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Prostate cancer is one of the leading causes of cancer-related mortality among men in the U.S. We examined the role of neighborhood obesogenic attributes on prostate cancer risk and mortality in the Southern Community Cohort Study (SCCS).…

Obesity is a global health concern associated with high morbidity and mortality. Therapeutic strategies include synthetic drugs and surgery, which may entail high costs and serious complications. Plant-based medicinal agents offer an…

Obesity rates have been increasing over recent decades, causing significant concern among policy makers. Excess body fat, commonly measured by body mass index (BMI), is a major risk factor for several common disorders including diabetes and…

Assuming that there is feedback between an expanding cancer system and its organ-typical microenvironment, we argue here that such local tumor growth is guided by co-existence rather than competition with the surrounding tissue. We then…

Globally, the number of obese patients has doubled due to sedentary lifestyles and improper dieting. The tremendous increase altered human genetics, and health. According to the world health organization, Life expectancy dropped from 80 to…

The "obesity paradox" has been reported in several observational studies, where obesity was shown to be associated to a decreased mortality in individuals suffering from a chronic disease, such as diabetes or heart failure. Causal arguments…

Understanding biological phenomena requires a systemic approach that incorporates different mechanisms acting on different spatial and temporal scales, since in organisms the workings of all components, such as organelles, cells, and organs…

Overweight and obese individuals tend to have increased brain age, reflecting poorer brain health likely due to grey and white matter atrophy related to obesity. However, it is unclear if older brain age associated with obesity can be…

Obesity is defined as the excessive accumulation or abnormal distribution of body fat. According to data from World Obesity Atlas 2024, the increase in prevalence of obesity has become a major worldwide health problem in adults as well as…

Obesity, the leading cause of many non-communicable diseases, occurs mainly for eating more than our body requirements and lack of proper activity. So, being healthy requires heathy diet plans, especially for patients with comorbidities.…

In 2015 in the United States 612,000 persons died from cancer whereas only 470 died from tuberculosis (TB), a disease which was the main cause of death around 1900. How can one explain such a key discrepancy in treatment progress? A…

Maternal obesity is associated with increased risk of diabetes, cardiovascular disease and hypertension in adult offspring. Midlife hypercholesterolemia and hypertension are risk factors for Alzheimer's disease, suggesting that the ageing…

Overweight and obesity remain a major global public health concern and identifying the individualized patterns that increase the risk of future weight gains has a crucial role in preventing obesity and numerous sub-sequent diseases…

Significant overweight represents a major health problem in industrialized countries. Besides its known metabolic origins, this condition may also have an infectious cause, as recently postulated. Here, it is surmised that the potentially…

We consider the decision making by mammalian cells, looking them as dynamic systems with rhythms. We calculate the effective dimension of the cell division model of the healthy mammalian cells consistent with the data: it is described via a…

More than one-third of the adult population in the United States is obese. Obesity has been linked to factors such as, genetics, diet, physical activity and the environment. However, evidence indicating associations between the built…

The global surge in the cases of gastric cancer has prompted an investigation into the potential of gut microbiota as a predictive marker for the disease. The alterations in gut diversity are suspected to be associated with an elevated risk…

In the context of the global obesity epidemic, it is important to know who becomes obese and why. However, the processes that determine the changing shape of Body Mass Index (BMI) distributions in high-income societies are not…

A person's weight status can have profound implications on their life, ranging from mental health, to longevity, to financial income. At the societal level, "fat shaming" and other forms of "sizeism" are a growing concern, while increasing…

Aim: To assess the relationship between oral health and asthma. Methods: Data from 1,315 overweight or obese individuals, aged 40-65 years was used. Asthma was self-reported, while periodontitis, bleeding on probing (BOP), and plaque index…