相关论文: A mathematical view on head lice infestations

It is estimated that around 80\% of the world's population live in areas susceptible to at-least one major vector borne disease, and approximately 20% of global communicable diseases are spread by mosquitoes. Furthermore, the outbreaks of…

Drug-induced liver injury (DILI) remains a leading cause of late-stage clinical trial attrition. However, existing computational predictors primarily rely on binary classification, a framing that limits generalization and yields no…

The spread of tick-borne pathogens represents an important threat to human and animal health in many parts of Eurasia. Here, we analysed a 9-year time series of Ixodes ricinus ticks feeding on Apodemus flavicollis mice (main…

In this paper, we introduce a control strategy for applying the Sterile Insect Technique (SIT) to eliminate the population of Aedes mosquitoes which are the vectors of various deadly diseases like dengue, zika, chikungunya... in a wide…

Sea lice are a threat to the health of both wild and farmed salmon and an economic burden for salmon farms. With a free living larval stage, sea lice can disperse tens of kilometers in the ocean between salmon farms, leading to connected…

When an infectious disease propagates throughout society, the incidence function may rise at first due to an increase in pathogenicity and then decrease due to inhibitory effects until it reaches saturation. Effective vaccination and…

We explore the emergence of persistent infection in a patch of population, where the disease progression of the individuals is given by the SIRS model and an individual becomes infected on contact with another infected individual. We…

Dengue is a vector-borne disease transmitted from an infected human to an Aedes mosquito, during a blood-meal. Dengue is still a major public health problem. A model for the disease transmission is presented, composed by human and…

The COVID-19 pandemic has resulted in more than 14.5 million infections and 6,04,917 deaths in 212 countries over the last few months. Different drug intervention acting at multiple stages of pathogenesis of COVID-19 can substantially…

Mathematical models of living cells have been successively refined with advancements in experimental techniques. A main concern is striking a balance between modelling power and the tractability of the associated mathematical analysis. In…

We are interested in modeling some two-level population dynamics, resulting from the interplay of ecological interactions and phenotypic variation of individuals (or hosts) and the evolution of cells (or parasites) of two types living in…

The study of infectious disease propagation is essential for understanding and controlling epidemics. One of the most useful tools for gaining insights into the spread of infectious diseases is mathematical modelling. In terms of…

A system of partial differential equations is derived as a model for the dynamics of a honey bee colony with a continuous age distribution, and the system is then extended to include the effects of a simplified infectious disease. In the…

We introduce a model of parasite infection in a cell population, where cells can be infected, either at birth through maternal transmission, from a contact with the parasites reservoir, or because of the parasites released in the cell…

In this study initially, we propose an age structured model and calculate the equilibrium points and basic reproduction number. Later we propose an optimal control problem to understand the roles of treatment in controlling the epidemic.…

This paper investigates the effect of drug treatment on the standard within-host HIV model, assuming that therapy occurs periodically. It is shown that eradication is possible under these periodic regimes, and we quantitatively characterize…

Controlling pest insects is a challenge of main importance to preserve crop production. In the context of Integrated Pest Management (IPM) programs, we develop a generic model to study the impact of mating disruption control using an…

Human mobility is a key factor in spatial disease dynamics and related phenomena. In computational models host mobility is typically modelled by diffusion in space or on metapolulation networks. Alternatively, an effective force of…

Aedes Aegypti is the vector of several deadly diseases, including Zika. Effective and sustainable vector control measures must be deployed to keep A. aegypti numbers under control. The distribution of A. Aegypti is subject to spatial and…

In addressing the origins of Darwinian evolution, recent experimental work has been focussed on the discovery of simple physical effects which would provide a relevant selective advantage to protocells competing with each other for a…