相关论文: A review of available software for adaptive clinic…
Background: Advanced adaptive randomised clinical trials are increasingly used. Compared to their conventional counterparts, their flexibility may make them more efficient, increase the probability of obtaining conclusive results without…
Adaptive designs for clinical trials permit alterations to a study in response to accumulating data in order to make trials more flexible, ethical and efficient. These benefits are achieved while preserving the integrity and validity of the…
The COVID-19 pandemic has led to an unprecedented response in terms of clinical research activity. An important part of this research has been focused on randomized controlled clinical trials to evaluate potential therapies for COVID-19.…
Analytical code is essential for reproducing diagnostic and prognostic prediction model research, yet code availability in the published literature remains limited. While the TRIPOD statements set standards for reporting prediction model…
Despite the massive costs and widespread harms of substance use, most individuals with substance use disorders (SUDs) receive no treatment at all. Digital therapeutics platforms are an emerging low-cost and low-barrier means of extending…
Although agile software development methods have caught the attention of software engineers and researchers worldwide, scientific research still remains quite scarce. The aim of this study is to order and make sense of the different agile…
Context: Agile development methodologies in the software industry have increased significantly over the past decade. Although one of the main aspects of agile software development (ASD) is less documentation, there have always been…
Self-adaptive software can assess and modify its behavior when the assessment indicates that the program is not performing as intended or when improved functionality or performance is available. Since the mid-1960s, the subject of system…
In the context of clinical research, computational models have received increasing attention over the past decades. In this systematic review, we aimed to provide an overview of the role of so-called in silico clinical trials (ISCTs) in…
Software systems are increasingly making decisions on behalf of humans, raising concerns about the fairness of such decisions. Such concerns are usually attributed to flaws in algorithmic design or biased data, but we argue that they are…
With increasing interest in adaptive clinical trial designs, challenges are present to drug supply chain management which may offset the benefit of adaptive designs. Thus, it is necessary to develop an optimization tool to facilitate the…
A large number of computational scientific research projects make use of open source software packages. However, the development process of such tools frequently differs from conventional software development; partly because of the nature…
Context: Over the last decade, software researchers and engineers have developed a vast body of methodologies and technologies in requirements engineering for self-adaptive systems. Although existing studies have explored various aspects of…
The increasing demand for programmers has led to a surge in participants in programming courses, making it increasingly challenging for instructors to assess student code manually. As a result, automated programming assessment systems…
The trend toward open science increases the pressure on authors to provide access to the source code and data they used to compute the results reported in their scientific papers. Since sharing materials reproducibly is challenging, several…
Agentic AI in software product development is increasingly adopted by organizations, yet the field lacks a consolidated synthesis of where adoption is mature, which architectural patterns dominate, and what limitations and coping mechanisms…
Autonomous driving has shown great potential to reform modern transportation. Yet its reliability and safety have drawn a lot of attention and concerns. Compared with traditional software systems, autonomous driving systems (ADSs) often use…
Being able to access software in daily life is vital for everyone, and thus accessibility is a fundamental challenge for software development. However, given the number of accessibility issues reported by many users, e.g., in app reviews,…
Scientific software is one of the key elements for reproducible research. However, classic publications and related scientific software are typically not (sufficiently) linked, and it lacks tools to jointly explore these artefacts. In this…
In recent years, the interest in developing adaptive solutions for online testing has grown significantly in the industry. While the advances related to this relative new technology have been developed in multiple domains, it lacks in the…