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Germinal centres are anatomically defined lymphoid organ structures that mediate B cell affinity maturation and affect the quality of humoral immune responses. Mathematical models based on differential equations or agent-based simulations…

定量方法 · 定量生物学 2019-11-22 Lisa Buchauer , Hedda Wardemann

The adhesion of cells is mediated by receptors and ligands anchored in apposing membranes. A central question is how to characterize the binding affinity of these membrane-anchored molecules. For soluble molecules, the binding affinity is…

软凝聚态物质 · 物理学 2009-06-03 Heinrich Krobath , Bartosz Rozycki , Reinhard Lipowsky , Thomas R. Weikl

Motivated by quantum gravity and the CFT Distance Conjecture, we study infinite-distance limits in four-dimensional ${\cal N}=2$ superconformal field theories with higher-dimensional conformal manifolds and their AdS duals. We focus on…

高能物理 - 理论 · 物理学 2026-03-04 Fabio Mantegazza , Enrico Marchetto , Elli Pomoni , Torben Skrzypek , Timo Weigand

Rapidly increasing traffic demand has forced indoor operators to deploy more and more Wi-Fi access points (APs). As AP density increases, inter-AP interference rises and may limit the capacity. Alternatively, cellular technologies using…

信息论 · 计算机科学 2012-11-20 Du Ho Kang , Ki Won Sung , Jens Zander

Tunneling measurements of the temperature dependence of the electronic density of states (DOS) of ultrathin bilayers of Pb and Ag reveal that their superconducting energy gap, $\Delta (T)$, evolves similarly to BCS predictions despite the…

超导电性 · 物理学 2009-11-11 Zhenyi Long , M. D. Stewart , James M. Valles

Collective sensing by interacting cells is observed in a variety of biological systems, and yet a quantitative understanding of how sensory information is collectively encoded is lacking. Here we investigate the ATP-induced calcium dynamics…

细胞行为 · 定量生物学 2017-09-20 Garrett D Potter , Tommy A Byrd , Andrew Mugler , Bo Sun

For many viruses assembly and budding occur simultaneously during virion formation. Understanding the mechanisms underlying this process could promote biomedical efforts to block viral propagation and enable use of capsids in nanomaterials…

亚细胞过程 · 定量生物学 2014-03-11 Teresa Ruiz-Herrero , Michael F. Hagan

Symbiotic systems often include an asymptotic giant branch (AGB) star and a hot compact companion, such as a white dwarf, that are in close interaction. Due to the intense ultraviolet emission from the hot companion, the molecular content…

太阳与恒星天体物理 · 物理学 2024-08-13 M. Gómez-Garrido , V. Bujarrabal , J. Alcolea , A. Castro-Carrizo , J. Mikołajewska , M. Santander-García

Nascent adhesions are submicron transient structures promoting the early adhesion of cells to the extracellular matrix. Nascent adhesions typically consist of several tens of integrins, and serve as platforms for the recruitment and…

亚细胞过程 · 定量生物学 2021-01-19 Henning Stumpf , Andreja Ambriović-Ristov , Aleksandra Radenovic , Ana-Sunčana Smith

Since the current evidence of its existence is revealed only through its gravitational influence, the way dark matter couples to gravity must be then of primary importance. Here, unlike the standard model sector which is typically coupled…

高能物理 - 唯象学 · 物理学 2020-10-21 Hemza Azri , Adil Jueid , Canan Karahan , Salah Nasri

Clostridioides difficile infection (C. diff) is the most common cause of death due to secondary infection in hospital patients in the United States. Detection of C. diff cells in scanning electron microscopy (SEM) images is an important…

计算机视觉与模式识别 · 计算机科学 2020-07-15 Ali Memariani , Ioannis A. Kakadiaris

Among features of real immune responses which occur when antigens invade a body,there are two remarkable features. One is that the amount of antibodies produced in the secondary invasion by the same antigens is more than 10 times larger…

种群与进化 · 定量生物学 2007-05-23 Mika Yoshida , Kinji Fuchikami , Tatsuya Uezu

Cell membranes interact via anchored receptor and ligand molecules. Central questions on cell adhesion concern the binding affinity of these membrane-anchored molecules, the mechanisms leading to the receptor-ligand domains observed during…

软凝聚态物质 · 物理学 2009-06-10 Thomas R. Weikl , Mesfin Asfaw , Heinrich Krobath , Bartosz Rozycki , Reinhard Lipowsky

T lymphocytes (T cells) orchestrate adaptive immune responses upon activation. T cell activation requires sufficiently strong binding of T cell receptors (TCRs) on their surface to short peptides (p) derived from foreign proteins, which are…

生物物理 · 物理学 2016-06-22 Andrej Kosmrlj , Arup K. Chakraborty , Mehran Kardar , Eugene I. Shakhnovich

Recent experimental data (H. Nam et al., Phys. Rev. B 100, 094512 (2019)) of critical temperature and gaps measured on superconductor/normal metal heterostructure Pb/Ag, epitaxially grown, shown a interesting not usual behaviour. The…

超导电性 · 物理学 2020-01-29 G. A. Ummarino

We determine the zero-temperature density profile of a cloud of fermionic atoms in a trap subject to a mutual attractive interaction, as the strength of the interaction is progressively increased. We find a significant decrease of the size…

超导电性 · 物理学 2009-11-07 A. Perali , P. Pieri , G. C. Strinati

In weakest link models the failure of a single microscopic element of a brittle material causes the failure of an entire macroscopic specimen, just as a chain fails if one link fails. Pristine samples of glass, such as optical…

材料科学 · 物理学 2015-06-24 J. I. Katz

Filaments are key for star formation models. As part of the study carried out by the Herschel GCC Programme, here we study the filament properties presented in GCC.VII in context with theoretical models of filament formation and evolution.…

A fundamental choice in femtocell deployments is the set of users which are allowed to access each femtocell. Closed access restricts the set to specifically registered users, while open access allows any mobile subscriber to use any…

网络与互联网体系结构 · 计算机科学 2016-11-17 Han-Shin Jo , Ping Xia , Jeffrey G. Andrews

The study of QCD at finite baryon density is severely hampered by the so-called fermion sign problem. As a result, we have no known first principles approach to study nuclear matter, or neutron stars from QCD. On the surface, the large Nc…

高能物理 - 唯象学 · 物理学 2011-10-27 Aleksey Cherman , Brian C. Tiburzi