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Complex fluids in shear flow and biased dynamics in crowded environments exhibit counterintuitive features which are difficult to address both at theoretical level and by molecular dynamic simulations. To understand some of these features…

软凝聚态物质 · 物理学 2012-09-19 Francesco Turci , Estelle Pitard , Mauro Sellitto

Polynomial dynamical systems are widely used to model and study real phenomena. In biochemistry, they are the preferred choice for modelling the concentration of chemical species in reaction networks with mass-action kinetics. These systems…

代数几何 · 数学 2014-12-30 Elisenda Feliu

Metabolic networks have two properties that are generally regarded as unrelated: One, they have metabolic reactions whose single knockout is lethal for the organism, and two, they have correlated sets of reactions forming functional…

分子网络 · 定量生物学 2010-12-07 Areejit Samal , Sanjay Jain

Surfaces serve as highly efficient catalysts for a vast variety of chemical reactions. Typically, such surface reactions involve billions of molecules which diffuse and react over macroscopic areas. Therefore, stochastic fluctuations are…

统计力学 · 物理学 2007-10-12 B. Barzel , O. Biham

We present the mechanism of interaction of Wnt network module, which is responsible for periodic sometogenesis, with p53 regulatory network, which is one of the main regulators of various cellular functions, and switching of various…

亚细胞过程 · 定量生物学 2015-03-17 Md. Zubbair Malik , Shahnawaz Ali , Md. Jahoor Alam , Romana Ishrat , R. K. Brojen Singh

We consider reaction-diffusion equations that are stochastically forced by a small multiplicative noise term. We show that spectrally stable traveling wave solutions to the deterministic system retain their orbital stability if the…

偏微分方程分析 · 数学 2020-03-09 Christian Hamster , Hermen Jan Hupkes

Flux analysis is a class of constraint-based approaches to the study of biochemical reaction networks: they are based on determining the reaction flux configurations compatible with given stoichiometric and thermodynamic constraints. One of…

分子网络 · 定量生物学 2015-05-18 A. De Martino , E. Marinari

When attention is directed into the receptive field of a V4 neuron, its contrast response curve is shifted to lower contrast values (Reynolds et al, 2000, Neuron 26:703). Attention also increases the coherence between neurons responding to…

神经元与认知 · 定量生物学 2007-05-23 Calin Buia , Paul Tiesinga

The galactose network is a complex system responsible for galactose metabolism. It has been extensively studied experimentally and mathematically at the unicellular level to broaden our understanding of its regulatory mechanisms at higher…

分子网络 · 定量生物学 2016-02-12 Tina M. Mitre , Anmar Khadra , Michael C. Mackey

Biological networks have evolved to be highly functional within uncertain environments while remaining extremely adaptable. One of the main contributors to the robustness and evolvability of biological networks is believed to be their…

分子网络 · 定量生物学 2008-02-14 Arend Hintze , Christoph Adami

A dynamical system obtains a wide variety of kinetic realizations, which is advantageous for the analysis of biochemical systems. A reaction network, derived from a dynamical system, may or may not possess some properties needed for a…

分子网络 · 定量生物学 2024-05-01 Dylan Antonio Talabis , Eduardo Mendoza

A system responding to a stochastic driving signal can be interpreted as computing, by means of its dynamics, an implicit model of the environmental variables. The system's state retains information about past environmental fluctuations,…

统计力学 · 物理学 2012-10-09 Susanne Still , David A. Sivak , Anthony J. Bell , Gavin E. Crooks

We consider stochastic descriptions of chemical reaction networks in which there are both fast and slow reactions, and for which the time scales are widely separated. We develop a computational algorithm that produces the generator of the…

动力系统 · 数学 2015-12-11 Xingye Kan , Chang Hyeong Lee , Hans G. Othmer

Complex coherent dynamics is present in a wide variety of neural systems. A typical example is the voltage transitions between up and down states observed in cortical areas in the brain. In this work, we study this phenomenon via a…

神经元与认知 · 定量生物学 2015-05-19 Jorge F. Mejias , Hilbert J. Kappen , Joaquin J. Torres

Reaction diffusion systems are often used to study pattern formation in biological systems. However, most methods for understanding their behavior are challenging and can rarely be applied to complex systems common in biological…

偏微分方程分析 · 数学 2013-05-24 William R. Holmes

We consider a general class of translation-invariant systems with a specific category of output nonlinearities motivated by biological sensing. We show that no dynamic output feedback can stabilize this class of systems to an isolated…

系统与控制 · 电气工程与系统科学 2025-02-21 Debojyoti Biswas , Eduardo D. Sontag , Noah J. Cowan

The evolution of a system induced by counter-diabatic driving mimics the adiabatic dynamics without the requirement of slow driving. Engineering it involves diagonalizing the instantaneous Hamiltonian of the system and results in the need…

量子物理 · 物理学 2013-09-05 Adolfo del Campo

Understanding the emergent behavior of chemical reaction networks (CRNs) is a fundamental aspect of biology and its origin from inanimate matter. A closed CRN monotonically tends to thermal equilibrium, but when it is opened to external…

分子网络 · 定量生物学 2024-05-16 Masanari Shimada , Pegah Behrad , Eric De Giuli

We study the dynamical response of a harmonically trapped two-component few-fermion mixture to the external gaussian potential barrier moving across the system. The simultaneous role played by inter-particle interactions, rapidity of the…

量子气体 · 物理学 2021-05-26 Dillip K. Nandy , Tomasz Sowiński

New advances in nano sciences open the door for scientists to study biological processes on a microscopic molecule-by-molecule basis. Recent single-molecule biophysical experiments on enzyme systems, in particular, reveal that enzyme…

应用统计 · 统计学 2012-09-28 Chao Du , S. C. Kou
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