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In many social, behavioral, and biomedical sciences, treatment effect estimation is a crucial step in understanding the impact of an intervention, policy, or treatment. In recent years, an increasing emphasis has been placed on…

统计方法学 · 统计学 2024-10-10 Xinhai Zhang , Xingye Qiao

Recurrent events, including cardiovascular events, are commonly observed in biomedical studies. Researchers must understand the effects of various treatments on recurrent events and investigate the underlying mediation mechanisms by which…

统计方法学 · 统计学 2025-07-08 Yan-Lin Chen , Yan-Hong Chen , Pei-Fang Su , Huang-Tz Ou , An-Shun Tai

Instrumental variable methods are widely used for inferring the causal effect in the presence of unmeasured confounders. Existing instrumental variable methods for nonlinear outcome models require stringent identifiability conditions. This…

统计方法学 · 统计学 2022-07-01 Sai Li , Zijian Guo

Provider profiling has the goal of identifying healthcare providers with exceptional patient outcomes. When evaluating providers, adjustment is necessary to control for differences in case-mix between different providers. Direct and…

统计方法学 · 统计学 2024-10-28 Herbert Susmann , Yiting Li , Mara A. McAdams-DeMarco , Iván Díaz , Wenbo Wu

Path-specific effects in mediation analysis provide a useful tool for fairness analysis, which is mostly based on nested counterfactuals. However, the dictum ``no causation without manipulation'' implies that path-specific effects might be…

人工智能 · 计算机科学 2021-06-08 Heyang Gong , Ke Zhu

We propose a new Bayesian non-parametric (BNP) method for estimating the causal effects of mediation in the presence of a post-treatment confounder. We specify an enriched Dirichlet process mixture (EDPM) to model the joint distribution of…

统计方法学 · 统计学 2023-05-10 Woojung Bae , Michael J. Daniels , Michael G. Perri

Cluster randomized trials (CRTs) with multiple unstructured mediators present significant methodological challenges for causal inference due to within-cluster correlation, interference among units, and the complexity introduced by multiple…

统计方法学 · 统计学 2025-04-21 Yuki Ohnishi , Fan Li

The identification of latent mediator variables is typically conducted using standard structural equation models (SEMs). When SEM is applied to mediation analysis with a causal interpretation, valid inference relies on the strong assumption…

统计方法学 · 统计学 2025-10-02 Sofia Morelli , Roberto Faleh , Holger Brandt

In causal mediation analysis, the natural direct and indirect effects (natural effects) are nonparametrically unidentifiable in the presence of treatment-induced confounding, which motivated the development of randomized interventional…

统计方法学 · 统计学 2025-07-22 Ang Yu , Li Ge , Felix Elwert

Various methods have recently been proposed to estimate causal effects with confidence intervals that are uniformly valid over a set of data generating processes when high-dimensional nuisance models are estimated by post-model-selection or…

统计方法学 · 统计学 2025-10-07 Niloofar Moosavi , Tetiana Gorbach , Xavier de Luna

Judea Pearl's insight that, when errors are assumed independent, the Pure (aka Natural) Direct Effect (PDE) is non-parametrically identified via the Mediation Formula was `path-breaking' in more than one sense! In the same paper Pearl…

统计方法学 · 统计学 2021-08-31 James M. Robins , Thomas S. Richardson , Ilya Shpitser

Data integration methods aim to extract low-dimensional embeddings from high-dimensional outcomes to remove unwanted variations, such as batch effects and unmeasured covariates, across heterogeneous datasets. However, multiple hypothesis…

统计方法学 · 统计学 2025-12-15 Jin-Hong Du , Kathryn Roeder , Larry Wasserman

We introduce a new method for estimating the mean of an outcome variable within groups when researchers only observe the average of the outcome and group indicators across a set of aggregation units, such as geographical areas. Existing…

统计方法学 · 统计学 2026-05-01 Cory McCartan , Shiro Kuriwaki

Causal effect estimation under networked interference is an important but challenging problem. Available parametric methods are limited in their model space, while previous semiparametric methods, e.g., leveraging neural networks to fit…

机器学习 · 计算机科学 2025-02-27 Weilin Chen , Ruichu Cai , Zeqin Yang , Jie Qiao , Yuguang Yan , Zijian Li , Zhifeng Hao

Mediation analysis is widely used in health science research to evaluate the extent to which an intermediate variable explains an observed exposure-outcome relationship. However, the validity of analysis can be compromised when the exposure…

统计方法学 · 统计学 2025-03-06 Chao Cheng , Donna Spiegelman , Fan Li

Despite having achieved great success for sentiment analysis, existing neural models struggle with implicit sentiment analysis. This may be due to the fact that they may latch onto spurious correlations ("shortcuts", e.g., focusing only on…

计算与语言 · 计算机科学 2022-08-22 Siyin Wang , Jie Zhou , Changzhi Sun , Junjie Ye , Tao Gui , Qi Zhang , Xuanjing Huang

Understanding how much each variable contributes to an outcome is a central question across disciplines. A causal view of explainability is favorable for its ability in uncovering underlying mechanisms and generalizing to new contexts.…

统计方法学 · 统计学 2026-03-09 Weihan Zhang , Zijun Gao

Unmeasured confounding presents a common challenge in observational studies, potentially making standard causal parameters unidentifiable without additional assumptions. Given the increasing availability of diverse data sources, exploiting…

统计方法学 · 统计学 2023-09-18 Shanshan Luo , Yechi Zhang , Wei Li

In causal mediation analysis, identification of existing causal direct or indirect effects requires untestable assumptions in which potential outcomes and potential mediators are independent. This paper defines a new causal direct and…

统计方法学 · 统计学 2020-09-29 Takahiro Hoshino

Analysis of observational studies increasingly confronts the challenge of determining which of a possibly high-dimensional set of available covariates are required to satisfy the assumption of ignorable treatment assignment for estimation…

统计方法学 · 统计学 2022-03-23 Chanmin Kim , Mauricio Tec , Corwin M Zigler