相关论文: The weakest link bridging germinal center B cells …
Some cells have to take decision based on the quality of surroundings ligands, almost irrespective of their quantity, a problem we name "absolute discrimination". An example of absolute discrimination is recognition of not-self by immune T…
Cells are known to exert forces to sense their physical surroundings for guidance of motion and fate decisions. Here, we propose that cells might do mechanical work to drive their own evolution, taking inspiration from the adaptive immune…
This article is devoted to the analysis of a particle system model for epidemics among a finite population with susceptible, infective and removed individuals (SIR). The infection mechanism depends on the relative distance between…
Plots of equivalent width (or neutral hydrogen column density) versus impact parameter (between the galaxy and quasar line of sight) have been used to support a variety of conclusions about the relationship between galaxies and Ly\alpha…
One of the main reasons for Alzheimer's disease (AD) is the disorder of some neural circuits. Existing methods for AD prediction have achieved great success, however, detecting abnormal neural circuits from the perspective of brain networks…
We have studied the elastic response of actin networks with both compliant and rigid crosslinks by modeling molecular motors as force dipoles. Our finite element simulations show that for compliant crosslinkers such as filamin A, the…
Star formation in the universe's largest galaxies---the ones at the centers of galaxy clusters---depends critically on the thermodynamic state of their hot gaseous atmospheres. Central galaxies with low-entropy, high-density atmospheres…
Let $d_u$ be the degree of a vertex $u$ of a graph $G$. The atom-bond sum-connectivity (ABS) index of a graph $G$ is the sum of the numbers $(1-2(d_v+d_w)^{-1})^{1/2}$ over all edges $vw$ of $G$. This paper gives the characterization of the…
In this work the computer modeling has been used to show that longer ligands allow biological cells (e.g., blood platelets) to withstand stronger flows after their adhesion to solid walls. Mechanistic model of polymer-mediated…
The immune system is a real-time example of an evolving system that navigates the essentially infinite complexity of protein sequence space. How this system responds to disease and vaccination is discussed. Of particular focus is the case…
For any realistic halo profile, the Galactic Center is predicted to be the brightest source of gamma-rays from dark matter annihilations. Due in large part to uncertainties associated with the dark matter distribution and astrophysical…
This paper characterizes the statistics of effective fading gain in multi-tier cellular networks with strongest base station (BS) cell association policy. First, we derive the probability of association with the $n$-th nearest BS in the…
Characterizing user to access point (AP) association strategies in heterogeneous cellular networks (HetNets) is critical for their performance analysis, as it directly influences the load across the network. In this letter, we introduce and…
The letter resolves the long standing debate as to the proper time scale ($<\tau>$) of the onset of the immunological synapse (IS) bond, the non-covalent chemical bond defining the immune pathways involving T-cells and antigen presenting…
Photonic crystals (PCs) with localized optical cavity modes arising from topological domain-wall line defects are simulated for optical biosensing by numerical solution of Maxwell's equations. These consist of a square lattice of square…
A thermal relic, often referred to as a weakly interacting massive particle (WIMP), is a particle produced during the early evolution of the Universe whose present (relic) abundance depends only on its mass and its thermally averaged…
Preferential attachment graphs are random graphs designed to mimic properties of typical real world networks. They are constructed by a random process that iteratively adds vertices and attaches them preferentially to vertices that already…
The major histocompatibility complex (MHC) molecules, which bind peptides for presentation on the cell surface, play an important role in cell-mediated immunity. In light of developing databases and technologies over the years, significant…
Biological tissues exhibit complex behaviors with their dynamics often resembling inert soft matter such as liquids, polymers, colloids, and liquid crystals. These analogies enable physics-based approaches for investigations of emergent…
T-cells are a crucial subset of white blood cells that play a central role in the immune system. When T-cells bind antigens, it leads to cell activation and the induction of an immune response. If T-cells are activated by antigens in vivo…