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相关论文: Computational hemodynamics in arteries with the on…

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Image-based modeling is essential for understanding cardiovascular hemodynamics and advancing the diagnosis and treatment of cardiovascular diseases. Constructing patient-specific vascular models remains labor-intensive, error-prone, and…

计算机视觉与模式识别 · 计算机科学 2025-03-18 Pan Du , Delin An , Chaoli Wang , Jian-Xun Wang

Computational fluid dynamics (CFD) can be used to simulate vascular haemodynamics and analyse potential treatment options. CFD has shown to be beneficial in improving patient outcomes. However, the implementation of CFD for routine clinical…

Active arterial mechanics, governed by vascular smooth muscle contraction, are critical to physiological regulation, cardiovascular disease progression, and clinical diagnosis. Although various in vivo methods have been developed to assess…

医学物理 · 物理学 2026-01-21 Yuxuan Jiang , Yanping Cao

Computational fluid dynamics (CFD) studies of left atrial flows have reached a sophisticated level, e.g., revealing plausible relationships between hemodynamics and stresses with atrial fibrillation. However, little focus has been on…

Altered hemodynamics play a key role in cerebrovascular diseases such as aneurysms and stenosis. However, in vivo imaging lacks the spatial resolution required to resolve flow dynamics in small vessels. This study presents an experimental…

流体动力学 · 物理学 2026-05-25 Job van Essen , Ahmed Sharaf , Denzel Hopman , Selene Pirola , Paola Fanzio

- Modeling Human cardiovascular system is always an important issue. One of the most effective methods is using lumped model to reach to a complete model of human cardiovascular system. Such modeling with advanced considerations is used in…

Objective: to develop quantitative methods for the clinical interpretation of the ballistocardiogram (BCG). Methods: a closed-loop mathematical model of the cardiovascular system is proposed to theoretically simulate the mechanisms…

Valvular heart diseases are growing concern in impoverished parts of the world, such as Southern-Africa, claiming more than 31 % of total deaths related to cardiovascular diseases. The ability to model the effects of regurgitant and…

医学物理 · 物理学 2022-04-11 Ryno Laubscher , Jacques Liebenberg , Philip Herbst

Numerical simulations have been extensively used in the past two decades for the study of intracranial aneurysms (IAs), a dangerous disease that occurs in the arteries that reach the brain. They may affect up to 10 % of the world's…

流体动力学 · 物理学 2022-10-12 Iago Oliveira , Philip Cardiff , Carlos E. Baccin , José Gasche

We study the behavior of the pulse waves of water into a flexible tube for application to blood flow simulations. In pulse waves both fluid friction and wall viscosity are damping factors, and difficult to evaluate separately. In this…

Modeling cardiovascular anatomies poses a significant challenge due to their complex, irregular structures and inherent pathological conditions. Numerical simulations, while accurate, are often computationally expensive, limiting their…

机器学习 · 计算机科学 2025-03-25 Navaneeth N , Souvik Chakraborty

Pulmonary hypertension is a cardiovascular disorder manifested by elevated arterial blood pressure together with vessel wall stiffening and thickening due to alterations in collagen, elastin and smooth muscle cells. Hypoxia-induced (type 3)…

组织与器官 · 定量生物学 2022-02-28 Mansoor A. Haider , Katherine J. Pearce , Naomi C. Chesler , Nicholas A. Hill , Mette S. Olufsen

Viscoelastic rate-type fluid models constitute a fundamental framework for the mathematical description of complex materials exhibiting coupled elastic and viscous effects, with a wide range of applications in engineering, biomaterials, and…

偏微分方程分析 · 数学 2026-05-01 Miroslav Bulíček , Tomáš Los , Jakub Woźnicki

Despite tremendous advances in cardiovascular medicine, significant opportunities remain to improve coronary artery disease (CAD) prevention and treatment strategies. The key limitation lies in the understanding of disease formation and…

Application of computation in many fields are growing fast in last two decades. Increasing on computation performance helps researchers to understand natural phenomena in many fields of science and technology including in life sciences.…

生物物理 · 物理学 2014-02-27 Suprijadi , Mohamad Rendi , Petrus Subekti , Sparisoma Viridi

Investigating blood flow in the cardiovascular system is crucial for assessing cardiovascular health. Computational approaches offer some non-invasive alternatives to measure blood flow dynamics. Numerical simulations based on traditional…

数值分析 · 数学 2024-06-07 Han Zhang , Raymond Chan , Xue-Cheng Tai

A major challenge in the computational fluid dynamics modeling of the heart function is the simulation of isovolumetric phases when the hemodynamics problem is driven by a prescribed boundary displacement. During such phases, both…

数值分析 · 数学 2022-08-25 Alberto Zingaro , Michele Bucelli , Ivan Fumagalli , Luca Dede' , Alfio Quarteroni

Mathematical modeling at the level of the full cardiovascular system requires the numerical approximation of solutions to a one-dimensional nonlinear hyperbolic system describing flow in a single vessel. This model is often simulated by…

计算物理 · 物理学 2015-04-22 Sebastian Acosta , Charles Puelz , Beatrice Riviere , Daniel J. Penny , Craig G. Rusin

We consider a multiscale approach based on immersed methods for the efficient computational modeling of tissues composed of an elastic matrix (in two or three-dimensions) and a thin vascular structure (treated as a co-dimension two…

数值分析 · 数学 2021-11-18 Luca Heltai , Alfonso Caiazzo

We investigate through numerical simulations the hydrodynamic interactions between two rigid spherical particles suspended on the axis of a cylindrical tube filled with an elastoviscoplastic fluid subjected to pressure-driven flow. The…

流体动力学 · 物理学 2025-05-14 Giancarlo Esposito , John Tsamopoulos , Massimiliano Maria Villone , Gaetano D'Avino