the…

种群与进化 · 定量生物学 2021-02-22 Bishal Chhetri , D. k. k. Vamsi , S Balasubramanian , Carani B Sanjeevi

This paper presents a study on a compartmental epidemic model for COVID-19, examining the stability of its equilibrium points upon the introduction of vaccination as a strategy to mitigate the spread of the disease. Initially, the SIQR…

数值分析 · 数学 2024-05-29 Leonardo R. S. Rodrigues , Felipe Gabrielli

With the invention of the COVID-19 vaccine, shipping and distributing are crucial in controlling the pandemic. In this paper, we build a mean-field variational problem in a spatial domain, which controls the propagation of pandemic by the…

最优化与控制 · 数学 2022-07-12 Wonjun Lee , Siting Liu , Wuchen Li , Stanley Osher

We consider a SIR model with vaccination strategy on a sparse configuration model random graph. We show the convergence of the system when the number of nodes grows and characterize the scaling limits. Then, we prove the existence of…

Motivated by the issue of COVID-19 mitigation, in this work we tackle the general problem of optimally controlling an epidemic outbreak of a communicable disease structured by time since exposure, by the aid of two types of control…

种群与进化 · 定量生物学 2024-05-13 Alberto d'Onofrio , Mimmo Iannelli , Piero Manfredi , Gabriela Marinoschi

We evaluate the efficiency of various heuristic strategies for allocating vaccines against COVID-19 and compare them to strategies found using optimal control theory. Our approach is based on a mathematical model which tracks the spread of…

Whenever countries are threatened by a pandemic, as is the case with the COVID-19 virus, governments should take the right actions to safeguard public health as well as to mitigate the negative effects on the economy. In this regard, there…

机器学习 · 计算机科学 2020-05-18 Luis Miralles-Pechuán , Fernando Jiménez , Hiram Ponce , Lourdes Martínez-Villaseñor

This paper utilizes a stochastic Susceptible-Infected-recovered (SIR) model with a non-linear incidence rate to perform a detailed mathematical study of optimal lock-down intensity and vaccination rate under the COVID-19 pandemic…

最优化与控制 · 数学 2022-09-29 Paramahansa Pramanik

Since the recent introduction of several viable vaccines for SARS-CoV-2, vaccination uptake has become the key factor that will determine our success in containing the COVID-19 pandemic. We argue that game theory and social network models…

Because a fast vaccination rollout against coronavirus disease 2019 (COVID-19) is critical to restore daily life and avoid virus mutations, it is tempting to have a relaxed vaccination-administration management system. However, a robust…

定量方法 · 定量生物学 2022-03-17 Jorge Medina , Roberto Rojas-Cessa , Vatcharapan Umpaichitra

We consider the problem of controlling an SIR-model epidemic by temporarily reducing the rate of contact within a population. The control takes the form of a multiplicative reduction in the contact rate of infectious individuals. The…

最优化与控制 · 数学 2021-06-29 David I. Ketcheson

We consider the problem of the optimal allocation of vaccination and protection measures for the Susceptible-Infected-Recovered-Infected (SIRI) epidemiological model, which generalizes the classical Susceptible-Infected-Recovered (SIR) and…

最优化与控制 · 数学 2025-05-09 Urmee Maitra , Ashish R. Hota , Rohit Gupta , Alfred O. Hero

In this paper we introduce an approach to the management of infectious disease diffusion through the formulation of a controlled compartmental SVIR (Susceptible-Vaccinated-Infected-Recovered) model. We consider a cost functional…

最优化与控制 · 数学 2023-11-28 Alessandro Ramponiand M. Elisabetta Tessitore

In this research paper we modify a classical SIR model to better adapt to the dynamics of COVID-19, that is we propose the heterogeneous SQAIRD model where COVID-19 spreads over a population of economic agents, namely: the elderly, adults…

最优化与控制 · 数学 2021-05-19 Elena Gubar , Laura Policardo , Edgar J. Sanchez Carrera , Vladislav Taynitskiy

This research is about COVID-19, which is a contagious virus that reached many countries, including Lebanon. Monitoring the outbreak, researchers have been involved in introducing COVID-19 targeting vaccines. Already facing financial and…

应用统计 · 统计学 2023-12-22 Sarkis Der Wartanian , Baydaa Al Ayoubi

This paper introduces a spatiotemporal SEIQR epidemic model governed by a system of reaction-diffusion partial differential equations that incorporates optimal control strategies. The model captures the transmission dynamics of an…

动力系统 · 数学 2025-07-29 Achraf Zinihi , Matthias Ehrhardt , Moulay Rchid Sidi Ammi

This paper deals with an SIR model with saturated incidence rate affected by inhibitory effect and saturated treatment function. Two control functions have been used, one for vaccinating the susceptible population and other for the…

动力系统 · 数学 2018-07-17 Jayanta Kumar Ghosh , Uttam Ghosh , M. H. A. Biswas , Susmita Sarkar

Recent Covid-19 pandemic has demonstrated the need of efficient epidemic outbreak management. We study the optimal control problem of minimizing the fraction of infected population by applying vaccination and treatment control strategies,…

社会与信息网络 · 计算机科学 2021-12-07 Jagtap Kalyani Devendra , Kundan Kandhway

Non-pharmacological interventions (NPIs), and in particular social distancing, in conjunction with the advent of effective vaccines at the end of 2020, aspired for the development of a protective immunity shield against the spread of…

This work introduces a novel epidemiological model that simultaneously considers multiple viral strains, reinfections due to waning immunity response over time and an optimal control formulation. This enables us to derive optimal mitigation…

系统与控制 · 电气工程与系统科学 2021-09-10 Edilson F. Arruda , Dayse H. Pastore , Clauda M. Dias , Shyam S. Das