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During a pandemic, there are conflicting demands arising from public health and economic cost. Lockdowns are a common way of containing infections, but they adversely affect the economy. We study the question of how to minimise the economic…

种群与进化 · 定量生物学 2021-04-28 Joseph Samuel , Supurna Sinha

Motivated by COVID-19, we develop and analyze a simple stochastic model for a disease spread in human population. We track how the number of infected and critically ill people develops over time in order to estimate the demand that is…

种群与进化 · 定量生物学 2022-05-10 Jakub Svoboda , Josef Tkadlec , Andreas Pavlogiannis , Krishnendu Chatterjee , Martin A. Nowak

We study the problem of a policymaker who aims at taming the spread of an epidemic while minimizing its associated social costs. The main feature of our model lies in the fact that the disease's transmission rate is a diffusive stochastic…

最优化与控制 · 数学 2020-11-04 Salvatore Federico , Giorgio Ferrari

We formulate an optimal control problem to determine the lockdown policy to curb an epidemic where other control measures are not available yet. We present a unified framework to model the epidemic and economy that allows us to study the…

系统与控制 · 电气工程与系统科学 2022-01-20 Jagtap Kalyani Devendra , Kundan Kandhway

The potential tradeoff between health outcomes and economic impact has been a major challenge in the policy making process during the COVID-19 pandemic. Epidemic-economic models designed to address this issue are either too aggregate to…

During the COVID-19 pandemic of 2019/2020, authorities have used temporary ad-hoc policy measures, such as lockdowns and mass quarantines, to slow its transmission. However, the consequences of widespread use of these unprecedented measures…

While many efforts are currently devoted to vaccines development and administration, social distancing measures, including severe restrictions such as lockdowns, remain fundamental tools to contain the spread of COVID-19. A crucial point…

系统与控制 · 电气工程与系统科学 2021-09-03 Mauro Bisiacco , Gianluigi Pillonetto

We analyze an approach to managing the COVID-19 pandemic without shutting down the economy while staying within the capacity of the healthcare system. We base our analysis on a detailed heterogeneous epidemiological model, which takes into…

种群与进化 · 定量生物学 2020-05-12 David Gershon , Alexander Lipton , Hagai Levine

Pandemic control measures like lock-down, restrictions on restaurants and gatherings, social-distancing have shown to be effective in curtailing the spread of COVID-19. However, their sustained enforcement has negative economic effects. To…

After the first lockdown in response to the COVID-19 outbreak, many countries faced difficulties in balancing infection control with economics. Due to limited prior knowledge, economists began researching this issue using cost-benefit…

种群与进化 · 定量生物学 2021-10-19 Tsuyoshi Hondou

As the COVID19 spreads across the world, prevention measures are becoming the essential weapons to combat the pandemic in the period of crisis. The lockdown measure is the most controversial one as it imposes an overwhelming impact on our…

物理与社会 · 物理学 2021-02-12 Yuting Fu , Haitao Xiang , Hanqing Jin , Ning Wang

In the context of the ongoing Covid-19 pandemic, several reports and studies have attempted to model and predict the spread of the disease. There is also intense debate about policies for limiting the damage, both to health and to the…

物理与社会 · 物理学 2020-05-04 Harshad Khadilkar , Tanuja Ganu , Deva P Seetharam

Social distancing has been the only effective way to contain the spread of an infectious disease prior to the availability of the pharmaceutical treatment. It can lower the infection rate of the disease at the economic cost. A pandemic…

应用统计 · 统计学 2020-12-07 Kexin Chen , Chi Seng Pun , Hoi Ying Wong

This paper combines a canonical epidemiology model of disease dynamics with government policy of lockdown and testing, and agents' decision to social distance in order to avoid getting infected. The model is calibrated with data on deaths…

综合经济学 · 经济学 2022-02-10 Shomak Chakrabarti , Ilia Krasikov , Rohit Lamba

Several non-pharmaceutical interventions have been proposed to control the spread of the COVID-19 pandemic. On the large scale, these empirical solutions, often associated with extended and complete lockdowns, attempt to minimize the costs…

物理与社会 · 物理学 2020-07-23 M. Serra , S. al-Mosleh , S. Ganga Prasath , V. Raju , S. Mantena , J. Chandra , S. Iams , L. Mahadevan

In this study, we present a new epidemiological model, with contamination from confirmed and unreported. We also compute equilibria and study their stability without intervention strategies. Optimal control theory has proven to be a…

种群与进化 · 定量生物学 2020-08-14 Fulgence Mansal , Mouhamadou A. M. T. Baldé , Alpha O. Bah

In this research paper we modify a classical SIR model to better adapt to the dynamics of COVID-19, that is we propose the heterogeneous SQAIRD model where COVID-19 spreads over a population of economic agents, namely: the elderly, adults…

最优化与控制 · 数学 2021-05-19 Elena Gubar , Laura Policardo , Edgar J. Sanchez Carrera , Vladislav Taynitskiy

We propose a simple model of spreading of some infection in an originally healthy population which is different from other models existing in the literature. In particular, we use an operator technique which allows us to describe in a…

种群与进化 · 定量生物学 2020-10-29 F. Bagarello , F. Gargano , F. Roccati

We propose a simple SIR model in order to investigate the impact of various confinement strategies on a most virulent epidemic. Our approach is motivated by the current COVID-19 pandemic. The main hypothesis is the existence of two…

种群与进化 · 定量生物学 2020-12-30 G. Nakamura , B. Grammaticos , M. Badoual

The COVID-19 pandemic has posed a policy making crisis where efforts to slow down or end the pandemic conflict with economic priorities. This paper provides mathematical analysis of optimal disease control policies with idealized…

最优化与控制 · 数学 2021-02-16 Aaron Z. Palmer , Zelda B. Zabinsky , Shan Liu
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