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Time-varying networks are fast emerging in a wide range of scientific and business disciplines. Most existing dynamic network models are limited to a single-subject and discrete-time setting. In this article, we propose a mixed-effect…

统计方法学 · 统计学 2018-06-12 Jingfei Zhang , Will Wei Sun , Lexin Li

We present a new class of models for assessing the cell dynamics characterising muscular dystrophies. The proposed approach comprises a system of integro-differential equations for the statistical distributions, over a large patient cohort,…

偏微分方程分析 · 数学 2025-11-20 Tommaso Lorenzi , Horacio Tettamanti , Mattia Zanella

The Kuramoto phase diffusion equation is a nonlinear partial differential equation which describes the spatio-temporal evolution of a phase variable in an oscillatory reaction diffusion system. Synchronization manifests itself in a…

无序系统与神经网络 · 物理学 2009-03-30 Ralf Toenjes , Bernd Blasius

We consider the impact of stochastic perturbations on otherwise coherent oscillations of classical pulsators. The resulting dynamics are modelled by a driven damped harmonic oscillator subject to either an external or an internal forcing…

太阳与恒星天体物理 · 物理学 2020-01-22 P. P. Avelino , M. S. Cunha , W. J. Chaplin

The emergence of collective synchrony from an incoherent state is a phenomenon essentially described by the Kuramoto model. This canonical model was derived perturbatively, by applying phase reduction to an ensemble of heterogeneous,…

适应与自组织系统 · 物理学 2022-04-19 Iván León , Diego Pazó

We numerically investigate the role of mechanical stress in modifying the conductivity properties of the cardiac tissue and its impact in computational models for cardiac electromechanics. We follow a theoretical framework recently proposed…

组织与器官 · 定量生物学 2019-05-02 A. Loppini , A. Gizzi , R. Ruiz Baier , C. Cherubini , F. Fenton , S. Filippi

In this paper, we consider the monodomain model of cardiac electrophysiology. After an analysis of the well-posedness of the forward problem, we show that perfectly insulating regions (modeling ischemic regions in the cardiac tissue) can be…

偏微分方程分析 · 数学 2024-07-15 Andrea Aspri , Elena Beretta , Elisa Francini , Dario Pierotti , Sergio Vessella

Feedback loops are essential for regulating cell proliferation and maintaining the delicate balance between cell division and cell death. Thanks to the exact solution of a few simple models of cell growth it is by now clear that stochastic…

种群与进化 · 定量生物学 2023-03-07 Antonio Francesco Zirattu , Marta Biondo , Matteo Osella , Michele Caselle

We propose a mathematical and numerical model for the simulation of the heart function that couples cardiac electrophysiology, active and passive mechanics and hemodynamics, and includes reduced models for cardiac valves and the circulatory…

A stochastic model for a super-position of uncorrelated pulses with a random distribution of and correlations between amplitudes and velocities is analyzed. The pulses are assumed to move radially with fixed shape and amplitudes decreasing…

等离子体物理 · 物理学 2024-12-09 O. Paikina , J. M. Losada , A. Theodorsen , O. E. Garcia

Theoretical studies of synchronization are usually based on models of coupled phase oscillators which, when isolated, have constant angular frequency. Stochastic discrete versions of these uniform oscillators have also appeared in the…

数据分析、统计与概率 · 物理学 2012-01-30 Vladimir R. V. Assis , Mauro Copelli

We developed a novel patient-specific computational model for the numerical simulation of ventricular electromechanics in patients with ischemic cardiomyopathy (ICM). This model reproduces the activity both in sinus rhythm (SR) and in…

A new stochastic cellular automaton (CA) model of traffic flow, which includes slow-to-start effects and a driver's perspective, is proposed by extending the Burgers CA and the Nagel-Schreckenberg CA model. The flow-density relation of this…

统计力学 · 物理学 2009-11-10 Katsuhiro Nishinari , Minoru Fuku , Andreas Schadschneider

A deterministic cellular automaton rule defined on the Moore neighbourhood is studied as a model of epidemic propagation. The directed nature of the interaction between cells allows one to introduce the dependence on a disorder parameter…

统计力学 · 物理学 2007-05-23 M. Bezzi , R. Livi

The long time dynamics of large particles trapped in two inhomogeneous turbulent shear flows is studied experimentally. Both flows present a common feature, a shear region that separates two colliding circulations, but with different…

流体动力学 · 物理学 2016-03-02 N Machicoane , M López-Caballero , L Fiabane , J-F Pinton , M Bourgoin , J Burguete , R Volk

When modelling tissue-level cardiac electrophysiology, continuum approximations to the discrete cell-level equations are used to maintain computational tractability. One of the most commonly used models is represented by the bidomain…

计算工程、金融与科学 · 计算机科学 2012-08-22 Doug Bruce , Pras Pathmanathan , Jonathan P. Whiteley

Flow cytometry is a widespread single-cell measurement technology with a multitude of clinical and research applications. Interpretation of flow cytometry data is hard; the instrumentation is delicate and can not render absolute…

应用统计 · 统计学 2015-02-16 Jonas Wallin , Kerstin Johnsson , Magnus Fontes

In this paper we address the question of statistical model selection for a class of stochastic models of biological neural nets. Models in this class are systems of interacting chains with memory of variable length. Each chain describes the…

统计理论 · 数学 2018-12-19 A. Duarte , A. Galves , E. Löcherbach , G. Ost

We study existence of solutions in the variational sense for a class of stochastic phase-field models describing moving boundary problems. The models consist of stochastic reaction-diffusion equations with singular diffusion forced by a…

概率论 · 数学 2026-01-12 Amjad Saef , Wilhelm Stannat

The Expectation-Maximization (EM) algorithm is a popular choice for learning latent variable models. Variants of the EM have been initially introduced, using incremental updates to scale to large datasets, and using Monte Carlo (MC)…

机器学习 · 统计学 2022-03-22 Belhal Karimi , Ping Li