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We cast the metabolism of interacting cells within a statistical mechanics framework considering both, the actual phenotypic capacities of each cell and its interaction with its neighbors. Reaction fluxes will be the components of…

分子网络 · 定量生物学 2020-04-08 Jorge Fernandez-de-Cossio-Diaz , Roberto Mulet

This review provides a dynamical systems perspective on psychiatric symptoms and disease, and discusses its potential implications for diagnosis, prognosis, and treatment. After a brief introduction into the theory of dynamical systems, we…

神经元与认知 · 定量生物学 2018-09-18 Daniel Durstewitz , Quentin J. M. Huys , Georgia Koppe

What can we hope to learn about brains from the free energy principle? In adopting the "primordial soup" physical model, Bruineberg et al. perpetuate the unsupported notion that the free energy principle has a meaningful physical--and…

神经元与认知 · 定量生物学 2022-01-14 Donald Spector , Daniel Graham

Perceptual rivalry, where conflicting sensory information leads to alternating perceptions crucial for associated cognitive function, has attracted researcher's attention for long. Despite progresses being made, recent studies have revealed…

神经元与认知 · 定量生物学 2026-03-25 Yuxuan Wu , Liufang Xu , Jin Wang

Traditional approaches to understanding the brain's resilience to neuropathology have identified neurophysiological variables, often described as brain or cognitive 'reserve,' associated with better outcomes. However, mechanisms of function…

神经元与认知 · 定量生物学 2017-01-18 John D. Medaglia , Fabio Pasqualetti , Roy H. Hamilton , Sharon L. Thompson-Schill , Danielle S. Bassett

The limited spectrum resources and dramatic growth of high data rate communications have motivated opportunistic spectrum access using the promising concept of cognitive radio networks. Although this concept has emerged primarily to enhance…

网络与互联网体系结构 · 计算机科学 2013-12-03 Hossein Shokri-Ghadikolaei , Ioannis Glaropoulos , Viktoria Fodor , Carlo Fischione , Konstantinos Dimou

Generative models of brain activity have been instrumental in testing hypothesized mechanisms underlying brain dynamics against experimental datasets. Beyond capturing the key mechanisms underlying spontaneous brain dynamics, these models…

神经元与认知 · 定量生物学 2024-11-18 Rishikesan Maran , Eli J. Müller , Ben D. Fulcher

This paper provides a perspective on applying the concepts of information thermodynamics, developed recently in non-equilibrium statistical physics, to problems in theoretical neuroscience. Historically, information and energy in…

神经元与认知 · 定量生物学 2024-09-27 Jan Karbowski

Mild Traumatic Brain Injury (mTBI) is a common brain injury and affects a diverse group of people: soldiers, constructors, athletes, drivers, children, elders, and nearly everyone. Thus, having a well-established, fast, cheap, and accurate…

信号处理 · 电气工程与系统科学 2022-08-19 Weiqing Gu , Ryan Chang , Bohan Yang

Modeling of consciousness-related phenomena and neuroengineering are fields that are rapidly growing together. We review recent approaches and developments and point out some promising directions of future research: Understanding the…

神经元与认知 · 定量生物学 2013-12-31 Jens Christian Claussen , Ulrich G. Hofmann

We provide a brief review of the common assumptions about biological learning with findings from experimental neuroscience and contrast them with the efficiency of gradient-based learning in recurrent neural networks. The key issues…

Biomechanics is a scientific discipline that studies the forces acting on a body and the effects they produce. In this paper, we bring together biomechanists and networking researchers to shed light into how research efforts in…

网络与互联网体系结构 · 计算机科学 2021-03-30 Spyridon Mastorakis , Andreas Skiadopoulos , Susmit Shannigrahi , Aaron Likens , Boubakr Nour , Nicholas Stergiou

The field of computational modeling of the brain is advancing so rapidly that now it is possible to model large scale networks representing different brain regions with a high level of biological detail in terms of numbers and synapses. For…

Traumatic brain injury (TBI) disrupts thalamocortical connectivity, contributing to cognitive impairment and post-traumatic epilepsy (PTE). This study presents a novel tractography-based framework that leverages diffusion maps to capture…

定量方法 · 定量生物学 2025-10-21 Akul Sharma , Anand A. Joshi , Richard M. Leahy

The 'free energy principle' (FEP) has been suggested to provide a unified theory of the brain, integrating data and theory relating to action, perception, and learning. The theory and implementation of the FEP combines insights from…

神经元与认知 · 定量生物学 2017-05-26 Christopher L. Buckley , Chang Sub Kim , Simon McGregor , Anil K. Seth

We present the epithelial-to-mesenchymal transition (EMT) from two perspectives: experimental/technological and theoretical. We review the state of the current understanding of the regulatory networks that underlie EMT in three…

A perfectly rational decision-maker chooses the best action with the highest utility gain from a set of possible actions. The optimality principles that describe such decision processes do not take into account the computational costs of…

人工智能 · 计算机科学 2013-12-25 Jordi Grau-Moya , Daniel A. Braun

This paper presents the principal challenges and opportunities associated with computational biomechanics research. The underlying cognitive control involved in the process of human motion is inherently complex, dynamic, multidimensional,…

Energy is an abstract science concept, so the ways that we think and talk about energy rely heavily on ontological metaphors: metaphors for what kind of thing energy is. Two commonly used ontological metaphors for energy are energy as a…

物理教育 · 物理学 2014-12-08 Benjamin W. Dreyfus , Ayush Gupta , Edward F. Redish

The brain is a highly efficient system evolved to achieve high performance with limited resources. We propose that dendrites make information processing and storage in the brain more efficient through the segregation of inputs and their…

神经元与认知 · 定量生物学 2023-06-13 Roman Makarov , Michalis Pagkalos , Panayiota Poirazi