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Cardiovascular modeling has rapidly advanced over the past few decades due to the rising needs for health tracking and early detection of cardiovascular diseases. While 1-D arterial models offer an attractive compromise between…

A patient-specific fluid-structure interaction (FSI) model of a phase-contrast magnetic resonance angiography (PC-MRA) imaged arteriovenous fistula is presented. The numerical model is developed and simulated using a commercial multiphysics…

医学物理 · 物理学 2018-01-30 W. P. Guess , B. D. Reddy , A. McBride , B. Spottiswoode , J. Downs , T. Franz

Arterial biomechanical indicators have long been recognized as fundamental contributors to the physiology and pathology of cardiovascular systems. Probing the multiple biomechanical parameters of arteries simultaneously at different time…

We study the impact of using fluid-structure interactions (FSI) to simulate blood flow in a large stenosed artery. We compare typical flow configurations using Navier-Stokes in a rigid geometry setting to a fully coupled FSI model. The…

计算物理 · 物理学 2021-02-01 Lukas Failer , Piotr Minakowski , Thomas Richter

In this work, we present mixed dimensional models for simulating blood flow and transport processes in breast tissue and the vascular tree supplying it. These processes are considered, to start from the aortic inlet to the capillaries and…

组织与器官 · 定量生物学 2022-10-10 Marvin Fritz , Tobias Köppl , J. Tinsley Oden , Andreas Wagner , Barbara Wohlmuth , Chengyue Wu

A finite element analysis of flows of an Oldroyd-B fluid is developed, to simulate blood flow in an arteriovenous fistula. The model uses a combination of a standard conforming finite element approximation for the momentum equation, and the…

医学物理 · 物理学 2020-03-19 Nkosilathi Vundla , B. Daya Reddy

We propose and analyse the properties of a new class of models for the electromechanics of cardiac tissue. The set of governing equations consists of nonlinear elasticity using a viscoelastic and orthotropic exponential constitutive law…

In this paper, we are concerned with the simulation of blood flow in microvascular networks and the surrounding tissue. To reduce the computational complexity of this issue, the network structures are modeled by a one-dimensional graph,…

数值分析 · 数学 2023-05-01 Ettore Vidotto , Timo Koch , Tobias Köppl , Rainer Helmig , Barbara Wohlmuth

Computational fluid dynamics (CFD) based simulation of coronary blood flow provides valuable hemodynamic markers, such as pressure gradients, for diagnosing coronary artery disease (CAD). However, CFD is computationally expensive,…

计算机视觉与模式识别 · 计算机科学 2025-12-12 Rene Lisasi , Michele Esposito , Chen Zhao

Using analytical expressions for the pressure and velocity waveforms in tapered vessels, we construct a linear 1D model for wave propagation in stenotic vessels in the frequency domain. We demonstrate that using only two parameters to…

流体动力学 · 物理学 2019-07-24 George Papadakis , Jean Raspaud

The arterial system dynamically loads the heart through changes in arterial compliance. The pressure-volume relation of arteries is known to be nonlinear, but arterial compliance is often modeled as a constant value, due to ease of…

定量方法 · 定量生物学 2014-03-26 Timothy S. Phan , John K-J. Li

To accurately simulate all phases of the cardiac cycle, computational models of hemodynamics in heart chambers need to include a sufficiently faithful model of cardiac valves. This can be achieved efficiently through resistive methods, and…

数值分析 · 数学 2025-06-05 Michele Bucelli , Luca Dede'

State of the art research and treatment of biological tissues require accurate and efficient methods for describing their mechanical properties. Indeed, micromechanics motivated approaches provide a systematic method for elevating relevant…

软凝聚态物质 · 物理学 2012-05-04 Gal deBotton , Tal Oren

The analysis of quantitative hemodynamics and luminal pressure may add valuable information to aid treatment strategies and prognosis for aortic dissections. This work directly compared in vitro 4D-flow magnetic resonance imaging (MRI),…

Usually, clinicians assess the correct hemodynamic behavior and fetal well-being during the gestational age thanks to their professional expertise, with the support of some indices defined for Doppler fetal waveforms. Although this approach…

Internal haemorrhage, often leading to cardio-vascular arrest happens to be one of the prime sources of high fatality rates in mammals. We propose a simplistic model of fluid flow to specify the location of the haemorrhagic spots, which, if…

软凝聚态物质 · 物理学 2013-04-01 Amit K. Chattopadhyay , Shreekantha Sil

We present a new computational model for the numerical simulation of blood flow in the human left heart. To this aim, we use the Navier-Stokes equations in an Arbitrary Lagrangian Eulerian formulation to account for the endocardium motion…

In this paper, we introduce an adapted one-dimensional (1D) reduced model aimed at analyzing blood flow within stenosed arteries. Differing from the prevailing 1D model \cite{Formaggia2003, Sherwin2003_2, Sherwin2003, Quarteroni2004,…

数值分析 · 数学 2024-09-25 Suncica Canic , Shihan Guo , Yifan Wang , Xiaohe Yue , Haibiao Zheng

Direct numerical simulations of turbulent flow in a channel with one rigid and one viscoelastic wall are performed. An Eulerian-Eulerian model is adopted with a level-set approach to identify the fluid-compliant material interface. Focus is…

流体动力学 · 物理学 2021-11-03 Amir Esteghamatian , Joseph Katz , Tamer A. Zaki

Fast and realistic coupling of blood flow and vessel wall is of great importance to virtual surgery. In this paper, we propose a novel data-driven coupling method that formulates physics-based blood flow simulation as a regression problem,…

图形学 · 计算机科学 2019-01-25 Xuejie Mai , Zhiyong Yuan , Qianqian Tong , Tianchen Yuan , Jianhui Zhao