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We study the transport of bacteria in a porous media modeled by a square channel containing one cylindrical obstacle via molecular dynamics simulations coupled to a lattice Boltzmann fluid. Our bacteria model is a rod-shaped rigid body…

软凝聚态物质 · 物理学 2020-11-30 Miru Lee , Christoph Lohrmann , Kai Szuttor , Harold Auradou , Christian Holm

We have developed a mathematical model of regulation of expression of the Escherichia coli lac operon, and have investigated bistability in its steady-state induction behavior in the absence of external glucose. Numerical analysis of…

细胞行为 · 定量生物学 2008-02-12 David W. Dreisigmeyer , Jelena Stajic , Ilya Nemenman , William S. Hlavacek , Michael E. Wall

A mathematical model of Min oscillation in Escherichia coli is numerically studied. The oscillatory state and hysteretic transition are explained with simpler coupled differential equations. Next, we propose a simple model of cell growth…

适应与自组织系统 · 物理学 2019-10-23 Hidetsugu Sakaguchi , Yuka Kawasaki

Growth rate is one of the most important and most complex phenotypic characteristics of unicellular microorganisms, which determines the genetic mutations that dominate at the population level, and ultimately whether the population will…

细胞行为 · 定量生物学 2019-01-23 Thomas P. Wytock , Adilson E. Motter

In natural environments, solid surfaces present both opportunities and challenges for bacteria. On one hand, they serve as platforms for biofilm formation, crucial for bacterial colonization and resilience in harsh conditions. On the other…

生物物理 · 物理学 2025-07-01 Antai Tao , Guangzhe Liu , Rongjing Zhang , Junhua Yuan

We confine a dense suspension of motile \textit{Escherichia coli} inside a spherical droplet in a water-in-oil emulsion, creating a "bacterially" propelled droplet. We show that droplets move in a persistent random walk, with a persistence…

软凝聚态物质 · 物理学 2019-12-10 Gabriel Ramos , Maria Luisa Cordero , Rodrigo Soto

We develop a numerical framework to simulate the locomotion of a flagellated bacterium with a spheroidal head (such as Escherichia coli) in biological fluids like mucus, which are entangled polymer solutions exhibiting elasto-viscoplastic…

流体动力学 · 物理学 2026-04-01 Arjun Sharma , Sabarish V. Narayanan , Sarah Hormozi , Donald L. Koch

Growing living cultures of Escherichia coli bacteria were investigated using real-time in situ rheology and rheo-imaging measurements. In the early stages of growth (lag phase), and when subjected to a constant stationary shear, the…

生物物理 · 物理学 2016-12-21 R. Portela , P. Patrício , P. L. Almeida , R. G. Sobral , J. M. Franco , C. R. Leal

In some conditions, bacteria self-organise into biofilms, supracellular structures made of a self-produced embedding matrix, mainly composed on polysaccharides, DNA, proteins and lipids. It is known that bacteria change their colony/matrix…

We have investigated the growth of Escherichia coli E.coli, a mesophilic bacterium, as a function of pressure $P$ and temperature $T$. E.coli can grow and divide in a wide range of pressure (1-400atm) and temperature ($23-40^{\circ}$C). For…

生物物理 · 物理学 2015-06-11 Pradeep Kumar , Albert Libchaber

Unraveling bacterial strategies for spatial exploration is crucial for understanding the complexity in the organization of life. Bacterial motility determines the spatio-temporal structure of microbial communities, controls infection…

Understanding mixing and transport of passive scalars in active fluids is important to many natural (e.g. algal blooms) and industrial (e.g. biofuel, vaccine production) processes. Here, we study the mixing of a passive scalar (dye) in…

Bacterial communities such as biofilms are widely recognised as being important for survival and persistence of bacteria in harsh environments. Mechanistic models of biofilm growth indicate that the way in which the surface is seeded can…

定量方法 · 定量生物学 2007-05-23 Leah R. Johnson

We study the effect of discreteness on various models for patterning in bacterial colonies. In a bacterial colony with branching pattern, there are discrete entities - bacteria - which are only two orders of magnitude smaller than the…

无序系统与神经网络 · 物理学 2007-05-23 Inon Cohen , Ido Golding , Yonathan Kozlovsky , Eshel Ben-Jacob

Mathematical models have been widely used to describe the collective movement of bacteria by chemotaxis. In particular, bacterial concentration waves traveling in a narrow channel have been experimentally observed and can be precisely…

偏微分方程分析 · 数学 2016-04-15 Casimir Emako , Charlène Gayrard , Axel Buguin , Luís Neves de Almeida , Nicolas Vauchelet

Antibiotic-resistant bacterial infection becomes one of the most serious risks to public health care today. However, discouragingly, the development of new antibiotics has been little progressed over the last decade. There is an urgent need…

生物大分子 · 定量生物学 2015-07-20 Jeong Chan Park , Myung-Hwan Jung

Which properties of metabolic networks can be derived solely from stoichiometric information about the network's constituent reactions? Predictive results have been obtained by Flux Balance Analysis (FBA), by postulating that cells set…

分子网络 · 定量生物学 2018-09-05 Daniele De Martino , Anna MC Andersson , Tobias Bergmiller , Călin C Guet , Gašper Tkačik

The lac operon of Escherichia coli exhibits bistability. Early studies showed that bistability occurs during growth on TMG/succinate and lactose + glucose, but not during growth on lactose. More recent studies with lacGFP-transfected cells…

分子网络 · 定量生物学 2007-07-10 A. Narang S. S. Pilyugin

Shifting from traditional hazard-based food safety management toward risk-based management requires statistical methods for evaluating intermediate targets in food production, such as microbiological criteria (MC), in terms of their effects…

应用统计 · 统计学 2015-11-06 Jukka Ranta , Roland Lindqvist , Ingrid Hansson , Pirkko Tuominen , Maarten Nauta

Densely packed, motile bacteria can adopt collective states not seen in conventional, passive materials. These states remain in many ways mysterious, and their physical characterization can aid our understanding of natural bacterial…