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相关论文: Optimal policies for mitigating pandemic costs

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To mitigate the impact of the pandemic, several measures include lockdowns, rapid vaccination programs, school closures, and economic stimulus. These interventions can have positive or unintended negative consequences. Current research to…

机器学习 · 计算机科学 2025-08-11 Gaurav Deshkar , Jayanta Kshirsagar , Harshal Hayatnagarkar , Janani Venugopalan

We analyze an approach to managing the COVID-19 pandemic without shutting down the economy while staying within the capacity of the healthcare system. We base our analysis on a detailed heterogeneous epidemiological model, which takes into…

种群与进化 · 定量生物学 2020-05-12 David Gershon , Alexander Lipton , Hagai Levine

Epidemic risk assessment poses inherent challenges, with traditional approaches often failing to balance health outcomes and economic constraints. This paper presents a data-driven decision support tool that models epidemiological dynamics…

应用统计 · 统计学 2025-11-24 Chang Zhai , Ping Chen , Zhuo Jin , David Pitt

Social distancing and isolation have been introduced widely to counter the COVID-19 pandemic. However, more moderate contact reduction policies become desirable owing to adverse social, psychological, and economic consequences of a complete…

Models for control of epidemics on local, global and small-world networks are considered, with only partial information accessible about the status of individuals and their connections. The main goal of an effective control measure is to…

物理与社会 · 物理学 2007-05-23 A. Kleczkowski , B. Dybiec , C. A. Gilligan

We analyze an optimal control version of a simple SIRS epidemiology model. The policy maker can adopt policies to diminish the contact rate between infected and susceptible individuals, at a specific economic cost. The arrival of a vaccine…

种群与进化 · 定量生物学 2020-06-09 Evangelos Magirou

Non-pharmaceutical interventions (NPIs) are crucial for controlling pandemics, but existing research often overlooks the heterogeneity of individual behavior, which can lead to inaccurate evaluations of the effectiveness of strategies. In…

物理与社会 · 物理学 2026-03-09 Xihan Zhang , Yuqing Liu , Chen Zhao , Guijun Li

The COVID-19 pandemic has proved to be one of the most disruptive public health emergencies in recent memory. Among non-pharmaceutical interventions, social distancing and lockdown measures are some of the most common tools employed by…

动力系统 · 数学 2021-02-16 Carl Corcoran , John Michael Clark

The mitigation of an infectious disease spreading has recently gained considerable attention from the research community. It may be obtained by adopting sanitary measurements social rules, together with an extensive vaccination campaign.…

社会与信息网络 · 计算机科学 2022-02-17 Francesco Petrizzelli , Pietro Hiram Guzzi , Tommaso Mazza

In this study, we formulate a mathematical model incorporating age specific transmission dynamics of COVID-19 to evaluate the role of vaccination and treatment strategies in reducing the size of COVID-19 burden. Initially, we establish the…

种群与进化 · 定量生物学 2021-02-22 Bishal Chhetri , D. k. k. Vamsi , S Balasubramanian , Carani B Sanjeevi

The effective control of the COVID-19 pandemic is one the most challenging issues of nowadays. The design of optimal control policies is perplexed from a variety of social, political, economical and epidemiological factors. Here, based on…

动力系统 · 数学 2023-03-16 Antonis Armaou , Bryce Katch , Lucia Russo , Constantinos Siettos

Modelling epidemics via classical population-based models suffers from shortcomings that so-called individual-based models are able to overcome, as they are able to take heterogeneity features into account, such as super-spreaders, and…

最优化与控制 · 数学 2022-05-16 C. Courtès , E. Franck , K. Lutz , L. Navoret , Y. Privat

We propose and analyse an optimal control problem where the control system is a mathematical model for tuberculosis that considers reinfection. The control functions represent the fraction of early latent and persistent latent individuals…

最优化与控制 · 数学 2014-10-13 Paula Rodrigues , Cristiana J. Silva , Delfim F. M. Torres

This paper proposes optimal lockdown management policies based on short-term prediction of active COVID-19 confirmed cases to ensure the availability of critical medical resources. The optimal time to start the lockdown from the current…

系统与控制 · 电气工程与系统科学 2022-03-08 Shuvrangshu Jana , Debasish Ghose

We adapt a SEIRD differential model with asymptomatic population and Covid deaths, which we call SEAIRD, to simulate the evolution of COVID-19, and add a control function affecting both the diffusion of the virus and GDP, featuring all…

物理与社会 · 物理学 2020-06-02 Andrea Aspri , Elena Beretta , Alberto Gandolfi , Etienne Wasmer

In this research, we develop a framework to analyze the interaction between the economy and the Covid-19 pandemic using an extension of SIR epidemic model. At the outset, we assume there are two health related investments including general…

最优化与控制 · 数学 2022-02-14 Zachariah Sinkala , Vajira Manathunga , Bichaka Fayissa

In this work, we provide a general mathematical formalism to study the optimal control of an epidemic, such as the COVID-19 pandemic, via incentives to lockdown and testing. In particular, we model the interplay between the government and…

种群与进化 · 定量生物学 2022-04-14 Emma Hubert , Thibaut Mastrolia , Dylan Possamaï , Xavier Warin

The rapid spread of the Coronavirus SARS-2 is a major challenge that led almost all governments worldwide to take drastic measures to respond to the tragedy. Chief among those measures is the massive lockdown of entire countries and cities,…

We analyse 'stop-and-go' containment policies that produce infection cycles as periods of tight lockdowns are followed by periods of falling infection rates. The subsequent relaxation of containment measures allows cases to increase again…

理论经济学 · 经济学 2021-11-22 Claudius Gros , Daniel Gros

During the Covid-19 pandemic a key role is played by vaccination to combat the virus. There are many possible policies for prioritizing vaccines, and different criteria for optimization: minimize death, time to herd immunity, functioning of…