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Ordinary differential equation (ODE) is an important tool to study the dynamics of a system of biological and physical processes. A central question in ODE modeling is to infer the significance of individual regulatory effect of one signal…

统计方法学 · 统计学 2024-02-06 Xiaowu Dai , Lexin Li

Cortical neurons exhibit a hierarchy of timescales across brain regions in response to input stimuli, which is thought to be crucial for information processing of different temporal scales. Modeling studies suggest that both intra-regional…

神经元与认知 · 定量生物学 2024-12-24 Yang Qi , Jiexiang Wang , Weiyang Ding , Gustavo Deco , Viktor Jirsa , Wenlian Lu , Jianfeng Feng

Stroke-induced disturbances of large-scale cortical networks are known to be associated with the extent of motor deficits. We argue that identifying brain networks representative of motor behavior in the resting brain would provide…

神经元与认知 · 定量生物学 2019-07-24 Ozan Özdenizci , Timm Meyer , Felix Wichmann , Jan Peters , Bernhard Schölkopf , Müjdat Çetin , Moritz Grosse-Wentrup

By interpreting the forward dynamics of the latent representation of neural networks as an ordinary differential equation, Neural Ordinary Differential Equation (Neural ODE) emerged as an effective framework for modeling a system dynamics…

机器学习 · 计算机科学 2020-10-19 Daehoon Gwak , Gyuhyeon Sim , Michael Poli , Stefano Massaroli , Jaegul Choo , Edward Choi

We theoretically study the decoherence of a two-level quantum system coupled to noisy environments exhibiting linear and quadratic fluctuations within the framework of a stochastic Liouville equation. It is shown that the intrinsic energy…

量子物理 · 物理学 2024-07-26 Xiangji Cai , Yanyan Feng , Jing Ren , Yonggang Peng , Yujun Zheng

Spontaneous oscillations measured by Local field potentials (LFPs), electroencephalograms and magnetoencephalograms exhibits variety of oscillations spanning frequency band ($1-100$ Hz) in animals and humans. Both instantaneous power and…

神经元与认知 · 定量生物学 2025-02-25 Rakesh Sengupta , P V Raja Shekar

The temporal activity of many biological systems, including neural circuits, exhibits fluctuations simultaneously varying over a large range of timescales. The mechanisms leading to this temporal heterogeneity are yet unknown. Here we show…

无序系统与神经网络 · 物理学 2022-08-03 Merav Stern , Nicolae Istrate , Luca Mazzucato

Neurons are the central biological objects in understanding how the brain works. The famous Hodgkin-Huxley model, which describes how action potentials of a neuron are initiated and propagated, consists of four coupled nonlinear…

神经元与认知 · 定量生物学 2010-02-01 William Hanan , Dhagash Mehta , Guillaume Moroz , Sepanda Pouryahya

We continue the work of a series of previous studies of a mathematical model that describes the mean-field limit behavior of a homogeneous network of excitatory point spiking neurons. Contrary to other models, here noise is intrinsic to the…

神经元与认知 · 定量生物学 2017-07-20 Guillem Via

We present a computational assessment system that promotes the learning of basic rhythmic patterns. The system is capable of generating multiple rhythmic patterns with increasing complexity within various cycle lengths. For a generated…

多媒体 · 计算机科学 2021-09-10 Noel Alben , Ranjani H. G

Generative models of brain activity have been instrumental in testing hypothesized mechanisms underlying brain dynamics against experimental datasets. Beyond capturing the key mechanisms underlying spontaneous brain dynamics, these models…

神经元与认知 · 定量生物学 2024-11-18 Rishikesan Maran , Eli J. Müller , Ben D. Fulcher

We apply the framework of optimal nonlinear control to steer the dynamics of a whole-brain network of FitzHugh-Nagumo oscillators. Its nodes correspond to the cortical areas of an atlas-based segmentation of the human cerebral cortex, and…

神经元与认知 · 定量生物学 2021-09-08 Teresa Chouzouris , Nicolas Roth , Caglar Cakan , Klaus Obermayer

How intelligence arises from the brain is a central problem in science. A crucial aspect of intelligence is dealing with uncertainty -- developing good predictions about one's environment, and converting these predictions into decisions.…

神经元与认知 · 定量生物学 2024-06-13 Max Dabagia , Daniel Mitropolsky , Christos H. Papadimitriou , Santosh S. Vempala

The response of the Hodgkin-Huxley neuronal model subjected to stochastic uncorrelated spike trains originating from a large number of inhibitory and excitatory post-synaptic potentials is analyzed in detail. The model is examined in its…

无序系统与神经网络 · 物理学 2007-05-23 Stefano Luccioli , Thomas Kreuz , Alessandro Torcini

The aim of the present paper is to efficiently describe the membrane potential dynamics of neural populations formed by species having a high density difference in specific brain areas. We propose a hybrid model whose main ingredients are a…

神经元与认知 · 定量生物学 2015-10-06 Anna Cattani , Sergio Solinas , Claudio Canuto

In this work, we investigate the spike-adding mechanism in a class of three-dimensional fast-slow systems with three distinct timescales, inspired by the FitzHugh-Nagumo (FHN) model driven by periodic input. First, we numerically generate a…

动力系统 · 数学 2025-05-28 Pake Melland , Rodica Curtu , Zahra Aminzare

It has been proposed that neural noise in the cortex arises from chaotic dynamics in the balanced state: in this model of cortical dynamics, the excitatory and inhibitory inputs to each neuron approximately cancel, and activity is driven by…

无序系统与神经网络 · 物理学 2017-04-28 Nimrod Shaham , Yoram Burak

Synchronization in neural system plays an important role in many brain functions. Synchronization in the gamma frequency band (30Hz-100Hz) is involved in a variety of cognitive phenomena; abnormalities of the gamma synchronization are found…

神经元与认知 · 定量生物学 2021-04-26 Quynh-Anh Nguyen , Leonid L Rubchinsky

Many biological and neural systems can be seen as networks of interacting periodic processes. Importantly, their functionality depends on the emerging collective dynamics of the network. Synchrony of oscillations is one of the most…

适应与自组织系统 · 物理学 2020-05-29 Christian Bick , Marc Goodfellow , Carlo R. Laing , Erik A. Martens

Neural oscillations facilitate the functioning of the human brain in spatial and temporal dimensions at various frequencies. These oscillations feature a universal frequency architecture that is governed by brain anatomy, ensuring frequency…

神经元与认知 · 定量生物学 2025-02-10 ZhuQing Gong , XiNian Zuo